Clinical trials
Respiratory Distress Syndrome clinical trials
Below are recruiting respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07313644Recruiting
Finding best breathing support for lung injury after trauma or surgery
This study tests a way to set breathing machine pressures using electrical imaging of the lungs. It aims to find the best settings for patients with lung injury after trauma or major surgery, helping them breathe better with less damage.
HanoiAges 18–90 - NCT07284888Recruiting
Prone positioning for ARDS patients on ventilators
This study looks at how placing patients on their stomach (prone positioning) affects those with serious lung failure (ARDS) who are on a breathing machine. It aims to learn more about the best practices for this treatment in the ICU.
Nanjing, JiangsuAges 18 years+ - NCT07269743Recruiting
Aerosol therapy for ARDS patients on ventilators
This trial tests whether delivering medication through a ventilator mask (aerosol therapy) can help adults with ARDS breathe better. It is designed for patients who are already on a breathing machine.
Lucknow, Uttar PradeshAges 18 years+ - NCT07262541Recruiting
Measuring airway opening pressure in children on ventilators
This study tests a simple way to measure the pressure needed to open the airways in children on a breathing machine. It may help doctors provide better breathing support for your child in the intensive care unit.
ParisAges Up to 17 years - NCT07265583Recruiting
Predicting lung injury in premature babies
This study looks at premature babies to see if we can predict lung injury early. It may help doctors provide better care for babies born early or with low birth weight.
PaviaAges 6 months–7 months - NCT05960929RecruitingPhase 3
Breathing support for premature babies with lung distress
This Phase 3 trial tests whether InfasurfAero™ (a type of surfactant given as aerosol) works better than a sham treatment in preterm babies with respiratory distress syndrome (RDS). It aims to improve breathing in the first hours of life for babies who need CPAP.
Phoenix, ArizonaAges 7 months–8 months - NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT07248995Recruiting
Ultrasound to set breathing support in brain injury patients with lung issues
This trial tests if chest and head ultrasound can help doctors adjust the breathing machine (PEEP) for patients with both a severe brain injury and a serious lung condition called ARDS. The goal is to improve care without harming the brain.
ThessalonikiAges 18 years+ - NCT07235345Enrolling by invitation
Lung medication with different oxygen levels for premature babies
This study tests a lung medication called pulmonary surfactant, given with different oxygen levels, to help very premature babies (born before 32 weeks) who have breathing difficulties. The goal is to see which oxygen level works best with non-invasive breathing support.
Henan, ZhengzhouAges 6 months–7 months - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT06911450Recruiting
Ultrasound test for lung strain in ICU patients
This study uses a special ultrasound technique to measure how the lungs stretch (pleural strain) during breathing. It aims to see if this measurement works in ICU patients, both those breathing on their own and those on a ventilator, and how it relates to the pressure needed to inflate the lungs.
Wuhu, AnhuiAges 18–75 - NCT07211529Recruiting
Nerve block during chest surgery to reduce complications
This trial tests whether a numbing injection near the spine (paravertebral block) given during keyhole chest surgery can lower the risk of problems after surgery. It might help patients recover more comfortably.
Wuhan, HubeiAges 18–80 - NCT07193771Recruiting
Altitude and Outcomes in Children with ARDS
This study looks at how elevation (altitude) affects the recovery of children with a serious lung condition called ARDS who are on a breathing machine in the intensive care unit.
Sucre, Chuquisaca DepartmentAges 1 month–18 years - NCT07176117Enrolling by invitation
Surfactant via airway device for breathing trouble in newborns
This trial tests if giving surfactant (a natural substance that helps lungs stay open) through a special airway device can help late preterm and early term infants with breathing problems. The goal is to see if this approach works better than current methods without needing a breathing tube.
Chula Vista, CaliforniaAges 8 months–9 months - NCT07126964Recruiting
Extended prone positioning for ARDS patients on ventilators
This trial tests if longer periods of lying face-down (prone positioning) can help people with ARDS who are on a breathing machine. It aims to improve oxygen levels and possibly reduce the need for more invasive treatments.
ParisAges 18 years+ - NCT07125079Recruiting
Studying immune cells and a new treatment for ARDS
This study looks at how the immune system responds in people with ARDS (a severe lung injury) and tests a new treatment called PIP-2 in the lab to see if it might help. It aims to better understand lung injury and find new ways to treat it.
Philadelphia, PennsylvaniaAges 21–90 - NCT06946914RecruitingPhase 4
Misoprostol before planned c-section
This trial tests if giving misoprostol before a planned c-section can help reduce bleeding. It might make the surgery safer for women who meet certain criteria.
Kafr Ash Shaykh, EgyptAges 20–35 - NCT06967207Recruiting
Electrical imaging lung monitor for ARDS outcomes
This study tests if a special imaging technique (Electrical Impedance Tomography or EIT) can help doctors better predict outcomes in people with severe lung injury (ARDS). The goal is to use regular, safe lung scans to guide breathing treatment.
Guangzhou, GuangdongAges 18–80 - NCT07098910Recruiting
Surfactant therapy for premature babies with breathing problems
This trial tests whether giving surfactant (a substance that helps lungs stay open) to premature babies with Respiratory Distress Syndrome (RDS) through a mask on the throat (supraglottic airway) is safe and effective. It may be an option for babies who need extra oxygen but are not on a breathing tube.
HanoiAges Up to 2 days - NCT05717218Recruiting
Testing special breathing monitoring during VV-ECMO in ARDS
This trial checks whether a special “breathing sensor belt” that watches breathing in real time can be used safely in adults with severe lung failure (ARDS) who are on a machine called VV-ECMO. It may help the care team better monitor ventilation while you’re critically ill.
ParisAges 18 years+ - NCT04460859Recruiting
Testing an electrical monitor in moderately severe lung failure
This trial tests a bedside breathing and lung-monitoring method that uses small electrodes on the chest. It is meant for people with moderate to severe ARDS (a serious lung inflammation problem) who are on a breathing machine, to help guide care.
São PauloAges 18 years+ - NCT04208126Recruiting
Early versus late ECMO start for severe lung failure
This trial compares starting ECMO early versus later in adults with severe lung failure (ARDS). It tests whether starting the life-support machine sooner can improve outcomes by the time doctors need it.
TübingenAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07025421Recruiting
Using vertical positioning for ARDS patients
This study tests whether raising the head of the bed (vertical positioning) can help patients with ARDS breathe better. It may offer a simple, non-drug way to improve oxygen levels.
Birmingham, AlabamaAges 18–80
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Common questions
- Are there clinical trials for respiratory distress syndrome?
- Yes. Clin2 currently lists 200 recruiting respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.