Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05354141RecruitingPhase 3
Tested treatment with tiny lung particles for moderate to severe ARDS
This Phase 3 trial studies an “extracellular vesicle” treatment in people with moderate to severe ARDS, a serious lung breathing problem. The goal is to see whether the treatment can improve outcomes compared with standard care.
Phoenix, ArizonaAges 18–75 - NCT07603310Recruiting
PEEP levels in ARDS based on lung response
This study tests whether adjusting ventilator settings based on how well your lungs respond can improve oxygen and reduce damage in patients with moderate to severe ARDS, within the first 36 hours of diagnosis.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT07090460Recruiting
Measuring lung overstretch in prone-position ARDS patients
This study uses a special imaging belt (EIT) to check if the lungs are being overstretched when patients with severe breathing problems are placed on their stomach (prone position). It may help doctors adjust breathing machines more safely.
Bayonne, Centre Hospitalier de La Côte BasqueAges 18 years+ - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Newport Beach, CaliforniaAges 18 years+ - NCT07289711Recruiting
Study of ARDS subtypes for targeted treatment
This study looks at different types of inflammation in patients with Acute Respiratory Distress Syndrome (ARDS), a serious lung condition. It aims to find which treatments work best for each subtype.
Nanjing, JiangsuAges 18 years+ - NCT06874478Recruiting
Breathing help for babies born by planned C-section
This study looks at whether giving steroids before a planned C-section at full term can help babies breathe better after birth. It may be an option for pregnant women who are scheduled for a C-section and meet certain health criteria.
AsyutAges 20–39 - NCT07154134Recruiting
Blood markers in preterm babies with breathing problems
This study looks at two substances in the blood (endocan and copeptin) to see if they can help doctors understand breathing problems in premature babies. It may lead to better ways to care for these infants.
Tanta, El-GharbiaAges 6 months–8 months - NCT06357780Recruiting
Comparing two breath-timing methods for breathing masks in adults
This study compares two ways of timing a breathing mask's support to match your own breaths. If you're in the ICU or ER and need help breathing for at least 2 more hours, this trial may test which method works better.
IzmirAges 18 years+ - NCT05002478Recruiting
Prone positioning for very sick babies with lung distress
This trial tests whether turning very sick, ventilated infants onto their stomach (prone positioning) can improve breathing when they have severe lung distress from likely pneumonia or bronchiolitis. It may help your baby get better oxygen levels and recover faster, while doctors closely monitor safety.
ViennaAges Up to 1 year - NCT03736707Recruiting
Testing two breathing machines in very preterm babies
This study compares two ways of helping very preterm infants breathe: a special high-frequency ventilation method versus the standard mechanical ventilator. It aims to see which method works better for preterm babies with breathing failure soon after birth.
Chongqing, Chongqing MunicipalityAges 1 minute–1 hour - NCT04472260Recruiting
Testing safe early standing for adults with severe lung failure
This trial checks whether it’s safe and doable to help people with acute respiratory distress syndrome (ARDS) start standing early, while they are closely monitored. It may help some patients begin upright movement sooner, with the goal of improving safety.
OrléansAges 18 years+ - NCT07558538RecruitingEarly Phase 1
Inhaled Growth Factor Treatment for Severe Lung Failure
This early-stage trial tests whether an inhaled medication called recombinant human keratinocyte growth factor-2 (rh-KGF-2) can help patients with acute respiratory distress syndrome (ARDS)—a serious condition where the lungs cannot deliver enough oxygen to the blood. The drug is designed to help repair lung tissue damage.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07086755RecruitingPhase 2/Phase 3
Vadadustat treatment for lung injury from infection
This trial tests a pill called vadadustat for people with a serious lung condition called ARDS, which makes it hard to breathe. The drug may reduce inflammation and improve oxygen levels, helping patients recover without needing a breathing tube.
Houston, TexasAges 18 years+ - NCT07202299Recruiting
Weaning preterm babies off high-frequency breathing machines
This trial tests two different ways to safely take preterm babies off a special breathing machine (HFOV). It aims to find which method works better for babies with breathing problems (respiratory distress syndrome).
Al MansurahAges Any age - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT06650137Recruiting
Using Diaphragm Ultrasound to Find the Cause of Breathing Trouble
This study tests if ultrasound of your diaphragm (the muscle that helps you breathe) can help doctors find the cause of sudden breathing trouble. It may help patients who come to the emergency room with fast or difficult breathing and low oxygen levels.
Nîmes, GardAges 18 years+ - NCT04220463Recruiting
Hypnosis during noninvasive breathing support for ICU lung illness
This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.
Rennes, Brittany RegionAges 18 years+ - NCT07281300Recruiting
Mindfulness for breathing distress in lung cancer
This trial tests a mindfulness-based program to help lung cancer patients manage breathing difficulty and other symptoms. It aims to reduce distress and improve daily life.
Hong KongAges 18 years+ - NCT04626154Recruiting
Testing a device for breathing problems during chest movement
This study looks at how well a special device can be used in children to understand breathing problems related to chest and belly movement. It may help researchers improve care for kids who have breathing distress.
Boston, MassachusettsAges 4 weeks–17 years - NCT07686315Recruiting
Safer breathing with advanced monitoring on a ventilator
This trial is testing a new way to monitor your breathing while you are on a ventilator, to make it safer. It is for people who need a ventilator for reasons other than lung failure, like after a coma, injury, or severe infection.
Milan, LombardyAges 18 years+ - NCT05164744Recruiting
MRI study of heart tissue changes after COVID-19
This study uses a heart MRI to look for leftover (healing) changes in heart tissue after COVID-19. It may help researchers better understand what ongoing heart effects can happen after infection.
Brooklyn, New YorkAges 18 years+ - NCT06026163RecruitingPhase 2/Phase 3
Caffeine for breathing help in late preterm babies
This trial tests if giving caffeine to late preterm babies with breathing problems helps them need less breathing support. It could be an extra treatment alongside standard care.
Madinah, Medina RegionAges 1 day–3 days - NCT07083973Recruiting
Monitoring lung function with 3D imaging in ARDS
This study is testing a new way to monitor lung function using a 3D electrical imaging device (EIT) while patients with ARDS lie on their stomach to improve breathing. The goal is to see if this imaging helps doctors better understand how the lungs are working.
Beijing, Beijing MunicipalityAges 18 years+
Hear when a new Respiratory Distress trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 220 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.