Clinical trials
Respiratory Distress Syndrome clinical trials
Below are recruiting respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 205 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06827184Recruiting
Best time for lying on stomach with severe lung failure
This trial is for people with severe lung failure (ARDS) who need a breathing machine. It tests how long lying on your stomach (prone position) helps improve breathing, by measuring changes in your body's oxygen levels and other vital signs.
TaipeiAges 18 years+ - NCT07030270Recruiting
Comparing surfactant delivery methods for preterm infants
This trial compares two ways to give surfactant (a substance that helps preterm babies' lungs work better) to preterm infants who need breathing support. It studies whether a small tube placed through the throat or a thin catheter works better for delivering the medication.
Dallas, TexasAges birth–3 days - NCT06083363Recruiting
Recovery after severe lung infection
This study follows patients who had severe pneumonia or acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU) to understand how they recover over time. It aims to identify factors that affect recovery trajectories.
Tortosa, TarragonaAges 18 years+ - NCT04966624Recruiting
Ultrasound-guided breathing strategy for new focal ARDS
This study tests a way to guide ventilator settings using lung ultrasound pictures in adults with very new, localized ("focal") ARDS. The goal is to see whether this approach improves care for people who just started needing a breathing machine.
DijonAges 18 years+ - NCT05609877Recruiting
Testing LISA breathing treatment for very preterm newborns
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
AalborgAges 6 months–7 months - NCT06212492Recruiting
Muscle relaxants and stomach positioning for ARDS
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
MarseilleAges 18 years+ - NCT06369584Recruiting
Prone Position for Children on ECMO with Severe ARDS
This trial tests if lying face-down (prone position) helps children with severe ARDS who are already on ECMO, a machine that supports the heart and lungs. It aims to see if this position improves recovery.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT05717218Recruiting
Testing special breathing monitoring during VV-ECMO in ARDS
This trial checks whether a special “breathing sensor belt” that watches breathing in real time can be used safely in adults with severe lung failure (ARDS) who are on a machine called VV-ECMO. It may help the care team better monitor ventilation while you’re critically ill.
ParisAges 18 years+ - NCT07669558Recruiting
Finding the best side-lying position for ARDS after abdominal surgery
This trial uses a special imaging test (electrical impedance tomography) to find the safest side position for patients with lung injury after abdominal surgery in the ICU. It aims to improve oxygen levels and breathing comfort.
ShanghaiAges 18 years+ - NCT07726940Recruiting
A Study of Immune Responses and ECMO in Severe Lung Injury
This study looks at how the immune system and ECMO (a machine that helps oxygenate blood) can improve outcomes for people with moderate to severe ARDS. If you join, researchers will monitor your condition and treatment to find better ways to manage this serious lung problem.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07726953Recruiting
Full-course ECMO for moderate-to-severe ARDS
This trial tests a full-course strategy using a heart-lung bypass machine (ECMO) for people with moderate-to-severe acute respiratory distress syndrome (ARDS), a serious lung condition. The goal is to see if starting and continuing ECMO throughout treatment improves recovery.
BeijingAges 18 years+ - NCT03825835Recruiting
Different oxygen levels at birth for very preterm babies
This trial studies whether giving 30% versus 60% oxygen during early resuscitation (breathing support) affects brain and nerve development in very low birthweight, very preterm infants. If you/your baby fits the birth and care timing requirements, the goal is to find an oxygen approach that supports better long-term outcomes.
Calgary, AlbertaAges birth–10 minutes - NCT04208126Recruiting
Early versus late ECMO start for severe lung failure
This trial compares starting ECMO early versus later in adults with severe lung failure (ARDS). It tests whether starting the life-support machine sooner can improve outcomes by the time doctors need it.
TübingenAges 18 years+ - NCT04221737Recruiting
Early breathing support for ARDS using a pressure release ventilator
This study looks at starting a specific type of breathing machine setting early in people with ARDS (a serious lung problem) to see if it improves outcomes. You might be able to take part if you are within 48 hours of needing a breathing tube and meet the lung oxygen criteria.
Guadalajara, JaliscoAges 18–80 - NCT04270045Recruiting
Breathing test in babies with bronchopulmonary dysplasia
This trial studies a breathing measurement test (forced oscillometry) in babies who were born early and have bronchopulmonary dysplasia (BPD), a long-term lung condition. It may help doctors better understand how babies’ lungs are working and guide future care.
Kansas City, MissouriAges Any age - NCT04460859Recruiting
Testing an electrical monitor in moderately severe lung failure
This trial tests a bedside breathing and lung-monitoring method that uses small electrodes on the chest. It is meant for people with moderate to severe ARDS (a serious lung inflammation problem) who are on a breathing machine, to help guide care.
São PauloAges 18 years+ - NCT04524091Recruiting
Predict breathing effort response to higher ventilator pressure
This trial looks at how much breathing effort changes when the ventilator uses a higher pressure in people who are recovering from ARDS. The goal is to predict who will respond better so care can be adjusted more safely and effectively.
San Martín, Buenos AiresAges 18 years+ - NCT04545424RecruitingPhase 2
Testing cooling treatment for severe lung failure in ICU patients
This trial tests whether therapeutic cooling (hypothermia) can improve outcomes in people with ARDS, a serious lung condition causing breathing failure. It may help by reducing harmful inflammation and lung injury, but eligibility is time-sensitive and requires ICU monitoring.
Los Angeles, CaliforniaAges 18–85 - NCT04754854Recruiting
Testing less blood recirculation during veno-venous ECMO
This trial studies whether a change in how a veno-venous ECMO machine works can reduce “blood recirculation” (blood returning to the circuit too quickly) in people with severe lung failure. It may help improve oxygen levels in adults whose ARDS is not responding to standard treatment.
BerlinAges 18 years+ - NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT05075161RecruitingPhase 3
Pirfenidone to help prevent lung scarring in ARDS
This Phase 3 trial tests whether pirfenidone can prevent or reduce lung scarring (fibrosis) in adults with ARDS who are within about a week of their illness starting. It may help by lowering harmful inflammation and the body’s scarring response.
Milan, MIAges 18 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05207852Recruiting
Dexamethasone study for preterm labor lung development
This trial studies how well dexamethasone works and how it behaves in the body when given during preterm labor to help the baby’s lungs mature. You may be able to join if you’re pregnant between 24–36 weeks and are receiving the study treatment per their schedule.
BeijingAges 20–40 - NCT05406570Recruiting
Personalized breathing settings for adults with severe ARDS
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
LyonAges 18 years+
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Common questions
- Are there clinical trials for respiratory distress syndrome?
- Yes. Clin2 currently lists 205 recruiting respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.