Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05784428Recruiting
Comparing one versus multiple radiation treatments for cancer that has spread
This trial tests whether giving one strong dose of radiation is as good as several smaller doses for people with a small number of cancer spots that have spread. The goal is to find a treatment that is just as effective but more convenient and with fewer side effects.
Kelowna, British ColumbiaAges 18 years+ - NCT05765812RecruitingPhase 1/Phase 2
Debio 0123 with temozolomide for recurrent or new glioblastoma
This early-phase study tests Debio 0123 (an anticancer medicine) combined with temozolomide, and for newly diagnosed patients also with radiation. It aims to see whether this treatment combination can slow or control glioblastoma in adults.
Chicago, IllinoisAges 18 years+ - NCT05774275RecruitingPhase 1/Phase 2
Testing combined radiation, chemotherapy, and immunotherapy for high-risk sarcoma
This study tests whether giving radiation, chemotherapy, and immunotherapy together can control high-risk soft tissue sarcoma that is hard to remove or may come back after surgery. It may help by attacking cancer in different ways, including boosting the immune system.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04570943RecruitingPhase 2
Pancreatic cancer treatment: chemo first, then targeted MRI-guided radiation
This Phase 2 trial tests giving specific chemotherapy in sequence, then using MRI-guided focused radiation to treat locally advanced, non-removable pancreatic cancer. It may help shrink or control the tumor while aiming radiation more precisely using MRI.
Marseille, Bouches-du-RhôneAges 18–75 - NCT05656794RecruitingPhase 2
Radiation after treatment for prostate cancer that has spread
This trial studies whether adding a targeted course of radiation to the prostate area after initial systemic treatment can improve outcomes for people with metastatic prostate cancer. It may help control the cancer by treating remaining disease after medicines have started working.
Toronto, OntarioAges 18–100 - NCT05552846Recruiting
Radiation to the chest after chemo-immunotherapy for small cell lung cancer
This trial looks at whether giving additional targeted radiation to the chest can help people with extensive-stage small cell lung cancer after they finish standard chemo-immunotherapy. It may help control the cancer in the lung area and prevent it from coming back there.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05534321RecruitingPhase 1/Phase 2
Preventive radiation for high-risk spinal bone metastases
This trial tests whether preventive (before serious problems happen) radiation to the spine can help people with high-risk, mostly symptom-free bone metastases. It may reduce the chance of pain escalation or dangerous complications from cancer in the spine.
Miami, FloridaAges 18 years+ - NCT05479409RecruitingPhase 2
Radiation before surgery for advanced breast cancer
This trial tests whether giving radiation therapy before surgery helps people with locally advanced breast cancer that hasn't been removed with chemotherapy. It may offer a new option for those who cannot have surgery right away.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05439031RecruitingPhase 2
Stereotactic radiation to reduce recurrent dangerous heart rhythm episodes
This Phase 2 study tests a precise form of radiation therapy to control recurrent ventricular tachycardia (VT), a dangerous fast heart rhythm. It may help people whose VT keeps coming back despite heart medicines and/or ablation, especially when ablation is not possible.
Amsterdam, North HollandAges 18 years+ - NCT05457699RecruitingPhase 2
Targeted radiation to control prostate cancer spread
This Phase 2 study tests whether a focused form of radiation given after your cancer responds to medicine can help keep metastatic prostate cancer under control. It may help by “consolidating” your current good response, potentially delaying progression.
Montreal, QuebecAges Any age - NCT04550104RecruitingPhase 1
Durvalumab with radiation for lung cancer patients
This trial tests adding durvalumab (an immune therapy) to a radiation treatment plan for people with non-small cell lung cancer (NSCLC) who can’t safely have chemotherapy at the same time or surgery first. It aims to improve cancer control after radiation by helping the immune system recognize and fight the tumor.
BelfastAges 18 years+ - NCT05338866Enrolling by invitation
Chemo plus targeted high-dose radiation for low rectal cancer
This trial tests whether combining chemotherapy with high-dose radiation guided by MRI (a special scan) can better treat low rectal cancer. It may help shrink the tumor and improve local control while targeting the tumor more precisely.
Guangzhou, GuangdongAges 18–80 - NCT05328505Recruiting
Imaging-guided radiation for prostate cancer that came back
This trial tests whether a special scan (PSMA PET) can help doctors aim and adjust radiation more precisely when prostate cancer returns after surgery. It may help by increasing dose to areas that look involved while lowering dose to uninvolved pelvic areas.
London, OntarioAges 18 years+ - NCT05277688RecruitingPhase 3
Radiation alone versus added chemotherapy after cervical cancer surgery
This trial compares standard radiation to radiation plus chemotherapy after surgery for early-stage cervical cancer. It aims to lower the chance the cancer comes back in patients considered higher risk based on their surgical pathology.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05124236Recruiting
Pre-surgery vs post-surgery focused radiation for brain metastases
This trial compares two ways of giving focused radiation for brain metastases: before surgery or after surgery. It aims to see which timing works better to control tumors while keeping you safe.
InnsbruckAges 18 years+ - NCT05102747Recruiting
Surgery-like brain radiation for up to 5 metastases
This trial compares two ways of giving focused radiation to the brain for people with a limited number of brain metastases. It aims to see which schedule works best (and is likely best for costs and quality of life).
BordeauxAges 18 years+ - NCT04944914RecruitingPhase 3
Camrelizumab with targeted radiation for limited nasopharyngeal cancer spread
This trial tests whether combining camrelizumab (an immune medicine) with stereotactic body radiotherapy (high-precision radiation) works better than camrelizumab alone. It’s for people whose nasopharyngeal cancer has spread to a small number of spots in the body and may help control those metastases longer.
Guangzhou, GuangdongAges 18–70 - NCT04986293Recruiting
CPAP or BiPAP to reduce motion during radiation
This study tests whether using a breathing machine (CPAP or BiPAP) can help keep you still during radiation treatment. This may improve how accurately radiation is delivered for certain cancers treated with curative intent.
Groningen, Provincie GroningenAges 18 years+ - NCT04889924Recruiting
Lymph node surgery vs radiation after chemo for breast cancer
This trial compares two ways to treat the underarm lymph nodes in people whose sentinel lymph node still shows limited cancer after chemotherapy and hormone treatment. It may help find which approach controls cancer better with fewer side effects.
Sydney, New South WalesAges 18 years+ - NCT04095299RecruitingPhase 3
Standard vs high-dose radiotherapy for rectal cancer
This Phase 3 trial compares standard-dose and higher-dose radiotherapy given along with chemotherapy in people with rectal cancer. The goal is to see whether a higher dose can improve rectal cancer outcomes while keeping the rectum functioning and avoiding too much harm.
AalborgAges 18 years+ - NCT04843683Recruiting
Stereotactic radiation treatment for abnormal heart rhythms
This trial studies using a precise type of radiation (stereotactic ablative radiotherapy) to treat abnormal heart rhythms when medicines or prior procedures haven’t worked. It may help by targeting the heart area causing the rhythm problem without doing another invasive ablation.
Toronto, OntarioAges 18 years+ - NCT04746729Recruiting
Using past radiation records to study heart and lung effects in kids
This study looks back at children’s radiation treatments to understand long-term heart and lung side effects from modern radiotherapy. It may help doctors better plan safer radiation for future patients.
LeuvenAges Up to 22 years - NCT04722263Recruiting
Radiation treatment for raised scar tissue (keloids)
This study tests how radiation (RT) can treat keloids, especially when surgery is not possible or you choose not to do surgery. The goal is to see if radiation can safely improve or control the keloid.
The Bronx, New YorkAges 18 years+
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,308 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.