Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 220 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04524091Recruiting
Predict breathing effort response to higher ventilator pressure
This trial looks at how much breathing effort changes when the ventilator uses a higher pressure in people who are recovering from ARDS. The goal is to predict who will respond better so care can be adjusted more safely and effectively.
San Martín, Buenos AiresAges 18 years+ - NCT04545424RecruitingPhase 2
Testing cooling treatment for severe lung failure in ICU patients
This trial tests whether therapeutic cooling (hypothermia) can improve outcomes in people with ARDS, a serious lung condition causing breathing failure. It may help by reducing harmful inflammation and lung injury, but eligibility is time-sensitive and requires ICU monitoring.
Los Angeles, CaliforniaAges 18–85 - NCT04754854Recruiting
Testing less blood recirculation during veno-venous ECMO
This trial studies whether a change in how a veno-venous ECMO machine works can reduce “blood recirculation” (blood returning to the circuit too quickly) in people with severe lung failure. It may help improve oxygen levels in adults whose ARDS is not responding to standard treatment.
BerlinAges 18 years+ - NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT07699666Recruiting
Cord clamping timing for preterm babies
This study compares waiting a bit before clamping the umbilical cord versus clamping it right away for babies born between 32 and 37 weeks of pregnancy. It helps determine which approach may be better for preterm infants.
Tunis, Tunis GovernorateAges birth+ - NCT05075161RecruitingPhase 3
Pirfenidone to help prevent lung scarring in ARDS
This Phase 3 trial tests whether pirfenidone can prevent or reduce lung scarring (fibrosis) in adults with ARDS who are within about a week of their illness starting. It may help by lowering harmful inflammation and the body’s scarring response.
Milan, MIAges 18 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05207852Recruiting
Dexamethasone study for preterm labor lung development
This trial studies how well dexamethasone works and how it behaves in the body when given during preterm labor to help the baby’s lungs mature. You may be able to join if you’re pregnant between 24–36 weeks and are receiving the study treatment per their schedule.
BeijingAges 20–40 - NCT05406570Recruiting
Personalized breathing settings for adults with severe ARDS
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
LyonAges 18 years+ - NCT05474196Recruiting
Monitoring pressures in the lungs for people with ARDS
This trial studies how pressure measurements from a special breathing and temperature monitoring system relate to fluid outside the lung blood vessels in people with ARDS. It may help doctors understand what those measurements mean and how to monitor patients more accurately.
Le Kremlin-BicêtreAges 18 years+ - NCT05492344Recruiting
Ultrasound-guided breathing support for severe lung failure
This study tests whether using an ultrasound scan to guide a breathing machine settings can improve care for people with moderate or severe ARDS, a serious lung condition. If you qualify, the team will compare the ultrasound-guided approach to standard ventilator care in the ICU.
BrusselsAges 18–100 - NCT05640635Recruiting
Testing inflammation changes in people on ECMO
This study looks at inflammation during ECMO (a heart-lung bypass machine) and while people are being weaned off it. It may help doctors better understand which patients are improving safely during ECMO and when to reduce support.
Tübingen, Baden-WurttembergAges 18 years+ - NCT05767671Recruiting
Breathing tube patients in ICU tested for lung inflammation treatment
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Denver, ColoradoAges 18–99 - NCT05816954Recruiting
Imaging test to predict lung injury risk in ARDS
This study looks at scan images to better predict the risk of a serious lung complication (barotrauma) in people with ARDS. It may help doctors choose safer treatment strategies in the ICU.
Catanzaro, CalabriaAges 18 years+ - NCT05822869Recruiting
Testing early EIT monitoring in people with ARDS
This trial looks at monitoring people with ARDS (a serious lung condition) very early after breathing support starts, using a technology called EIT. The goal is to see whether this early monitoring can help guide care during the first critical hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05844579Recruiting
Early breathing and mobilization support for ICU lung injury
This study looks at whether starting early movement and breathing-related care while in the ICU helps people with ARDS (a serious lung condition). You may be eligible if you recently needed a breathing machine and are expected to need it for a bit longer.
TokyoAges 16 years+ - NCT05847634Recruiting
Testing how deep sedation affects blood flow in ARDS
This study looks at whether giving deep sedation (and sometimes muscle-paralyzing medicines) changes blood flow and oxygen delivery in the brain during acute respiratory distress syndrome (ARDS). It is a pilot study, meaning it mainly aims to understand safety and gather early information.
Winnipeg, ManitobaAges 18 years+ - NCT05849779RecruitingPhase 3
Breathing sevoflurane to help prevent ARDS in ICU patients
This Phase 3 trial tests whether inhaled sevoflurane (a breathing anesthetic) can help prevent ARDS, a serious lung injury, in high-risk ICU patients who need sedation. It aims to reduce the chance of developing ARDS by using this medication during the early period on a breathing machine.
Clermont-Ferrand, Not Required For This CountryAges 18 years+ - NCT05855317Recruiting
Tests blood marker link to lung blood clots in ARDS
This study looks at a blood marker (EV-TF) to see whether it helps predict pulmonary embolism—blood clots in the lungs—in people with ARDS who are in the ICU. Results may help doctors better identify who is at higher risk.
MarseilleAges 18 years+ - NCT05898269Recruiting
Predicting fluid needs while lying face down in ARDS
This study tests a way to predict whether you will benefit from a fluid bolus (a small amount of IV fluid) while you are lying face down for ARDS. It uses continuous heart monitoring to guide or evaluate fluid decisions and may help clinicians avoid too much or too little fluid.
Clermont-FerrandAges 18 years+ - NCT05908227Recruiting
Testing nasal high-flow settings in stable preterm babies
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Mainz, Rhineland-PalatinateAges 5 months–7 months - NCT05922969Recruiting
Testing low PEEP breathing steps in ARDS care
This trial tests the safety of using lower PEEP breathing settings during care for ARDS, a serious lung condition. It may help doctors choose safer breathing support settings for people on a breathing machine.
AmiensAges 18 years+ - NCT05928052Recruiting
Spinal stimulation to help ARDS patients get off the ventilator
This study tests whether stimulating nerves in the spine can help people with severe lung injury (ARDS) breathe without a ventilator sooner. It may help shorten the time you need a breathing machine in the ICU.
Los Angeles, CaliforniaAges 18 years+ - NCT05960929RecruitingPhase 3
Breathing support for premature babies with lung distress
This Phase 3 trial tests whether InfasurfAero™ (a type of surfactant given as aerosol) works better than a sham treatment in preterm babies with respiratory distress syndrome (RDS). It aims to improve breathing in the first hours of life for babies who need CPAP.
Phoenix, ArizonaAges 7 months–8 months
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Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 220 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.