Clinical trials
Renal Replacement Therapy clinical trials
Below are recruiting renal replacement therapy clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06229990RecruitingPhase 4
Using furosemide stress test to stop kidney replacement therapy
This study tests whether a furosemide (a water pill) stress test can help doctors decide when to safely stop continuous kidney replacement therapy in ICU patients with severe acute kidney injury. It may allow you to come off the machine sooner if your kidneys respond well.
Chiang MaiAges 20 years+ - NCT03329313RecruitingPhase 2
Adjusting dialysis salt levels for ICU kidney injury
This study tests whether using a specific salt (sodium) level in the dialysis fluid affects outcomes for adults in the ICU with sudden kidney failure. It may help your care team optimize dialysis settings during acute kidney injury.
Montpellier, MontpellierAges 18–80 - NCT03629977Recruiting
Timing dialysis in critically ill ICU patients
This study looks at the best timing for starting kidney support treatment (dialysis) in very sick people in the ICU. It may help improve outcomes by comparing different start times.
StockholmAges 18 years+ - NCT04705896RecruitingPhase 4
Albumin for kidney recovery after ICU kidney injury
This trial tests whether giving albumin (a blood protein through an IV) can improve recovery after acute kidney injury in people who are in the ICU and need kidney support treatment. It mainly aims to help the kidneys bounce back better after this serious illness.
Calgary, AlbertaAges 18 years+ - NCT05399537RecruitingPhase 3
Testing citrate fluid safety during kidney filtration (CRRT)
This Phase 3 study checks whether Prismocitrate 18 is safe for adults who need a kidney filtration treatment called CRRT. It is mainly for people who cannot safely use heparin (a common blood thinner) due to bleeding risk.
Birmingham, AlabamaAges 18 years+ - NCT05738330Recruiting
Symptom reporting during hemodialysis care
This study looks at how well a new phone or computer system can help people on hemodialysis report their symptoms. It may improve symptom tracking so clinics can better understand and respond to what you feel during treatment.
Waltham, MassachusettsAges 18 years+ - NCT06021288Recruiting
Standard vs. lower dose dialysis for kidney failure in intensive care
This trial compares the usual dose of continuous dialysis with a lower dose to see if a lower dose is just as safe and effective for critically ill patients with sudden kidney failure.
MünsterAges 18 years+ - NCT06032884Recruiting
Comparing two dialysis methods for severe kidney injury in ICU
This trial compares two ways to filter blood (intermittent hemodialysis and continuous renal replacement therapy) for patients in the intensive care unit with severe acute kidney injury. It aims to find which method works better for critically ill patients.
BobignyAges 18 years+ - NCT06369064Recruiting
Comparing dialysis methods for kidney injury in the ICU
This trial compares two types of dialysis (hemodialysis and hemodiafiltration) to see which is better at removing waste from the blood in ICU patients with sudden kidney failure. It may help doctors choose the best treatment for you.
NîmesAges 18 years+ - NCT06397456Recruiting
Kidney education program for Black patients in the hospital
This study tests whether a special education and referral program helps Black patients with advanced kidney disease learn about their treatment options before they need dialysis or a transplant. If you join, you will get extra support while you're in the hospital.
Chicago, IllinoisAges 18–70 - NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT07643597Recruiting
Managing fluid removal in critically ill patients with acute kidney injury
This study looks at how to safely remove excess fluid from patients in the ICU who have sudden kidney failure and are on a special blood-filtering machine (CRRT). Researchers want to understand which patients have trouble tolerating fluid removal and how to prevent complications.
SalvadorAges 18 years+ - NCT06685367Recruiting
AI software for predicting acute kidney injury in ICU
This trial tests software that uses artificial intelligence to predict if a patient in the ICU might develop acute kidney injury (sudden kidney damage). It aims to see if the software is cost-effective and could help doctors catch problems earlier.
TaichungAges 20 years+ - NCT06835816Recruiting
Amino acid supplements during dialysis
This trial tests whether adding amino acid supplements during dialysis helps people with kidney failure. It may be an option if your doctor decides you need these supplements.
StockholmAges 18 years+ - NCT07230041Recruiting
Antibiotic removal during kidney therapy in the ICU
This trial studies how much certain antibiotics (meropenem, linezolid, and daptomycin) are removed when you're on a special blood-filtering machine called continuous renal replacement therapy (CRRT) for severe kidney injury. The results could help doctors give the right dose of antibiotics to treat infections effectively.
Milan, ItaliaAges 18 years+ - NCT03541785Enrolling by invitation
Using NGAL to guide fluids and start kidney-filtering in children
This study tests whether measuring a urine protein called NGAL can help doctors choose the right fluid amount and decide when to start a kidney-filtering treatment called CRRT in critically ill children with kidney injury. If it works, it may help treat kidney problems sooner and more safely.
Cincinnati, OhioAges 3 months–25 years - NCT06862180Recruiting
Meal replacement for diabetes control trial
This trial tests whether replacing one meal a day with a special shake can help people with type 2 diabetes improve their blood sugar control and overall health. If you have type 2 diabetes, take diabetes pills, and your blood sugar is not well controlled (HbA1c 7–10%), you may be able to join.
Kubang Kerian, KelantanAges 30–65 - NCT06005818RecruitingPhase 2
MRD-guided therapy for kidney cancer after surgery
This trial tests whether personalized monitoring of cancer DNA in your blood (MRD) can guide treatment decisions after kidney cancer surgery. If MRD is detected, you may receive extra immunotherapy to reduce the risk of cancer returning.
Birmingham, AlabamaAges 18 years+ - NCT06004336RecruitingPhase 2
Maintenance therapy after radiation for limited spread kidney cancer
This trial tests whether giving a maintenance medication (pembrolizumab) after targeted radiation helps keep kidney cancer that has spread to a few spots (5 or fewer) from growing. You would receive radiation to each spot and then be randomly assigned to receive either the medication or a placebo (inactive substance) for up to about 2 years.
Houston, TexasAges 18 years+ - NCT07270549RecruitingPhase 1/Phase 2
Gene therapy trial for children with CTNNB1 syndrome
This trial tests a one-time gene replacement therapy given into the fluid around the brain to help children with CTNNB1 neurodevelopmental syndrome. The goal is to see if replacing the faulty gene can improve development and reduce symptoms.
LjubljanaAges 2–12 - NCT07577570Recruiting
Calcium Treatment After Thyroid Surgery
This study tests whether calcium supplements help patients whose parathyroid glands aren't working properly after thyroid surgery. The parathyroid glands control calcium levels in your body, and they can be accidentally injured during thyroid removal.
Tallinn, OtherAges 18 years+ - NCT04146376Recruiting
Study of medicines for Von Willebrand disease during pregnancy
This study looks at how well a Von Willebrand disease treatment plan works during pregnancy, and whether some patients need extra “adjusting” of medicine. It may help prevent bleeding problems by matching treatment to each person’s lab results later in pregnancy.
Aurora, ColoradoAges 18 years+ - NCT04167033Recruiting
Checking heart rhythm timing in women with premature ovarian insufficiency
This study measures how quickly the heart “recharges” between beats (often shown as QT timing). It compares women with premature ovarian insufficiency to healthy women to understand whether ovarian insufficiency is linked to heart rhythm differences.
BordeauxAges 18–40 - NCT05855330RecruitingPhase 2
Arginine treatment for kids hospitalized with COVID-19
This Phase 2 trial tests whether replacing the body’s arginine (an amino acid) can improve outcomes for children and young adults hospitalized with COVID-19. It may help the immune response, but you must meet several safety criteria to join.
Atlanta, GeorgiaAges 3–21
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Common questions
- Are there clinical trials for renal replacement therapy?
- Yes. Clin2 currently lists 62 recruiting renal replacement therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a renal replacement therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a renal replacement therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.