Clinical trials
Phase 1 clinical trials
Below are recruiting phase 1 clinical trials, each written for real people, not researchers. We’re tracking 285 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07181369RecruitingPhase 1
Study of GTX-B001 for chronic inducible urticaria
This trial tests a new drug, GTX-B001, in healthy people and those with a type of hives called chronic inducible urticaria (specifically cold-induced or scratch-induced hives). The goal is to see if it's safe and helps control symptoms that don't respond well to standard antihistamines.
BerlinAges 18–75 - NCT07182149RecruitingPhase 1
Testing a new drug for advanced solid tumors
This trial tests a new drug called NRM-823 for people with several types of advanced cancer that have stopped responding to standard treatments. The goal is to see if the drug is safe and how well it works.
Denver, ColoradoAges 18 years+ - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT07222020RecruitingPhase 1
Study of a new vaginal film for healthy women
This trial tests a new vaginal film (KB15A) in healthy women aged 18–45. The film is placed in the vagina to see if it's safe. It may be a new way to protect against certain infections.
Norfolk, VirginiaAges 18–45 - NCT07230652RecruitingPhase 1
Safety study of LY03020 for healthy volunteers and people with schizophrenia
This study tests the safety of a new medication called LY03020. It is for healthy volunteers and for people with stable schizophrenia. The study aims to see how well the body handles the drug and what side effects might occur.
BeijingAges 18–60 - NCT07248865RecruitingPhase 1
Study of CLYM116 in healthy volunteers
This study tests a new drug called CLYM116 in healthy adults to see how safe it is and how the body processes it. It may help researchers learn more before testing it in people with certain medical conditions.
BrisbaneAges 18–60 - NCT07275918RecruitingPhase 1
Study of SA1211 injection for chronic hepatitis B
This study tests a new injection called SA1211 for people with chronic hepatitis B. It will help see if the treatment is safe and how it works in the body.
Changchun, JilinAges 18–65 - NCT07284797RecruitingPhase 1
Safety study for autoimmune disease and healthy volunteers
This trial is testing an experimental drug for safety in people with certain autoimmune diseases—like myositis, scleroderma, or Sjögren's disease—as well as in healthy volunteers. It aims to find out if the drug is safe enough to study further.
MelbourneAges 18–75 - NCT07297173RecruitingPhase 1
Immune cell infusion plus transplant for tough leukemia
This trial tests a new two-step approach for people with hard-to-treat leukemia. First, you get chemotherapy plus an infusion of special immune cells from a partially matched donor, then a stem cell transplant. The goal is to see if this is safe and helps the leukemia go away.
BeijingAges 15 years+ - NCT07299955RecruitingPhase 1
Testing a new Herceptin shot in healthy men
This trial tests a new version of the breast cancer drug Herceptin (called Bmab3000) given as a single shot under the skin. It looks at how the drug moves through the body, its safety, and how the immune system responds, in healthy volunteers.
Christchurch, Main Building: 264 Antigua Street,Ages 18–65 - NCT07304791RecruitingPhase 1
Testing beam-103 safety in healthy volunteers
This trial tests a new drug called BEAM-103 in healthy people to see if it's safe and how the body processes it. It's a single-blind study, meaning you won't know if you get the drug or a placebo.
LondonAges 18–55 - NCT07306754RecruitingPhase 1
A Safety Study of ABBV-243 in Healthy Adults
This study tests a new drug called ABBV-243 in healthy adults to see if it is safe and how the body processes it. Participation helps researchers understand the drug before studying it in people with a disease.
Grayslake, IllinoisAges 18–60 - NCT07311993RecruitingPhase 1
Study of CLR 125 for triple negative breast cancer
This trial tests an experimental drug called CLR 125 in people with triple negative breast cancer that has worsened after at least one prior treatment. It aims to see if the drug is safe and how it affects the cancer.
Jacksonville, FloridaAges 18 years+ - NCT07317505RecruitingPhase 1
Study of JMT108 for Advanced Solid Tumors
This trial tests a new drug called JMT108 in people with advanced solid tumors that have not responded to standard treatments or for which no standard treatment exists. The study aims to see if the drug is safe and how it affects the body.
Huntersville, North CarolinaAges 18 years+ - NCT07330674RecruitingPhase 1
Safety study of ABF-101 in healthy people and AMD patients
This trial tests the safety of a new drug called ABF-101 in two groups: healthy volunteers (Part A and B) and people with age-related macular degeneration (AMD, Part C). If you join, you will help researchers understand how the drug affects the body and if it's safe enough to study further.
Dallas, TexasAges 18–50 - NCT07335913RecruitingPhase 1
Testing SBS-147 in healthy adults for safety
This study tests a new drug, SBS-147, in healthy adults to see if it's safe and how the body processes it. It may help find the right dose for future studies in people with certain conditions.
Cypress, CaliforniaAges 18–55 - NCT07343245RecruitingPhase 1
Investigating DW4421 with common pain relievers in healthy adults
This trial tests a new drug, DW4421, when taken together with three different NSAID pain relievers to see if it's safe and how they interact. It is for healthy adults who want to help research a new treatment option.
Cheongju-siAges 19–50 - NCT03802695RecruitingPhase 1
Orca-Q pill to help during stem cell transplant
This Phase 1 trial studies Orca-Q to see if it is safe and works when added around the time of an allogeneic (donor) stem cell transplant for certain blood cancers. If you qualify, the study may offer a new option for managing the transplant immune response.
Duarte, CaliforniaAges 12–78 - NCT07347171RecruitingPhase 1
Testing CG009301 for blood cancers that returned or didn't respond
This trial tests a new drug called CG009301 for people with blood cancers that have come back or haven't responded to standard treatments. The goal is to see if the drug is safe and works against these cancers.
NanchangAges 18–75 - NCT07357870RecruitingPhase 1
Cream study for facial vitiligo
This trial tests a new cream for vitiligo on the face or neck. It aims to see if the cream can help bring color back to white patches.
Ankara, TurkeyAges 18–60 - NCT07371338RecruitingPhase 1
Testing a new drug for advanced Parkinson's
This trial tests an investigational drug called IPS101A in people with advanced Parkinson's disease. It aims to see if the drug is safe and how well it works when standard treatments are no longer enough.
SeoulAges 50–80 - NCT07376707RecruitingPhase 1
Study of TGI-5 alone or with nivolumab for advanced solid tumors
This trial tests a new drug called TGI-5, either by itself or combined with another drug (nivolumab), for people with advanced cancer that hasn't responded to standard treatments. It's looking for patients with certain types of solid tumors, especially colorectal, melanoma, lung, or others that have stopped responding to therapy.
ShanghaiAges 18 years+ - NCT07382817RecruitingPhase 1
A study of CAR T cells for patients with certain T or NK cell cancers
This trial tests whether a new treatment, called CAR T cells that target CD94, can help people with specific types of T or NK cell lymphoma or leukemia that have not responded to other treatments or have come back. The goal is to see if it is safe and works against the cancer.
Houston, TexasAges 18 years+ - NCT07411755RecruitingPhase 1
Comparing a new biologic (GS101) with Dupixent in healthy volunteers
This trial tests a new biologic medicine (GS101) against an approved treatment (Dupixent) for conditions like atopic dermatitis. It is looking for healthy volunteers to compare how the body processes each drug after an injection under the skin.
Suzhou, JiangsuAges 18–55
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Common questions
- Are there clinical trials for phase 1?
- Yes. Clin2 currently lists 285 recruiting phase 1 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a phase 1 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a phase 1 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.