Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05955001RecruitingPhase 2/Phase 3
Tadalafil for early urinary symptoms after prostate surgery
This trial studies whether daily tadalafil (5 mg) can improve early urinary trouble and erection function after endoscopic prostate tissue removal. It may help men whose urinary symptoms continued even after prior medicine.
Al Mansurah, Dakahlia GovernorateAges 40–80 - NCT05955066RecruitingPhase 4
Testing a JAK inhibitor to help RA joint erosion heal
This Phase 4 study tests whether a JAK inhibitor (baricitinib) can improve how RA-related bone erosion heals. You might be eligible if you have rheumatoid arthritis that is still active despite methotrexate treatment, and you meet the specific safety and medication history rules.
Hong Kong, Hong KongAges 18–65 - NCT05955924RecruitingPhase 3
Nicotinamide to prevent skin cancer after organ transplant
This trial tests nicotinamide (a vitamin-like medicine) to help prevent new keratinocyte skin cancers in people who have had a kidney, liver, heart, or lung transplant. It may lower the chance of developing new skin tumors while you continue your usual transplant anti-rejection medicines.
Calgary, AlbertaAges 18 years+ - NCT05961059RecruitingPhase 1
Shigella vaccine safety study for healthy adults
This Phase 1 study tests a Shigella (gut infection) vaccine and additives to see how safe they are in healthy adults. If you qualify, you may help researchers understand whether the vaccine triggers any unwanted immune or stomach side effects.
LeidenAges 18–50 - NCT05961644RecruitingPhase 2/Phase 3
Cladribine vs placebo for non-active progressive multiple sclerosis
This trial tests whether cladribine (vs an inactive placebo pill) can slow disability worsening in people with a non-active, progressive form of multiple sclerosis. It may help by reducing the immune activity that can drive ongoing nerve damage, even without recent relapses.
Warsaw, Masovian VoivodeshipAges 30–65 - NCT05962840RecruitingPhase 4
Rituximab plus telitacicept for ANCA vasculitis
This Phase 4 trial studies whether rituximab combined with telitacicept works better and is safe for people with severe active ANCA-associated vasculitis (including certain subtypes like GPA or MPA). If you meet specific blood test and disease activity criteria, you may be considered to help lower inflammation and prevent flare-ups.
BeijingAges 18–65 - NCT05964387Recruiting
Silver fluoride treatment and local numbing for tooth cavities
This study tests whether applying silver diamine fluoride (a cavity-stopping liquid) changes how well local numbing works during dental treatment for certain tooth defects. It may help determine the safest and most comfortable way to treat weak, cavity-prone molars in children.
Ann Arbor, MichiganAges 6–11 - NCT05966064RecruitingPhase 4
Denosumab for adult fibrous bone lesions with ongoing pain
This trial studies denosumab to reduce pain and active bone disease in adults with fibrous dysplasia / McCune-Albright syndrome. You may be eligible if your FD/MAS is causing persistent pain and has signs of active bone turnover, despite adequate pain treatment.
LeidenAges 18 years+ - NCT05966649Recruiting
Synbiotics for preventing preterm birth in higher-risk pregnancies
This trial tests whether taking synbiotics (a mix of “good” probiotics and “food” for them) can help lower the chance of going into labor too early. It’s for pregnant people with certain risk factors for preterm birth, and it compares outcomes while you follow the study plan.
Edegem, AntwerpenAges 18 years+ - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70 - NCT05975983RecruitingPhase 2
Oral treatment test for idiopathic pulmonary fibrosis
This Phase 2 study tests whether an oral medication (INS018_055) can help people with idiopathic pulmonary fibrosis (IPF). You may be a fit if your lung function is in a certain range and your condition is stable.
Birmingham, AlabamaAges 40 years+ - NCT05976152RecruitingPhase 3
Butyphthalide to improve thinking after a recent stroke
This Phase 3 study tests whether butyphthalide can help thinking and memory improve after an acute ischemic stroke. It compares people who take the study medicine versus usual care, and measures cognitive (thinking) changes over follow-up.
Dandong, LiaoningAges 60 years+ - NCT05977023RecruitingPhase 2
NMDA-targeted medicine to treat bipolar I depression
This Phase 2 study tests a medication that works on NMDA receptors to improve depression symptoms in people with bipolar I disorder. It may help if you’re currently in a bipolar depression episode and other mood treatments haven’t fully controlled it.
TaichungAges 18–65 - NCT05978206RecruitingPhase 2
Strength, muscle mass, and nutrition therapy for older adults with sarcopenia
This study tests if a combination of a medicine (nandrolone), physical therapy, and a special diet can help older adults with muscle loss (sarcopenia) improve their strength and muscle mass. It is for people age 60 to 99 who have been diagnosed with sarcopenia based on specific muscle strength and mass measurements.
Warsaw, Masovian VoivodeshipAges 60–99 - NCT05978505RecruitingPhase 2
Reboxetine for sleep apnea after ENT surgery
This study tests if the medication reboxetine helps reduce sleep apnea symptoms after planned upper airway surgery. It may be a good fit if you have sleep apnea and are having surgery on your nose or throat.
Bedford Park, South AustraliaAges 18 years+ - NCT05979389RecruitingPhase 1
Bicalutamide for young women with PCOS and fatty liver
This trial tests a medicine called bicalutamide (an anti-androgen) to see if it can help young women with both PCOS and fatty liver disease (NASH). The goal is to find a new treatment option for these two conditions together.
San Francisco, CaliforniaAges 18–42 - NCT05985629RecruitingPhase 4
Numbing shot behind the knee for ACL surgery pain
This study tests whether an extra numbing shot (called IPACK) behind the knee helps reduce pain and the need for strong pain medicine after ACL reconstruction surgery. It's for patients who are having their first ACL surgery and are not using a donor graft.
Maywood, IllinoisAges 16 years+ - NCT05985863RecruitingPhase 1/Phase 2
Stem cell therapy for acute-on-chronic liver failure
This trial tests whether stem cells from donated umbilical cords can help people with acute-on-chronic liver failure, a sudden worsening of chronic liver disease. The goal is to see if this treatment improves liver function and survival.
Beijing, Beijing MunicipalityAges 18–70 - NCT05985850RecruitingPhase 2
Can cannabis help with opioid addiction treatment?
This trial tests if adding a specific cannabis product to standard methadone treatment helps people with opioid use disorder. It's for adults over 25 who recently started methadone and have used cannabis before.
Vancouver, British ColumbiaAges 25 years+ - NCT05991804Recruiting
Spinal cord stimulation to improve arm function after injury
This trial tests a treatment that uses mild electrical stimulation on the upper spine to help improve arm and hand function after a recent spinal cord injury. It is for people who are in the hospital and have injury levels between C1 and C8.
LondonAges 18 years+ - NCT05992311RecruitingPhase 1
Testing montelukast for gulf war illness
This study tests whether montelukast, a medication for asthma and allergies, can help improve thinking problems in veterans with Gulf War Illness. The trial involves taking the study drug or a placebo for 8 weeks, with weekly phone check-ins.
Houston, TexasAges 50–70 - NCT05995964RecruitingPhase 2
Study of two new medicines for eczema
This study tests two new study medicines (PF-07275315 and PF-07264660) for people with moderate to severe eczema that hasn't responded well to other treatments, including biologics. The goal is to see if these medicines can help reduce itching and clear the skin.
Birmingham, AlabamaAges 18 years+ - NCT05996627RecruitingPhase 2
Belumosudil for early treatment of chronic graft-versus-host disease
This trial tests a pill called belumosudil to see if it can help people with chronic graft-versus-host disease (a common complication after a stem cell transplant where donor cells attack your body). It is for patients who have symptoms but are not yet on strong immune-suppressing drugs.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,245 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.