Clinical trials
Respiratory Distress Syndrome clinical trials
Below are recruiting respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05847634Recruiting
Testing how deep sedation affects blood flow in ARDS
This study looks at whether giving deep sedation (and sometimes muscle-paralyzing medicines) changes blood flow and oxygen delivery in the brain during acute respiratory distress syndrome (ARDS). It is a pilot study, meaning it mainly aims to understand safety and gather early information.
Winnipeg, ManitobaAges 18 years+ - NCT07570121RecruitingPhase 1
How Caffeine Moves Through Pregnancy and to the Baby
This study looks at how caffeine is absorbed and transferred to a baby during pregnancy in women at risk of early delivery. Researchers hope to understand safe caffeine use in this situation and potentially help prevent complications.
Indianapolis, IndianaAges 18 years+ - NCT06733168Recruiting
Electric imaging to guide breathing machine settings for ARDS
This trial tests whether using a special imaging technique (electrical impedance tomography) to set the breathing machine's pressure can improve oxygen levels and lung function in patients with moderate to severe ARDS, a serious lung condition.
HanoiAges 18 years+ - NCT06734988Recruiting
Esophageal Pressure Study for ARDS on Ventilators
This study looks at how well a special pressure measurement in your food pipe (esophageal pressure) works in people with severe lung injury (ARDS) who are on a breathing machine. It may help doctors improve ventilator settings for better lung recovery.
Sapporo, HokkaidoAges 16 years+ - NCT06254313Recruiting
Studying neutrophils in flu-related lung injury
This trial looks at how a type of white blood cell affects lung inflammation in people with severe influenza. It may help researchers find better treatments for respiratory failure caused by the flu or other infections.
BordeauxAges 18 years+ - NCT07542301Recruiting
Breathing Patterns in Premature Babies During Extubation
This study watches how premature babies breathe before and after removal of their breathing tube. By measuring breathing patterns, doctors hope to better understand when babies are ready to breathe on their own and improve outcomes.
Newark, DelawareAges birth–6 months - NCT04754854Recruiting
Testing less blood recirculation during veno-venous ECMO
This trial studies whether a change in how a veno-venous ECMO machine works can reduce “blood recirculation” (blood returning to the circuit too quickly) in people with severe lung failure. It may help improve oxygen levels in adults whose ARDS is not responding to standard treatment.
BerlinAges 18 years+ - NCT06696638Recruiting
Guiding breathing help with lung imaging vs. pressure in ARDS
This trial compares two ways to set the breathing machine for people with ARDS (a serious lung injury). One method uses a special imaging belt (EIT) to see how the lungs are working, while the other uses pressure measurements. The goal is to find the best way to adjust ventilator support to help you breathe more easily.
Wuhan, HubeiAges 18 years+ - NCT07514481Recruiting
Lung ultrasound comparison of two surfactant delivery methods in preterm babies
This study compares two ways of giving surfactant (a lung-coating medicine) to newborns with breathing trouble: LISA (a gentler, less invasive method) versus traditional breathing tube delivery. Researchers will use ultrasound to see how the medicine spreads in each baby's lungs to find the best approach.
DohaAges 6 months–10 months - NCT07511582RecruitingPhase 2
Steroids for severe breathing problems in the ICU
This study tests whether a corticosteroid (a type of anti-inflammatory medicine) can help people with severe breathing problems or serious infections who have a specific 'hyperinflammatory' pattern. If you are in the ICU on a ventilator, this trial may be an option for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07504731Recruiting
Effect of body position and breathing support on lung function
This study tests how changing a patient's body tilt and adjusting a ventilator's settings can help open up collapsed parts of the lungs. It may help patients with severe lung failure.
Nanjing, JiangsuAges 18 years+ - NCT06790875Recruiting
Comparing two ventilator settings for lung health in ARDS
This study tests two methods of adjusting a ventilator to see which one may better protect the lungs of patients with ARDS. It will help doctors learn how to set the machine to reduce strain on the lungs.
Wuhan, HubeiAges 18–80 - NCT07449572RecruitingPhase 1
Safety study of HT31-1 for healthy volunteers
This trial tests a new drug called HT31-1 to see if it's safe in healthy people. It looks at how the drug moves in your body and if it causes side effects. This is a first step before testing it in patients with ARDS (a serious lung condition).
Richmond, VirginiaAges 18–65 - NCT06805409Recruiting
Ultrasound test for kidney risk in ARDS patients
This study tests whether a special ultrasound of the veins (VExUS) can help predict kidney injury in people with severe breathing problems who are on a breathing machine and receiving medicine to support their blood pressure.
Créteil, Val de MarneAges 18–100 - NCT07439848RecruitingPhase 1/Phase 2
Stem cells for severe lung injury from sepsis
This trial tests if adding stem cells or their growth liquid to standard sepsis treatment helps adults with severe breathing problems. It may improve recovery for those whose family agrees to the study.
Jakarta Pusat, DKI JakartaAges 40 years+ - NCT07437391Recruiting
L-carnitine for preterm babies with breathing problems
This trial tests whether giving L-carnitine, a nutrient that helps cells make energy, to premature newborns with respiratory distress syndrome (RDS) can improve their health. It may help their bodies cope better in the NICU.
Muzaffargarh, Punjab ProvinceAges 1 hour–1 day - NCT06684119Recruiting
Testing best breathing tube pressure for children on a ventilator
This trial uses a special imaging tool (EIT) to find the best air pressure in the breathing tube for children on a ventilator. It aims to improve lung function in children with a lung condition called PARDS.
Los Angeles, CaliforniaAges birth–18 years - NCT05474196Recruiting
Monitoring pressures in the lungs for people with ARDS
This trial studies how pressure measurements from a special breathing and temperature monitoring system relate to fluid outside the lung blood vessels in people with ARDS. It may help doctors understand what those measurements mean and how to monitor patients more accurately.
Le Kremlin-BicêtreAges 18 years+ - NCT06123962Recruiting
Identifying lung injury subtypes to guide treatment
This study looks at different patterns in patients with a severe lung condition called ARDS, to better understand why some respond to treatments differently. You may help doctors learn how to personalize care.
BeijingAges 18 years+ - NCT05908227Recruiting
Testing nasal high-flow settings in stable preterm babies
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Mainz, Rhineland-PalatinateAges 5 months–7 months - NCT06586736Recruiting
Prone position study for ARDS patients
This trial studies how lying face down (prone position) affects breathing in patients with acute respiratory distress syndrome (ARDS). It may help doctors better monitor and treat patients on a breathing machine.
Chengdu, SichuanAges 18–90 - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05928052Recruiting
Spinal stimulation to help ARDS patients get off the ventilator
This study tests whether stimulating nerves in the spine can help people with severe lung injury (ARDS) breathe without a ventilator sooner. It may help shorten the time you need a breathing machine in the ICU.
Los Angeles, CaliforniaAges 18 years+ - NCT07309783Recruiting
Lung imaging to guide breathing support in ARDS
This trial uses a special lung imaging technique (EIT) to guide ventilator settings for people with ARDS. It may help improve breathing support and reduce lung injury.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for respiratory distress syndrome?
- Yes. Clin2 currently lists 200 recruiting respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.