Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,309 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06272214RecruitingPhase 2
Adjuvant radiotherapy for esophageal cancer after immunotherapy
This trial tests if adding radiation therapy after surgery improves outcomes for people with esophageal squamous cell cancer who received immunotherapy and chemotherapy before surgery but did not achieve a complete response. It aims to see if this approach can lower the chance of the cancer coming back.
Hangzhou, ZhejiangAges 18–75 - NCT06297902Recruiting
PET-guided Radiation for Head and Neck Cancer
This trial tests a new way to give radiation therapy for head and neck cancer. By using a special PET scan to guide where higher radiation doses are given, doctors hope to improve treatment while reducing side effects. It is for people whose cancer is not early-stage and who will receive standard radiation therapy.
BergenAges 18 years+ - NCT06311968RecruitingPhase 2
Proton radiation after surgery for thymus tumors
This trial tests a type of precise radiation called proton therapy after surgery for thymus tumors. It may help reduce the chance of the tumor coming back while limiting side effects to nearby organs.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06321653Recruiting
Lymphedema after radiation for early breast cancer with 1-2 positive nodes
This trial aims to see if a shorter course of radiation after breast-conserving surgery affects arm swelling (lymphedema) in people with early breast cancer that has spread to 1 or 2 nearby lymph nodes. The goal is to learn if this approach is safe and effective.
MilanAges 18 years+ - NCT06353685RecruitingPhase 2
Less radiation after surgery for oral cancer with good response
This trial is testing whether giving less radiation after surgery is safe and effective for people with oral cancer whose surgery results were very good (no cancer cells or very few left). It aims to reduce side effects while still preventing cancer from coming back.
GuangzhouAges 18–80 - NCT06356584RecruitingPhase 2
A drug combination with or without radiation for advanced colorectal cancer
This trial tests a new drug combo (fruquintinib and sintilimab) with or without radiation for people with colorectal cancer that has spread to the liver and has not responded to earlier treatments.
Jinan, ShandongAges 18–75 - NCT06418113RecruitingPhase 1
Radiation and chemo before surgery for glioblastoma
This trial tests giving radiation and chemotherapy before surgery for glioblastoma. It aims to see if this approach is safe and may help improve outcomes for patients whose tumor can be completely removed.
MadridAges 18–75 - NCT06487403Recruiting
Delaying radiation for head and neck cancer: MRI and immune markers study
This study tests whether delaying radiation therapy can help doctors learn more from MRI scans and immune system changes in patients with head and neck cancer. This could lead to better treatment decisions.
Toronto, OntarioAges 18 years+ - NCT06501053Recruiting
Contact X-ray therapy for early rectal cancer
This trial tests a special type of contact X-ray (brachytherapy) for early-stage rectal cancer. It may help avoid major surgery by treating the tumor from inside the rectum.
Stockholm, SolnaAges 18 years+ - NCT06516133RecruitingPhase 3
Online adaptive radiotherapy for nasopharyngeal cancer
This trial tests a new type of radiation therapy that adjusts in real-time to treat nasopharyngeal cancer. It is for people who have not received prior radiation and have no distant spread of cancer.
Guangzhou, GuangdongAges 18–70 - NCT06529081Recruiting
Radiation schedule for advanced small-cell lung cancer after chemo-immunotherapy
This study tests a specific radiation schedule (15 sessions to the chest and up to 3 sessions to other spots) for people with advanced small-cell lung cancer that responded to first-line chemo combined with immunotherapy. The goal is to see if this radiation approach can improve control of the disease.
LublinAges 18 years+ - NCT06533267Recruiting
Endoscopic surgery vs. radiation for early-stage nasal cancer
This trial compares two treatments for stage I nasopharyngeal cancer (a type of nasal cancer). It tests whether a minimally invasive surgery (endoscopic surgery) is as good as or better than radiation therapy. It may be an option for people whose cancer is small and hasn't spread to lymph nodes.
Zhuhai, GuangdongAges 18–75 - NCT06542159RecruitingPhase 2
Adaptive radiation for early-stage lung cancer or small metastases
This trial tests a more precise radiation technique (stereotactic body radiotherapy) for early-stage lung cancer or small lung tumors. It aims to reduce side effects by eliminating the usual safety margin around the tumor.
Guangzhou, GuangdongAges 18 years+ - NCT06607406Recruiting
Timing of radiation after surgery for head and neck cancer
This study tests whether starting radiation therapy more than 6 weeks (but within 16 weeks) after surgery is safe and effective for people with certain high-risk head and neck cancers. It could help those who had to delay radiation for recovery or other reasons.
Charlotte, North CarolinaAges 18 years+ - NCT06625970RecruitingPhase 3
Darolutamide and high-dose radiation for high-risk prostate cancer
This trial tests a combination of a hormone therapy pill (darolutamide) and a high-dose, precise form of radiation for men with localized prostate cancer that has high-risk features of coming back. The goal is to see if this approach is more effective than standard treatment.
BrestAges 18–80 - NCT06650033Recruiting
Pelvic adaptive radiotherapy study
This trial tests a special type of radiation called adaptive radiotherapy for people with certain pelvic cancers. Adaptive radiotherapy adjusts the treatment plan each day based on changes in your body, which may help target the cancer more precisely and reduce side effects.
St Leonards, New South WalesAges 18 years+ - NCT06688760Recruiting
Surgery vs surgery plus lower-dose radiation for early nasopharyngeal cancer
This trial compares two treatments for newly diagnosed Stage I nasopharyngeal cancer: surgery alone versus surgery followed by a lower dose of radiation. The goal is to see if adding a gentler radiation dose can prevent the cancer from coming back without too many side effects.
Guangzhou, GuangdongAges 18–70 - NCT07686016Recruiting
Radiation therapy for prostate cancer that has spread to a few spots
This trial studies the use of radiation to the prostate and to all visible spots where cancer has spread, in men who have up to 10 small areas of spread when first diagnosed. The goal is to see if this approach can help control the cancer.
Zamość, Lublin VoivodeshipAges 18 years+ - NCT06719440Recruiting
Better outcome by shrinking radiation target for glioblastoma
This trial tests a smaller radiation target for newly diagnosed glioblastoma to reduce side effects while keeping treatment effective. It may help patients who are healthy enough for standard chemoradiotherapy.
AalstAges 18 years+ - NCT06740955Recruiting
Shorter radiation course for newly diagnosed glioblastoma
This trial tests a shorter, more intense course of radiation therapy (hypofractionated radiotherapy) for people with newly diagnosed glioblastoma who have had surgery. The goal is to see if this approach is safe and works well for treating the tumor.
Changchun, JilinAges 18–70 - NCT06752239RecruitingPhase 3
Optimizing radiation to protect thyroid in nasopharyngeal cancer
This trial tests a way to adjust radiation therapy to better protect the thyroid gland during treatment for nasopharyngeal carcinoma. It aims to reduce thyroid damage while still effectively treating the cancer.
Nanchang, JiangxiAges 18–70 - NCT06765616RecruitingPhase 2
Immunotherapy with chemo and radiation for rectal cancer before surgery
This trial tests a combination of a PD-L1 inhibitor (adebrelimab), short-course radiation, and chemotherapy given before surgery for locally advanced rectal cancer. The goal is to see if this approach can shrink the tumor and improve outcomes.
Jinan, ShandongAges 18–85 - NCT06775678RecruitingPhase 2
Spatial fragmentation plus low-dose radiation for resistant lung cancer
This study tests whether combining a special type of radiation (spatial fragmentation) with low-dose radiation can help people whose lung cancer stopped responding to immunotherapy and chemotherapy. If you are eligible, you may receive a new treatment approach to try to shrink the tumors.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06831773Recruiting
Carbon ion radiation for high-grade brain tumors
This trial tests a precise type of radiation called carbon ion radiotherapy for people with aggressive brain tumors (high-grade gliomas). It aims to see if this treatment is safe and effective for patients who have not had radiation to the head before.
Wuwei, GansuAges 14–80
Hear when a new Radiotherapy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,309 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.