Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06550219Recruiting
Using a face mask breathing support in premature babies with breathing trouble
This study tests whether delivering breathing support through a soft face mask (nasal non-invasive ventilation) can help premature babies who are having trouble breathing. Doctors will also use ultrasound to monitor their lungs.
AlexandriaAges 1 hour–1 day - NCT07439848RecruitingPhase 1/Phase 2
Stem cells for severe lung injury from sepsis
This trial tests if adding stem cells or their growth liquid to standard sepsis treatment helps adults with severe breathing problems. It may improve recovery for those whose family agrees to the study.
Jakarta Pusat, DKI JakartaAges 40 years+ - NCT07437391Recruiting
L-carnitine for preterm babies with breathing problems
This trial tests whether giving L-carnitine, a nutrient that helps cells make energy, to premature newborns with respiratory distress syndrome (RDS) can improve their health. It may help their bodies cope better in the NICU.
Muzaffargarh, Punjab ProvinceAges 1 hour–1 day - NCT07426016Recruiting
Comparing two ways to give surfactant to premature babies
This study compares two methods—video laryngoscopy and direct laryngoscopy—to give surfactant (a medicine that helps babies' lungs work better) to very premature infants. It aims to find which method is safer and easier for babies born at 28 weeks or earlier who need surfactant within the first 36 hours after birth.
Dallas, TexasAges birth–3 days - NCT06684119Recruiting
Testing best breathing tube pressure for children on a ventilator
This trial uses a special imaging tool (EIT) to find the best air pressure in the breathing tube for children on a ventilator. It aims to improve lung function in children with a lung condition called PARDS.
Los Angeles, CaliforniaAges birth–18 years - NCT05474196Recruiting
Monitoring pressures in the lungs for people with ARDS
This trial studies how pressure measurements from a special breathing and temperature monitoring system relate to fluid outside the lung blood vessels in people with ARDS. It may help doctors understand what those measurements mean and how to monitor patients more accurately.
Le Kremlin-BicêtreAges 18 years+ - NCT06123962Recruiting
Identifying lung injury subtypes to guide treatment
This study looks at different patterns in patients with a severe lung condition called ARDS, to better understand why some respond to treatments differently. You may help doctors learn how to personalize care.
BeijingAges 18 years+ - NCT05908227Recruiting
Testing nasal high-flow settings in stable preterm babies
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Mainz, Rhineland-PalatinateAges 5 months–7 months - NCT06586736Recruiting
Prone position study for ARDS patients
This trial studies how lying face down (prone position) affects breathing in patients with acute respiratory distress syndrome (ARDS). It may help doctors better monitor and treat patients on a breathing machine.
Chengdu, SichuanAges 18–90 - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05928052Recruiting
Spinal stimulation to help ARDS patients get off the ventilator
This study tests whether stimulating nerves in the spine can help people with severe lung injury (ARDS) breathe without a ventilator sooner. It may help shorten the time you need a breathing machine in the ICU.
Los Angeles, CaliforniaAges 18 years+ - NCT07309783Recruiting
Lung imaging to guide breathing support in ARDS
This trial uses a special lung imaging technique (EIT) to guide ventilator settings for people with ARDS. It may help improve breathing support and reduce lung injury.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04484727Recruiting
Measure lung pressure and breathing in ventilated ICU patients
This study measures lung pressures and breathing mechanics during planned or emergency breathing machine (ventilator) treatment. It may help doctors better understand lung behavior in both healthy and breathing-distressed lungs to improve care.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT07284888Recruiting
Prone positioning for ARDS patients on ventilators
This study looks at how placing patients on their stomach (prone positioning) affects those with serious lung failure (ARDS) who are on a breathing machine. It aims to learn more about the best practices for this treatment in the ICU.
Nanjing, JiangsuAges 18 years+ - NCT07269743Recruiting
Aerosol therapy for ARDS patients on ventilators
This trial tests whether delivering medication through a ventilator mask (aerosol therapy) can help adults with ARDS breathe better. It is designed for patients who are already on a breathing machine.
Lucknow, Uttar PradeshAges 18 years+ - NCT07265583Recruiting
Predicting lung injury in premature babies
This study looks at premature babies to see if we can predict lung injury early. It may help doctors provide better care for babies born early or with low birth weight.
PaviaAges 6 months–7 months - NCT07262541Recruiting
Measuring airway opening pressure in children on ventilators
This study tests a simple way to measure the pressure needed to open the airways in children on a breathing machine. It may help doctors provide better breathing support for your child in the intensive care unit.
ParisAges Up to 17 years - NCT07261787RecruitingPhase 4
Surfactant given in 1 vs. 5 minutes for very preterm babies
This trial compares giving a breathing treatment (surfactant) over 1 minute versus 5 minutes to help very premature babies born before 28 weeks. The goal is to see which timing helps the baby's breathing and heart rate stabilize better.
GrazAges birth–3 days - NCT05960929RecruitingPhase 3
Breathing support for premature babies with lung distress
This Phase 3 trial tests whether InfasurfAero™ (a type of surfactant given as aerosol) works better than a sham treatment in preterm babies with respiratory distress syndrome (RDS). It aims to improve breathing in the first hours of life for babies who need CPAP.
Phoenix, ArizonaAges 7 months–8 months - NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT07248995Recruiting
Ultrasound to set breathing support in brain injury patients with lung issues
This trial tests if chest and head ultrasound can help doctors adjust the breathing machine (PEEP) for patients with both a severe brain injury and a serious lung condition called ARDS. The goal is to improve care without harming the brain.
ThessalonikiAges 18 years+ - NCT07243054Recruiting
How IV fluids before birth affect newborn weight loss
This trial looks at whether giving IV fluids to mothers before delivery affects how much weight healthy, full-term newborns lose in their first days of life. It is for mothers who feed their baby only formula in the hospital.
Amiens, PicardieAges 18 years+ - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT07235345Enrolling by invitation
Lung medication with different oxygen levels for premature babies
This study tests a lung medication called pulmonary surfactant, given with different oxygen levels, to help very premature babies (born before 32 weeks) who have breathing difficulties. The goal is to see which oxygen level works best with non-invasive breathing support.
Henan, ZhengzhouAges 6 months–7 months
Hear when a new Respiratory Distress trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 216 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.