Clinical trials
Pulmonary Disease, Chronic Obstructive (COPD) clinical trials
Below are recruiting pulmonary disease, chronic obstructive (copd) clinical trials, each written for real people, not researchers. We’re tracking 305 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT05572632Recruiting
COPD wellness rehab program for safety-net patients
This trial studies a COPD (chronic lung disease) wellness and rehabilitation program for people who get care through the safety-net health system. It may help improve day-to-day outcomes by supporting safer exercise and better COPD management.
San Francisco, CaliforniaAges 40–90 - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05704881Recruiting
Using breath CO2 levels to judge COPD flare severity in ER
This study measures an easy breathing signal called end-tidal carbon dioxide (a CO2 reading from your exhaled breath) to help judge how severe a COPD flare is. It may help doctors decide how closely you need monitoring and treatment during emergency care.
Grenoble, IsèreAges 18 years+ - NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT05437198Recruiting
Breath sample study comparing lung bacteria in and out of COPD
This study looks at the germs in exhaled (breathed-out) air to compare people with COPD to people without COPD. It may help researchers better understand lung differences and what could drive COPD.
CréteilAges 18–70 - NCT05399056Recruiting
Peer support and storytelling to help COPD lung rehab
This study aims to improve how well people with COPD can take part in pulmonary rehabilitation by using peer coaching and short storytelling videos. If you recently had a COPD flare and are being referred to lung rehab, this may offer extra support to help you complete the program.
Springfield, MassachusettsAges 40 years+ - NCT05265299RecruitingPhase 3
Testing the right aspirin dose for COPD symptoms
This Phase 3 trial studies which aspirin dose works best in people with COPD, with the goal of improving disease control. You may be asked to take aspirin and be monitored for safety, especially bleeding risk and heart/brain history.
Baltimore, MarylandAges 40–80 - NCT05297279Recruiting
Omega-3 diet program for people with COPD
This trial tests whether increasing omega-3 (from diet and/or supplements) helps people with COPD. It enrolls people with low omega-3 intake and asks them to follow a specific dietary plan during the study.
Baltimore, MarylandAges 40 years+ - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05196698Recruiting
Home high-flow oxygen after COPD hospital flare
This study tests whether using a special oxygen device at home helps prevent another acute COPD flare after you’ve been hospitalized. It’s mainly for people with severe breathing problems who may need oxygen support long-term.
RouenAges 18–85 - NCT05061368RecruitingPhase 2
Sildenafil by mouth to improve breathing in COPD
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
Edmonton, AlbertaAges 40–80 - NCT05008081Recruiting
Study for COPD flare-ups given standard rescue medicines
This study looks at people hospitalized for a COPD flare-up (“exacerbation”). It may help improve how flare-ups are treated because participants need to receive the usual rescue medicines like steroids and/or antibiotics and then follow a study plan.
LinzAges 18 years+ - NCT04849806Recruiting
Testing whether heart nerve signals predict COPD symptoms
This study looks at “sympathetic nerve activity” (signals from the nervous system that affect the heart) in adults with chronic obstructive pulmonary disease (COPD). The goal is to see whether these measurements can help predict what happens to people with COPD.
AachenAges 18 years+ - NCT04722835Recruiting
Study lung immune cells in people at risk for COPD
This study looks at different lung immune cell patterns and how they work in smokers who are not yet diagnosed with COPD or asthma. It may help researchers understand why some people are more likely to develop COPD, which could guide future prevention or early treatments.
San Francisco, CaliforniaAges 40–75 - NCT04427826RecruitingPhase 1/Phase 2
Morphine to prevent early NIV failure in COPD flare-ups
This trial studies whether morphine can help people with a COPD flare-up avoid “non-invasive ventilation” (breathing support through a mask) failing early. The goal is to reduce how often people need escalation of care soon after starting NIV.
Grenoble, Isère, Auvergne-Rhône-AlpesAges 18 years+ - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT03799354Recruiting
Strength training study for people with COPD
This trial tests whether a maximal strength training program can help people with COPD who are stable. It is looking at people with moderate-to-severe airflow limitation and excludes several other lung and health problems.
Lumezzane, BresciaAges 50–80 - NCT02777879Recruiting
Study gut-like lung bacteria and inflammation in early COPD
This study looks at the lung’s tiny bacteria (microbiome) and inflammation in people with early COPD who have a smoking history. It compares them with smokers who have normal breathing tests, to better understand what may drive COPD early on.
New York, New YorkAges 18–70 - NCT03044847Enrolling by invitation
Long-term study of COPD in adults in China
This study follows people with COPD (chronic lung disease) over many years to better understand the condition. It may help doctors learn what factors predict worsening over time.
Beijing, Beijing MunicipalityAges 40–75 - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT00307281Recruiting
Emphysema and COPD patient registry with sample storage
This study enrolls people who have emphysema/COPD into a research registry and collects health information and biological samples. It may help researchers understand the disease better and improve future treatments.
Pittsburgh, PennsylvaniaAges 21 years+ - NCT06090838Recruiting
Balloon angioplasty for blood clots in the lungs after pulmonary embolism
This trial tests whether balloon angioplasty can improve breathing and exercise ability in people who still have symptoms and blood flow problems 3 months or more after a pulmonary embolism. It is for those who have completed a pulmonary rehabilitation program.
Amsterdam, North HollandAges 18–80
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Common questions
- Are there clinical trials for pulmonary disease, chronic obstructive (copd)?
- Yes. Clin2 currently lists 305 recruiting pulmonary disease, chronic obstructive (copd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary disease, chronic obstructive (copd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary disease, chronic obstructive (copd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.