Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT06007547RecruitingPhase 4
Preventive surfactant therapy for preterm babies
This trial tests whether giving surfactant (a foam that helps lungs stay open) before breathing problems start can help very premature babies (born before 30 weeks) breathe better. It might reduce the need for a breathing tube.
Evanston, IllinoisAges Up to 15 minutes - NCT06037330RecruitingPhase 4
Study of nalbuphine for ARDS after surgery
This trial tests if the drug nalbuphine can help patients with acute respiratory distress syndrome (ARDS) after surgery. It aims to see if it improves breathing and pain while staying in the ICU.
Jinan, ShandongAges 18 years+ - NCT06052436RecruitingPhase 1/Phase 2
Treg cell therapy for COVID-19 and acute respiratory distress
This trial tests a new cell therapy using Treg cells from thymic tissue to calm an overactive immune response in severe COVID-19 and ARDS. It aims to improve breathing and reduce inflammation.
Madrid, MadridAges 18–65 - NCT06062212Recruiting
Effects of lung pressure on recovery in severe ARDS on ECMO
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT06074380RecruitingPhase 4
Surfactant therapy comparison for preterm infants
This trial compares a new method of giving surfactant (a substance that helps babies' lungs work better) to preterm infants who have breathing problems. The goal is to see if giving surfactant through a thin tube without a breathing tube works as well as the usual method.
Evanston, IllinoisAges Up to 2 days - NCT06123962Recruiting
Identifying lung injury subtypes to guide treatment
This study looks at different patterns in patients with a severe lung condition called ARDS, to better understand why some respond to treatments differently. You may help doctors learn how to personalize care.
BeijingAges 18 years+ - NCT06148467Recruiting
Understanding breathing patterns and adjusting ventilator support
This study looks at a specific breathing pattern called reverse triggering in people with ARDS (a serious lung condition) who are on a ventilator. The goal is to see how adjusting the ventilator settings affects this pattern and improves breathing coordination.
GuadalajaraAges 18–90 - NCT06254313Recruiting
Studying neutrophils in flu-related lung injury
This trial looks at how a type of white blood cell affects lung inflammation in people with severe influenza. It may help researchers find better treatments for respiratory failure caused by the flu or other infections.
BordeauxAges 18 years+ - NCT06280872Recruiting
Cord clamping study for moderate and late preterm babies
This trial studies a different way of clamping the umbilical cord after birth to see if it helps moderately preterm babies (born between 32 and 37 weeks). It may improve their health right after delivery.
BrusselsAges 7 months–8 months - NCT06295484Recruiting
Comparing two breathing support methods for very small babies
This study compares two types of breathing support (nasal CPAP and NIPPV) for very low birth weight preterm infants to see which one works better. The goal is to find the best way to help these babies breathe more easily.
Toronto, OntarioAges 1 day–8 months - NCT06430554Recruiting
Personalized ventilation for ARDS patients on breathing machines
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Nanjing, JiangsuAges 18–85 - NCT06990477Recruiting
EIT-guided breathing machine settings for ARDS
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
Hefei, AnhuiAges 19–90 - NCT07633366Recruiting
Understanding ARDS Through Lung Fluid and Imaging Analysis
This study examines lung fluid samples and imaging scans from patients on breathing machines to better understand acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers hope this will help doctors diagnose and treat ARDS more effectively in the future.
Vienna, State of ViennaAges 18 years+ - NCT06387823Recruiting
Testing Sivelestat Sodium and Dexamethasone for Severe ARDS
This trial tests a combination of two medicines (Sivelestat Sodium and Dexamethasone) to see if they can help people with severe lung injury (ARDS) who need a breathing machine. It is for patients whose condition has just worsened and who are on a ventilator early in their illness.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06477861Recruiting
Elastic power predicts ARDS severity and death risk
This study looks at a new way to predict how serious ARDS (a severe lung injury from pneumonia) is and the chance of death. Doctors will measure something called "elastic power" to see if it helps guide treatment for patients on a breathing machine.
Banhā, Al QalubeyahAges 18–65 - NCT07309783Recruiting
Lung imaging to guide breathing support in ARDS
This trial uses a special lung imaging technique (EIT) to guide ventilator settings for people with ARDS. It may help improve breathing support and reduce lung injury.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06880016Recruiting
Lung ultrasound after surfactant in preterm babies
This study uses lung ultrasound to see how different ways of giving surfactant (a medicine for breathing problems) affect preterm babies born before 32 weeks. It may help doctors choose the best method for your baby.
Konya, KaratayAges 1 day–5 days - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06550219Recruiting
Using a face mask breathing support in premature babies with breathing trouble
This study tests whether delivering breathing support through a soft face mask (nasal non-invasive ventilation) can help premature babies who are having trouble breathing. Doctors will also use ultrasound to monitor their lungs.
AlexandriaAges 1 hour–1 day - NCT06557551Recruiting
Surfactant for preterm babies born before 28 weeks
This trial tests giving surfactant through a thin tube into the windpipe right after birth for babies born before 28 weeks. It aims to help their lungs work better and reduce breathing problems.
Dublin, None SelectedAges Up to 30 minutes - NCT06586736Recruiting
Prone position study for ARDS patients
This trial studies how lying face down (prone position) affects breathing in patients with acute respiratory distress syndrome (ARDS). It may help doctors better monitor and treat patients on a breathing machine.
Chengdu, SichuanAges 18–90 - NCT06594458Recruiting
New method to keep mom and baby together after C-section
This study tests a new procedure to reduce separation between mother and newborn after a planned C-section. It may help babies with mild breathing problems who need a little extra oxygen stay with their moms instead of going to a separate nursery.
RomaAges 1 minute–3 days - NCT06622902Recruiting
How flow changes affect CO2 in preemies on high-flow breathing support
This study watches how changing the flow of air through a breathing device (high-flow nasal cannula) affects carbon dioxide levels in preemies. It helps doctors learn the safest way to adjust breathing support for fragile infants.
HaifaAges Any age
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Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 220 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.