Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05088694Enrolling by invitation
Test a classroom program to reduce extremism and intolerance
This trial evaluates a curriculum used in Bahraini middle and high schools that aims to reduce extremism and intolerance. It also gathers feedback from parents and D.A.R.E. officers who support the program to help improve it over time.
Greensboro, North CarolinaAges 11–18 - NCT05076682RecruitingPhase 2
Study for hard-to-treat triple-negative breast cancer that keeps growing
This Phase 2 trial tests a treatment plan for triple-negative breast cancer that has come back or kept progressing after prior immunotherapy (sometimes along with targeted therapy or chemotherapy). It may help by trying to make the cancer more controllable when it has become resistant to earlier treatment.
ShanghaiAges 18–70 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05049837Recruiting
Study lung cancer samples to understand relapse resistance
This trial looks at information and tissue from people with stage I to stage IIIA non-small cell lung cancer (NSCLC) who have surgery, sometimes with chemotherapy before surgery. Researchers want to understand why cancers come back (resistance) and how to better target treatments later.
Houston, TexasAges 18 years+ - NCT05046483Recruiting
Blood sugar study after a new heart attack
This study measures how your body handles sugar and related hormones in people after a new STEMI heart attack, and compares them with people who do not have diabetes or have prediabetes. The goal is to better understand metabolic changes after the event, which could help future care.
Düsseldorf, North Rhine-WestphaliaAges 18–80 - NCT05036707RecruitingPhase 1/Phase 2
Tick bite study in healthy adults
This study looks at how your body's immune system reacts to a tick bite. It may help doctors understand and prevent tick-borne diseases, which are illnesses spread by ticks, like Lyme disease.
Bethesda, MarylandAges 18–99 - NCT05000515Recruiting
Breathing muscle training to lower blood pressure in postmenopause
This study compares a breathing-based exercise program with regular aerobic exercise to help lower blood pressure and improve blood vessel function in postmenopausal women. It’s mainly for people with mildly elevated resting blood pressure who are not already doing very intense workouts.
Boulder, ColoradoAges 50 years+ - NCT04984226RecruitingPhase 2
Sodium bicarbonate for kidney disease energy and acidity
This trial studies whether taking sodium bicarbonate changes “energy” in cells and improves metabolic acidosis (an acid build-up) in people with moderate-to-severe chronic kidney disease. You may be able to join if your kidney function and blood bicarbonate levels fit their targets and you meet safety rules.
Sacramento, CaliforniaAges 21–85 - NCT04977791Recruiting
Study how drug resistance develops in lung cancer immunotherapy
This study looks at lung tumor tissue and blood to understand why immune checkpoint drugs can stop working in non-small cell lung cancer. It may help researchers find better ways to predict and overcome drug resistance.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04969315RecruitingPhase 1/Phase 2
Study of two new drugs for advanced kidney, prostate, lung, or mesothelioma cancer
This study tests two new study drugs (TT-4 and TT-10) alone and together in people with certain advanced cancers that have not responded to standard treatments. The goal is to see if these drugs are safe and effective in shrinking tumors or slowing the cancer's growth.
Los Angeles, CaliforniaAges 18 years+ - NCT04956016Recruiting
Compare two rTMS treatments for moderate to severe depression
This study tests whether a classic type of brain stimulation (rTMS) works better or the same as a deeper version for depression that keeps coming back or is ongoing. You may be offered one of the two stimulation options to see which helps reduce depressive symptoms.
PoitiersAges 18 years+ - NCT04946370RecruitingPhase 1/Phase 2
Pembrolizumab plus prostate cancer drug, with or without radiation
This early-phase trial tests pembrolizumab (an immune therapy) plus an androgen-receptor–blocking prostate cancer drug, and possibly a targeted radiation treatment. It’s for men with prostate cancer that has spread and keeps worsening despite standard hormone therapy, aiming to shrink tumors and improve control of the disease.
Boston, MassachusettsAges 18 years+ - NCT04943926Recruiting
Diet changes to help put type 2 diabetes into remission
This study tests whether specific dietary strategies can help people with type 2 diabetes reach remission (better blood sugar without ongoing high medication needs). You may be a good candidate if your diabetes is relatively recent, your weight is above a certain threshold, and your heart and other health conditions are stable.
Bergen, VestlandAges 24–70 - NCT04937751Recruiting
Tests for infection and resistance in invasive fusarium
This trial looks at lab test results from samples taken to check for a serious (invasive) fungal infection caused by fusarium. It may help improve how doctors identify the infection and its drug resistance, which can guide better treatment.
Vandœuvre-lès-NancyAges Any age - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT04923828Recruiting
Study drug resistance in very sick children with infections
This trial enrolls children in the pediatric intensive care unit (PICU) who have a severe infection. It aims to better understand germs and drug resistance so future treatments can be more effective.
Shanghai, Shanghai MunicipalityAges 1 month–16 years - NCT04921527RecruitingPhase 3
Chiauranib with weekly paclitaxel for tough ovarian cancer
This Phase 3 trial tests whether chiauranib combined with weekly paclitaxel can shrink recurrent ovarian, fallopian tube, or primary peritoneal cancer that did not respond to platinum chemotherapy. It is designed for people who have limited treatment options after platinum-resistant or platinum-refractory disease.
Shanghai, ChinaAges 18–70 - NCT04918186RecruitingPhase 2
Immunotherapy for platinum-resistant ovarian, with tumor testing
This Phase 2 study tests an immunotherapy approach for women whose high-grade serous ovarian cancer came back within 6 months of platinum chemotherapy. It may help shrink tumors and improve control of the disease, but you’ll need tumor biopsies and lab/heart/lung checks to join.
Chicago, IllinoisAges 18 years+ - NCT04887792RecruitingPhase 1/Phase 2
Acetazolamide for schizophrenia that hasn’t improved
This Phase 1/2 study tests whether acetazolamide can help people with treatment-resistant schizophrenia. It aims to see if adding this medication improves symptoms when standard antipsychotics haven’t worked enough.
Pittsburgh, PennsylvaniaAges 18–55 - NCT04886986RecruitingPhase 1
Testing a targeted radiation pill for advanced prostate cancer
This Phase 1 trial tests a small-molecule treatment that carries radioactive material to help treat prostate cancer that has spread and keeps growing despite standard hormone-blocking treatment. It’s mainly looking to find a safe dose and see how well the approach works in people with limited treatment options.
Brooklyn, New YorkAges 18–99 - NCT04846933Recruiting
Testing extra scans and data to guide ovarian cancer treatment
This trial collects information from people with suspected ovarian cancer and uses it to improve diagnosis and help predict which treatments may work. It may also look for targeted options, based on scan and medical data results.
TurkuAges 18 years+ - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT04798131Recruiting
Brain-scan training to reduce medication-resistant voices
This study uses brain scans (MRI) and real-time feedback to help train the brain to reduce frequent, distressing auditory hallucinations (hearing voices) in people with schizophrenia. If you qualify, you may try a structured neurofeedback program while researchers track changes in your symptoms.
LilleAges 18–60
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,186 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.