Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05816954Recruiting
Imaging test to predict lung injury risk in ARDS
This study looks at scan images to better predict the risk of a serious lung complication (barotrauma) in people with ARDS. It may help doctors choose safer treatment strategies in the ICU.
Catanzaro, CalabriaAges 18 years+ - NCT06074380RecruitingPhase 4
Surfactant therapy comparison for preterm infants
This trial compares a new method of giving surfactant (a substance that helps babies' lungs work better) to preterm infants who have breathing problems. The goal is to see if giving surfactant through a thin tube without a breathing tube works as well as the usual method.
Evanston, IllinoisAges Up to 2 days - NCT06007547RecruitingPhase 4
Preventive surfactant therapy for preterm babies
This trial tests whether giving surfactant (a foam that helps lungs stay open) before breathing problems start can help very premature babies (born before 30 weeks) breathe better. It might reduce the need for a breathing tube.
Evanston, IllinoisAges Up to 15 minutes - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT06622902Recruiting
How flow changes affect CO2 in preemies on high-flow breathing support
This study watches how changing the flow of air through a breathing device (high-flow nasal cannula) affects carbon dioxide levels in preemies. It helps doctors learn the safest way to adjust breathing support for fragile infants.
HaifaAges Any age - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT06430554Recruiting
Personalized ventilation for ARDS patients on breathing machines
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Nanjing, JiangsuAges 18–85 - NCT06421506Recruiting
Giving surfactant through a thin tube in late preterm babies
This trial tests a less invasive way to give surfactant (a lung treatment) to babies born a few weeks early who need breathing help. It aims to see if this method works as well as standard care.
LondonAges 8 months–9 months - NCT06148467Recruiting
Understanding breathing patterns and adjusting ventilator support
This study looks at a specific breathing pattern called reverse triggering in people with ARDS (a serious lung condition) who are on a ventilator. The goal is to see how adjusting the ventilator settings affects this pattern and improves breathing coordination.
GuadalajaraAges 18–90 - NCT06052436RecruitingPhase 1/Phase 2
Treg cell therapy for COVID-19 and acute respiratory distress
This trial tests a new cell therapy using Treg cells from thymic tissue to calm an overactive immune response in severe COVID-19 and ARDS. It aims to improve breathing and reduce inflammation.
Madrid, MadridAges 18–65 - NCT05925075Enrolling by invitation
Lung ultrasound check for breathing problems in very premature babies
This trial tests whether doing a bedside lung ultrasound can help doctors assess and manage breathing problems in very premature infants. It may help guide care decisions for infants who are struggling to breathe, especially those needing breathing support.
Phoenix, ArizonaAges birth+ - NCT04966624Recruiting
Ultrasound-guided breathing strategy for new focal ARDS
This study tests a way to guide ventilator settings using lung ultrasound pictures in adults with very new, localized ("focal") ARDS. The goal is to see whether this approach improves care for people who just started needing a breathing machine.
DijonAges 18 years+ - NCT05855317Recruiting
Tests blood marker link to lung blood clots in ARDS
This study looks at a blood marker (EV-TF) to see whether it helps predict pulmonary embolism—blood clots in the lungs—in people with ARDS who are in the ICU. Results may help doctors better identify who is at higher risk.
MarseilleAges 18 years+ - NCT05801224Recruiting
Inhaled nitric oxide for lung injury in intensive care
This study tests whether giving inhaled nitric oxide gas helps improve lung function in patients on a breathing tube with mild to moderate acute lung injury (ARDS). Participants will receive standard care plus the study gas, and the team will use special imaging to see how the lungs respond.
Boston, MassachusettsAges 18–80 - NCT05767671Recruiting
Breathing tube patients in ICU tested for lung inflammation treatment
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Denver, ColoradoAges 18–99 - NCT05604430Enrolling by invitation
Study of pre-hospital breathing support with a specific ventilator
This study looks at breathing support given outside the hospital using a particular ZOLL ventilator model and software version. If you were treated with the right equipment, the team will use the ventilator’s recorded data to evaluate how ventilation was delivered.
Hartford, ConnecticutAges Any age - NCT05075161RecruitingPhase 3
Pirfenidone to help prevent lung scarring in ARDS
This Phase 3 trial tests whether pirfenidone can prevent or reduce lung scarring (fibrosis) in adults with ARDS who are within about a week of their illness starting. It may help by lowering harmful inflammation and the body’s scarring response.
Milan, MIAges 18 years+ - NCT04524091Recruiting
Predict breathing effort response to higher ventilator pressure
This trial looks at how much breathing effort changes when the ventilator uses a higher pressure in people who are recovering from ARDS. The goal is to predict who will respond better so care can be adjusted more safely and effectively.
San Martín, Buenos AiresAges 18 years+ - NCT04369599Enrolling by invitation
Test chest vibration during ventilation for severe lung failure
This study looks at whether a special chest “vest” and related lung measurements can improve breathing in people with sudden severe lung failure who need a breathing machine. You may be eligible if you have ARDS and can safely use the vest during mechanical ventilation.
Atlanta, GeorgiaAges 18 years+ - NCT04270045Recruiting
Breathing test in babies with bronchopulmonary dysplasia
This trial studies a breathing measurement test (forced oscillometry) in babies who were born early and have bronchopulmonary dysplasia (BPD), a long-term lung condition. It may help doctors better understand how babies’ lungs are working and guide future care.
Kansas City, MissouriAges Any age - NCT04221737Recruiting
Early breathing support for ARDS using a pressure release ventilator
This study looks at starting a specific type of breathing machine setting early in people with ARDS (a serious lung problem) to see if it improves outcomes. You might be able to take part if you are within 48 hours of needing a breathing tube and meet the lung oxygen criteria.
Guadalajara, JaliscoAges 18–80 - NCT06733168Recruiting
Electric imaging to guide breathing machine settings for ARDS
This trial tests whether using a special imaging technique (electrical impedance tomography) to set the breathing machine's pressure can improve oxygen levels and lung function in patients with moderate to severe ARDS, a serious lung condition.
HanoiAges 18 years+ - NCT07313644Recruiting
Finding best breathing support for lung injury after trauma or surgery
This study tests a way to set breathing machine pressures using electrical imaging of the lungs. It aims to find the best settings for patients with lung injury after trauma or major surgery, helping them breathe better with less damage.
HanoiAges 18–90
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Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 216 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.