Clinical trials
PARKINSON DISEASE (Disorder) clinical trials
Below are recruiting parkinson disease (disorder) clinical trials, each written for real people, not researchers. We’re tracking 497 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Los Angeles, CaliforniaAges 18 years+ - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT07213219Recruiting
PET-MRI scan for Parkinson's with sleep behavior disorder
This trial uses a combined PET and MRI scan to study the brain's reward system in people with Parkinson's disease who also have REM sleep behavior disorder (RBD). It aims to understand how the brain changes and may help guide future treatments.
Clermont-FerrandAges 45–80 - NCT06733077Recruiting
Digital services for Parkinson's disease
This study is developing digital services for people with Parkinson's disease and also includes healthy volunteers. It aims to understand movement problems like freezing of gait and festination, and uses a virtual reality system to measure these issues.
ExeterAges 18 years+ - NCT06899022Recruiting
Attention and eye movement in Parkinson's disease
This study looks at how attention and eye movements work in people with Parkinson's disease, essential tremor, or dystonia. It tests abilities during deep brain stimulation (DBS) surgery and when DBS settings are changed.
Omaha, NebraskaAges 19–90 - NCT06920134Recruiting
Spinal cord stimulation for blood pressure in Parkinson's disease
This trial tests if electrical stimulation of the spinal cord can help manage blood pressure drops (orthostatic hypotension) in people with Parkinson's and related conditions. It might make daily activities like standing and walking easier.
Lausanne, Canton of VaudAges 18–90 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT05769699Recruiting
Blood test study for Parkinson’s stages
This study measures blood biomarkers (measurable substances in blood) in people with Parkinson’s at different stages. It may help doctors understand how Parkinson’s changes over time and could guide future testing or treatments.
RomaAges 18–80 - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT06500182Recruiting
Horseback riding therapy for older adults with Parkinson's disease
This study tests if horseback riding therapy can help people with Parkinson's disease who are 75 or older. It aims to see if this gentle activity improves balance, walking, and quality of life.
Saint-Quentin, AisneAges 75 years+ - NCT06570421Recruiting
Nerve stimulation for Parkinson's and essential tremor
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
OstravaAges 18 years+ - NCT06588920Recruiting
Brain activity, thinking, and walking study for Parkinson's
This study looks at how brain activity relates to thinking and walking in people with Parkinson's disease. It may help understand the connections between these functions.
TaipeiAges 40–80 - NCT06798844RecruitingPhase 2
Spinal cord stimulation for freezing of gait in Parkinson's
This trial tests whether a spinal cord stimulator can reduce freezing of gait (feeling stuck when walking) in people with Parkinson's disease. It may help you if you have daily freezing episodes and are willing to have a small device implanted.
LeuvenAges 40–80 - NCT07097298Recruiting
Empathy and compassion study for Parkinson's patients and caregivers
This study explores empathy and self-compassion in people with Parkinson's disease and their caregivers. If you have mild to moderate Parkinson's and a caregiver at home, you and your caregiver may join together to help researchers understand how to better support both of you.
LuganoAges 50–80 - NCT07156773RecruitingPhase 2
Nasal spray for Parkinson's off episodes
This study tests a new nasal spray called XJN010 for people with Parkinson's who have 'off' episodes—times when their regular medication wears off and symptoms come back. The goal is to see if the spray can safely and effectively help during those periods.
Guangzhou, GuangdongAges 30–85 - NCT06285643RecruitingPhase 2
Gene therapy for moderate Parkinson's disease
This trial tests a gene therapy (AAV2-GDNF) to see if it can slow or improve symptoms of Parkinson's disease. It is for people who have had moderate Parkinson's for 4 to 10 years and still respond to levodopa therapy.
Phoenix, ArizonaAges 45–75 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100 - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99 - NCT05822388Recruiting
Deep brain stimulation and memory changes in Parkinson’s
This study looks at whether deep brain stimulation (a surgical treatment for Parkinson’s disease) affects thinking and memory over time. It compares Parkinson’s participants to people without Parkinson’s to better understand what changes happen with treatment.
Charleston, South CarolinaAges 18 years+ - NCT06617884Recruiting
Home balance training for movement disorders
This study tests a home-based walking and balance training program for people with cerebellar ataxia or Parkinson's disease. The training is done at home, so you don't need to travel. The goal is to see if this simple exercise program can improve your walking and balance.
Düsseldorf, North Rhine-WestphaliaAges 18–75 - NCT06994728Recruiting
How DBS affects vision and freezing of gait in Parkinson's
This trial looks at how deep brain stimulation (DBS) affects the way you see and move, and how that relates to freezing of gait (when your feet suddenly feel stuck). If you have Parkinson's disease, already have a DBS device, and experience freezing, this study may help researchers understand your symptoms better.
Charleston, South CarolinaAges 18 years+
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Common questions
- Are there clinical trials for parkinson disease (disorder)?
- Yes. Clin2 currently lists 497 recruiting parkinson disease (disorder) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease (disorder) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease (disorder) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.