Clinical trials
Rotator Cuff Disease clinical trials
Below are recruiting rotator cuff disease clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07875556Recruiting
Shoulder repair with tissue patch for large rotator cuff tears
This trial tests a new way to repair large rotator cuff tears using a tissue patch to help the tendon heal. It might offer a better option for people whose tears are hard to fix with standard surgery.
Ho Chi Minh City, Ho Chi MinhAges 40–75 - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80 - NCT07688902Recruiting
Comparing two injection methods for partial rotator cuff tears
This study compares two ways of injecting a sugar-water solution (5% dextrose) into the shoulder to treat partial rotator cuff tears. It may help reduce pain and improve shoulder function without surgery.
AnkaraAges 18–75 - NCT07587931Recruiting
Concentric vs Eccentric Exercise for Partial Rotator Cuff Tears
This study compares two types of shoulder exercises—one where you shorten the muscle and one where you lengthen it—to see which works better for partial tears of your rotator cuff (the muscles that stabilize your shoulder). The goal is to reduce pain and improve shoulder function.
Elâzığ, MErkezAges 18–65 - NCT07428070Recruiting
Exercise program for rotator cuff shoulder pain
This trial tests if a specially designed exercise program can reduce shoulder pain related to the rotator cuff. It may help if you've had shoulder pain for more than three months.
IstanbulAges 18–75 - NCT06817616Recruiting
Rotator cuff repair with stem cells for large shoulder tears
This trial tests whether adding umbilical cord stem cells to standard arthroscopic rotator cuff repair helps heal large or massive tears better. It may be an option if you have had shoulder pain for at least three months and other treatments haven't worked.
Seoul, KoreaAges 19 years+ - NCT07374679Recruiting
Long-term safety and effectiveness of stem cells for rotator cuff disease
This study follows up with people who already received an experimental stem cell treatment for rotator cuff disease in a previous trial. It aims to check if the treatment remains safe and effective over time.
Seoul, KoreaAges 19 years+ - NCT07255534Recruiting
Digital therapy for shoulder recovery after rotator cuff repair
This trial tests a digital app-based therapy to improve shoulder function after rotator cuff repair surgery. It uses your smartphone to guide your rehabilitation exercises at home.
Seoul, Republic of KoreaAges 19 years+ - NCT07183774Recruiting
Does muscle loss affect shoulder tear patterns?
This study looks at whether sarcopenia (age-related muscle loss) affects the type of rotator cuff tear you have. You'll get a shoulder MRI to check your rotator cuff and muscle measurements.
Istanbul, ÜsküdarAges 40–75 - NCT07053566Enrolling by invitation
Back muscle strengthening for rotator cuff tendinopathy
This study tests whether strengthening a back muscle (latissimus dorsi) helps people with rotator cuff tendinopathy. You may be able to join if you have had shoulder pain for at least 3 months and meet certain medical criteria.
AnkaraAges 18–50 - NCT07005063Recruiting
Rotator cuff repair with FiberLocker patch
This trial tests a new patch, FiberLocker, to help repair a torn rotator cuff tendon. It's for people who need surgery for a full-thickness tear caused by an injury, and aims to improve healing.
Zurich, Canton of ZurichAges 40–65 - NCT06918041Recruiting
FiberLocker device to strengthen rotator cuff tear repair
This study tests a device called FiberLocker® that strengthens the repair of a torn rotator cuff tendon during keyhole surgery. It may help the tendon heal better or faster than standard surgery alone.
Chicago, IllinoisAges 30–70 - NCT05327972RecruitingPhase 2
Botox injections for painful degenerative rotator cuff disease
This Phase 2 study tests whether botulinum toxin (Botox) injections can reduce pain from long-lasting degenerative rotator cuff problems. You may be eligible if you have shoulder pain for over a month and ultrasound evidence of specific tendon irritation.
Paris, ParisAges 41 years+ - NCT06794294RecruitingPhase 1/Phase 2
Stem cell therapy for chronic shoulder pain from partial rotator cuff tear
This trial tests whether a single injection of stem cells from donated umbilical cord tissue can help people with a partial rotator cuff tear that hasn't healed with standard treatments like physical therapy or injections. If you have had shoulder pain for at least 3 months and a partial tear confirmed by MRI or ultrasound, you may be eligible.
Seoul, KoreaAges 19 years+ - NCT06677320Recruiting
What really matters in rotator cuff disease
This study looks at what it means for rotator cuff problems to be clinically important—how they affect your daily life and what counts as meaningful improvement. It helps doctors better understand your symptoms and recovery.
KırklareliAges 18 years+ - NCT06669741Enrolling by invitation
Wearable device for recovery after rotator cuff repair
This study tests whether a special wearable device (Incrediwear) can help you recover faster after rotator cuff repair surgery. It compares recovery outcomes for people who use the device after their shoulder surgery.
Denton, TexasAges 18–75 - NCT06505135Enrolling by invitationPhase 1
Stem cells for rotator cuff tear repair
This study tests whether injecting your own stem cells (taken from belly fat) during rotator cuff repair helps the tendon heal better and reduces pain. It's for people with a recent, repairable tear who are otherwise healthy.
Sønderborg, DanmarkAges 40–69 - NCT05997381Recruiting
BioBrace implant for rotator cuff tear repair
This study tests a new implant called BioBrace to help repair full-thickness rotator cuff tears during shoulder surgery. It may be a good option if you have a moderate-sized tear, have already tried non-surgical treatments, and are between 40 and 70 years old.
New Haven, ConnecticutAges 40–70 - NCT04944836RecruitingPhase 2
Testosterone supplement with rotator cuff repair
This study tests whether taking a sex hormone (testosterone) around the time of rotator cuff surgery improves healing after repair. It may help some men recover better, but it only fits people with specific tear features and health conditions.
Salt Lake City, UtahAges 40–80 - NCT03752034Recruiting
Muscle fragments after rotator cuff surgery to improve shoulder function
This study looks at whether using “muscle fiber fragments” during/after rotator cuff repair can help your shoulder work better. It targets people with a small tear in one shoulder who can follow the post-surgery follow-up plan.
Winston-Salem, North CarolinaAges 40–80 - NCT01193647Enrolling by invitation
Study genetics that may raise rotator cuff injury risk
This study looks at genetic (inherited) factors that may make some people more likely to develop rotator cuff tears. You may be able to join if you’ve had a shoulder MRI for pain or you’re a close family member of someone with a documented tear.
Salt Lake City, UtahAges 18 years+ - NCT05102968Recruiting
App-based home rehab after shoulder arthroscopy
This study tests whether using a communication app to help you do home rehabilitation after arthroscopic shoulder surgery improves recovery and function. If you have a small to medium full-thickness rotator cuff tear (or certain subscapularis tears) and can commit to follow-up for two years, you may be eligible.
Kaohsiung CityAges 20–70 - NCT05624164Recruiting
Microfracture surgery to help rotator cuff tears heal
This trial studies a specific surgical technique (microfracture) to help the rotator cuff heal after repair. You might be eligible if you have a rotator cuff tear of a certain size on MRI and have not improved with non-surgical treatments.
Nantong, JiangsuAges 18–65 - NCT07744165Recruiting
Shoulder muscle and balance study for rotator cuff tear
This study looks at how shoulder problems affect muscle strength and balance. It may help understand why shoulder pain can affect your daily activities.
Istanbul, KadıköyAges 18 years+
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Common questions
- Are there clinical trials for rotator cuff disease?
- Yes. Clin2 currently lists 73 recruiting rotator cuff disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.