Clinical trials
Recurrence clinical trials
Below are recruiting recurrence clinical trials, each written for real people, not researchers. We’re tracking 1,383 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05487092Recruiting
Letrozole to help prevent endometrioma coming back after surgery
This study tests whether taking letrozole after laparoscopic ovarian cyst surgery can lower the chance that an endometrioma (a type of ovarian endometriosis cyst) comes back. It may help some people reduce recurrence after the cyst is removed.
Hong KongAges 18–45 - NCT06413992RecruitingPhase 2
Camrelizumab plus fluzoparib for TP53-mutated endometrial cancer
This trial tests a combination of two drugs, camrelizumab (an immunotherapy) and fluzoparib (a PARP inhibitor), for people with a specific type of endometrial cancer that has a TP53 gene mutation. It may offer a new option for advanced or recurrent disease after limited prior treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05866783Recruiting
Blood test to predict cancer coming back after liver transplant
This study uses a blood test (looking at sugars in the blood) to help predict whether liver cancer will come back after a liver transplant. It may help doctors monitor you more accurately and earlier if cancer returns.
GhentAges 18 years+ - NCT07851636Recruiting
Fast genetic testing to guide treatment for rare brain tumors
This trial tests a new way to pick treatments for rare brain tumors that have come back. Doctors will quickly analyze your tumor's genes and test drugs in the lab to find the best option for you.
Washington D.C., District of ColumbiaAges Up to 45 years - NCT04905810RecruitingPhase 2
Azacitidine or decitabine plus venetoclax for AML after prior failure
This trial studies whether adding venetoclax to either azacitidine or decitabine can treat acute myeloid leukemia (AML) when earlier “hypomethylating” treatment has stopped working. You might be a candidate if you’ve already tried azacitidine or decitabine for a related blood condition and it failed, and you meet the health-safety limits.
Clovis, CaliforniaAges 18 years+ - NCT03349762Recruiting
Huaier granules to help prevent colorectal cancer coming back
This study tests whether Huaier granules after surgery can lower the chance that colorectal cancer returns or spreads. It is for people who have recently had “radical” (complete) surgery for certain stages of colorectal cancer and are within about 2 months of that surgery.
Shijiazhuang, HebeiAges 18–75 - NCT06441110RecruitingPhase 3
BCG instillation for medium- to high-risk bladder cancer
This trial tests whether a specific schedule of BCG (a weakened germ that boosts the immune system) placed directly into the bladder is safe and effective for medium- to high-risk bladder cancer that hasn't grown into the muscle. It aims to see if adjusting the standard BCG course can work better for people with a PD-L1-positive tumor.
Fuzhou, FujianAges 18–75 - NCT06445803RecruitingPhase 1
CAR-T therapy for adults with certain blood cancers
This trial tests a type of immunotherapy called CAR-T cells that target two proteins (CD19 and CD22) on cancer cells. It may be an option for adults with B-cell acute lymphoblastic leukemia (ALL) or B-cell non-Hodgkin lymphoma (NHL) that has come back or not responded to earlier treatments.
Nanchang, JiangxiAges 18 years+ - NCT07840092Recruiting
Blood and tissue markers for liver cancer treatment response
This study looks at blood and tissue samples from people with liver cancer to find markers that can predict how well treatment works and whether the cancer might come back. It may help doctors personalize treatment and follow-up care.
TianjinAges 18 years+ - NCT07839767Recruiting
Personalized treatment to prevent liver cancer recurrence
This study uses a 3D-printed model of your liver tumor to help doctors choose treatment that may prevent the cancer from coming back after surgery. The model predicts how your tumor might respond, so you get the most effective therapy.
Hong KongAges 18 years+ - NCT07831369RecruitingPhase 2
Drug combination for recurrent glioma
This trial tests a combination of three drugs—valproic acid, irinotecan, and simvastatin—to see if they can help people whose brain tumor (glioma) has come back despite earlier treatment. The goal is to slow or stop tumor growth.
Fairfax, VirginiaAges 18–98 - NCT06359275RecruitingPhase 2
Combination therapy for locally advanced or recurrent pancreatic cancer
This trial tests a combination of immunotherapy (PD-1), chemotherapy, and a special type of radiation called PULSAR for patients with locally advanced pancreatic cancer or cancer that has come back only in the pancreas area. The goal is to see if this approach can shrink tumors or keep them from growing.
ShanhaiAges 18–75 - NCT06086197RecruitingPhase 2
A drug combo for early relapsed or refractory DLBCL
This trial tests a combination of chemotherapy drugs for people with a type of lymphoma called diffuse large B-cell lymphoma that has either come back early or never fully responded to first treatment. The goal is to see if this drug combination can help control the lymphoma.
Hangzhou, ZhejiangAges 18 years+ - NCT05410717RecruitingPhase 1
CAR-NK cell therapy for certain solid tumors
This early-phase trial tests a lab-made immune cell treatment for advanced solid tumors that show specific targets (including Claudin 6, GPC3, Mesothelin, or AXL). It may help the immune system better recognize and kill tumor cells, but eligibility depends on test results and your overall health.
Guangzhou, GuangdongAges 18–75 - NCT05352178RecruitingPhase 3
Targeted treatment for few-spread prostate cancer spots
This Phase 3 trial tests whether treating only a small number of prostate cancer metastases can help people with “oligorecurrent” (limited repeat) prostate cancer. It may reduce cancer activity while avoiding broader whole-body treatment for some patients.
LeuvenAges 18 years+ - NCT06205862RecruitingPhase 2
Fecal transplant for preventing colon polyp return
This study tests whether taking capsules of healthy bacteria (fecal microbiota transplant) can help prevent colon polyps from coming back after they have been removed. It might be an option for people who have had an adenoma polyp removed and want to reduce the chance of recurrence.
Guangzhou, GuangdongAges 18–75 - NCT06498622RecruitingPhase 2
Liver cancer relapse prevention after surgery
This trial tests a combination of two drugs (Donafenib and Envafolimab) after surgery to lower the risk of liver cancer coming back in people who have high-risk features. It may help if you qualify based on your tumor(s) and overall health.
Fuyang, AnhuiAges 18–80 - NCT05855811RecruitingPhase 2
Preventing a Second Cancer After Your First Cancer
This Phase 2 trial tests dostarlimab, an immune-based medicine, to help lower the chance of getting a second (new) cancer after treatment for a first solid tumor. It’s for people with higher risk features, and it aims to see whether the drug can prevent or delay second cancers.
CaenAges 18 years+ - NCT07807163RecruitingPhase 2
Study of ficerafusp alfa with pembrolizumab for head and neck cancer
This study tests a new drug called ficerafusp alfa combined with pembrolizumab (an immunotherapy) in people with head and neck cancer that has returned or spread. The drug targets a protein that may help the immune system fight the cancer. The study is comparing two different schedules of giving the drug to see which is better.
Fort Myers, FloridaAges 18 years+ - NCT07795034RecruitingPhase 2
Boron neutron therapy for recurrent head and neck cancer
This trial tests a new type of radiation therapy (boron neutron capture therapy) combined with two drugs for people whose head or neck cancer has returned and standard treatments have failed. It aims to see if this combination can shrink tumors and is safe.
Xiamen, FujianAges 18–75 - NCT07799519RecruitingPhase 2
Finerenone after heart procedure to lower atrial fibrillation return
This trial tests whether taking finerenone after a heart procedure to fix irregular heartbeat can help prevent atrial fibrillation from coming back. It's for people having their first such procedure and aims to improve long-term heart rhythm health.
TainanAges 18–80 - NCT04725422Recruiting
Registry for children with nonbacterial bone inflammation
This study collects medical information (and imaging results) from children and teens with nonbacterial bone inflammation. It may help doctors better understand how this condition looks on scans and how it’s diagnosed, especially to rule out infection or cancer.
Seattle, WashingtonAges Up to 21 years - NCT04257487RecruitingPhase 3
Sulodexide to prevent blood clots from coming back
This study tests sulodexide (a blood-vessel protective medicine) to help stop deep leg blood clots or lung clots from returning after you’ve already been treated. It may help people with higher bleeding risk who are taking or recently finished standard anticoagulant medicines.
RozzanoAges 75 years+ - NCT06524245Recruiting
Predicting Colorectal Cancer Recurrence with Portal Vein Blood
This study looks at blood from a special vein near your liver (portal vein) to find markers that might predict if colorectal cancer will come back. The goal is to create a better way to identify patients who may need closer monitoring after surgery.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for recurrence?
- Yes. Clin2 currently lists 1,383 recruiting recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.