Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,309 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01985984Recruiting
Predicting outcomes after head and neck radiotherapy
This study looks at how outcomes may be predicted for people with head and neck cancer who receive radiotherapy. It may help doctors better estimate results and tailor follow-up care.
MaastrichtAges 18 years+ - NCT00026650Recruiting
Understanding Long-Term Effects After Radiation Therapy
This study follows patients who have received radiation therapy to learn about long-term health effects and how the disease progresses over time. By tracking your health over the years, researchers hope to better understand and help future patients manage side effects.
Bethesda, MarylandAges 18–120 - NCT01803542RecruitingPhase 2
Stereotactic radiation for lung metastases or early lung tumors
This trial studies a precise, high-dose radiation technique (SBRT) to treat tumors in the lungs. It may help control cancer in people who either have early-stage lung cancer that is not fully operable or have limited lung metastases from other cancers.
Toronto, OntarioAges 18 years+ - NCT01786590Recruiting
Ultrasound biopsy to stage lung cancer before SBRT
This trial looks at using a scope with an ultrasound tip (EBUS-TBNA) to take small tissue samples from lymph nodes to figure out the cancer stage before stereotactic body radiotherapy (SBRT). The goal is to help confirm how far the cancer has spread so SBRT can be planned appropriately.
Toronto, OntarioAges 18 years+ - NCT02016248Recruiting
Radiation “boost” for higher-risk prostate cancer
This trial studies whether adding a stronger “boost” dose of targeted radiation (SBRT) can better control higher-risk prostate cancer. It may help by increasing radiation coverage to the prostate while trying to limit treatment to surrounding areas.
Fountain Valley, CaliforniaAges 18 years+ - NCT00969111Recruiting
Radiation after prostate surgery for prostate cancer without nodal spread
This trial looks at radiation therapy given after prostate surgery (or if needed later) for prostate cancer where lymph nodes were not involved. It may help patients whose PSA rises or who need additional treatment to reduce the chance the cancer comes back.
Little Rock, ArkansasAges 18 years+ - NCT01284153Recruiting
Testing breast cancer radiation plans in a prone position
This study compares how well radiation treatment plans can be made when you lie face-down (prone) for breast cancer. It’s a planning study, meaning the main goal is to improve treatment planning and potential safety/comfort.
LeuvenAges Any age - NCT01185132RecruitingPhase 3
IMRT versus partial-breast radiation after lumpectomy
This study compares two different ways of giving radiation to the breast after lumpectomy for early-stage breast cancer. It may help determine which approach controls the cancer well while reducing radiation to surrounding healthy tissue.
Aurora, ColoradoAges 40 years+ - NCT01766297RecruitingPhase 2
Proton radiation after lumpectomy for early breast cancer
This trial studies a type of radiation made with protons to treat only part of the breast after surgery (lumpectomy) for early-stage breast cancer. It may help control the cancer while aiming to reduce radiation to surrounding tissues.
Scottsdale, ArizonaAges 50 years+ - NCT01649830RecruitingPhase 3
Temozolomide after radiation for low-grade brain tumor
This trial tests whether adding temozolomide chemotherapy after radiation helps control a type of low-grade brain tumor that was not fully removed. It may help reduce the chance the tumor comes back, compared with standard post-radiation care.
Guangzhou, GuangdongAges 18–60 - NCT02128906RecruitingPhase 2
Radiation plus chemo choices for throat cancer, using a tumor marker
This trial compares two treatment combinations given with radiation for certain cancers of the throat. It also uses a lab test on the tumor (ERCC1) to help choose and study which treatment works better.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT02454790Recruiting
Follow-up program for people with esophageal cancer
This trial tests a standard follow-up plan for people who have esophageal cancer and received a certain amount of radiation. It may help your care team monitor side effects and catch health changes early.
GroningenAges 18 years+ - NCT02435576Recruiting
Standard follow-up program for head and neck cancer patients
This trial sets up a standard schedule for follow-up visits for people receiving curative (aimed at cure) or after-surgery radiotherapy for head and neck cancer. It may help you stay on track with regular check-ins and early management of side effects or signs of recurrence.
GroningenAges 18 years+ - NCT02504788Recruiting
Protect the brain’s memory area during whole-brain radiation
This study tests whether avoiding the hippocampus (a part of the brain important for memory) during whole-brain radiotherapy can slow down thinking and memory decline. It may help some people preserve neurocognitive function while still treating brain metastases.
TaoyuanAges 18–84 - NCT02457962Recruiting
Registry study of outcomes from Mayo radiation treatments
This study collects information about how patients do after radiation treatment and stores some biological samples for future research. It includes people treated at Mayo Clinic Rochester for a cancer-focused (curative) course of radiation.
Rochester, MinnesotaAges Any age - NCT02290145RecruitingPhase 2
Study of Cyclin D1–targeted chemotherapy before oral cancer surgery
This Phase 2 trial tests a chemotherapy plan given first (before surgery) for people with oral squamous cell carcinoma that has specific cancer markers and lymph node involvement. It aims to shrink or control the cancer so treatment after may work better.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT02468024RecruitingPhase 3
Surgery or focused radiation for early lung cancer
This study compares two treatments—removing only part of the lung (sublobar resection) versus a focused radiation approach (stereotactic ablative radiotherapy)—for early-stage non-small cell lung cancer. It aims to see which option works better with fewer problems for the right patients.
La Jolla, CaliforniaAges 18 years+ - NCT02541435Recruiting
Breast cancer radiotherapy side effects study
This study looks at heart and blood-vessel side effects after modern radiation treatment for breast cancer, both soon after and years later. It may help doctors understand who is at risk and how to monitor heart health over time.
ÅlesundAges 30–70 - NCT02824731Recruiting
Proton vs photon radiation for certain brain tumors
This study compares two types of radiation—protons and photons (X-rays)—for specific brain tumors or tumor returns. It aims to see which approach works best and is safest for you, based on how much and where the radiation is delivered.
DresdenAges 18 years+ - NCT02945579Recruiting
Testing skipping breast surgery or radiation for top responders
This trial studies whether some people with early-stage breast cancer who respond extremely well to hormone/chemo/targeted treatment can safely skip breast surgery and/or radiation. It aims to reduce side effects without increasing cancer risk in carefully selected patients.
Gilbert, ArizonaAges 30 years+ - NCT03051464RecruitingPhase 2/Phase 3
Testing two ways to boost radiation to prevent rectal surgery
This study looks at whether two different added “boosts” of radiation can work as well for rectal cancer patients, aiming to avoid or reduce the need for rectal cancer surgery. You would receive a specific combination of radiation (including brachytherapy) and chemotherapy, and your tumor’s location and size will determine if you can take part.
Dallas, TexasAges 18–80 - NCT07527689Recruiting
Faster vs. Standard Radiation After Breast Cancer Surgery
This study compares two radiation schedules for breast cancer patients at high risk of cancer returning in lymph nodes. Both use modern radiation therapy, but one delivers treatment faster (ultra-hypofractionated) while the other uses a more moderate schedule. The goal is to see which approach works better with fewer side effects.
ShanghaiAges 18 years+ - NCT07400809Recruiting
Cervical cancer with limited spread: a study on treatment results
This study looks at women with cervical cancer that has spread to only a few places (oligo-metastatic) or come back in a few places (oligo-recurrent). It hopes to understand how well treating those spots with radiation or other local treatments works, even if you've already had treatment before.
Mumbai, MaharashtraAges Any age - NCT07407608Recruiting
Radiation therapy for unfavorable prostate cancer
This trial tests a type of focused radiation therapy for men with intermediate or high-risk prostate cancer that hasn't spread. It aims to improve outcomes by targeting the main tumor seen on MRI.
Monza, MBAges 18–90
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,309 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.