Clinical trials
Rotator Cuff Disease clinical trials
Below are recruiting rotator cuff disease clinical trials, each written for real people, not researchers. We’re tracking 83 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05102968Recruiting
App-based home rehab after shoulder arthroscopy
This study tests whether using a communication app to help you do home rehabilitation after arthroscopic shoulder surgery improves recovery and function. If you have a small to medium full-thickness rotator cuff tear (or certain subscapularis tears) and can commit to follow-up for two years, you may be eligible.
Kaohsiung CityAges 20–70 - NCT05603728Recruiting
Follow-up study for Exactech shoulder implants after surgery
This study follows people who get (or already had) a shoulder replacement to see how the implant is doing over time. It may help improve future care by tracking long-term performance and safety.
Laguna Woods, CaliforniaAges 21 years+ - NCT05624164Recruiting
Microfracture surgery to help rotator cuff tears heal
This trial studies a specific surgical technique (microfracture) to help the rotator cuff heal after repair. You might be eligible if you have a rotator cuff tear of a certain size on MRI and have not improved with non-surgical treatments.
Nantong, JiangsuAges 18–65 - NCT05855759Recruiting
New graft to help repair large rotator cuff tears
This trial studies a special “acellular” (cell-free) skin-derived graft combined with healing-stimulating materials to improve healing and function after surgery for large rotator cuff tears. It may help people with serious tendon damage in the shoulder, but only if their tear type and health situation fit the study rules.
Bologna, BOAges 18–65 - NCT05894265Recruiting
Test collagen patch versus standard care after rotator cuff repair
This study compares a collagen “patch” placed during arthroscopic rotator cuff surgery versus the usual standard repair. It looks at safety and whether the patch improves healing and shoulder function after surgery.
Houston, TexasAges 18–80 - NCT06095050Recruiting
Embolization for chronic shoulder pain
This trial tests a procedure called embolization to treat long-lasting shoulder pain that hasn't improved with other treatments like physical therapy or injections. The goal is to see if blocking certain blood vessels can reduce pain and improve function.
Boston, MassachusettsAges 21–80 - NCT06272786Recruiting
Nerve Block for Recovery After Rotator Cuff Surgery
This study tests whether a nerve block (an injection to numb a nerve in the shoulder) can improve recovery after rotator cuff repair surgery. It is for people who recently had this surgery and have no other problems with their shoulder or health that might affect the results.
Kirşehir, City CentreAges 18–65 - NCT06590714Recruiting
Polmacoxib for pain after rotator cuff surgery
This trial tests if Polmacoxib, an anti-inflammatory drug, can reduce the need for stronger painkillers after rotator cuff surgery. It may help manage pain with fewer side effects.
Uijeongbu-si, Gyeonggi-doAges 18 years+ - NCT06886932Recruiting
Pain education after rotator cuff surgery
This trial tests if learning about pain before and after rotator cuff repair helps people recover better. It might help you if you have a medium-sized tear and are planning surgery.
KaramanAges 40–75 - NCT07001566Recruiting
Neck nerve issues and shoulder function after rotator cuff repair
This study looks at how neck-related nerve problems (cervical radiculopathy) affect shoulder function in people who have had rotator cuff repair surgery. It aims to understand if neck issues can slow recovery or make it harder to use your arm normally.
Istanbul, IstanbulAges 41–65 - NCT04864158Recruiting
Shoulder implant versus exercise program for damaged rotator cuff
This trial compares a shoulder implant (prosthesis) with an active exercise program for people whose rotator cuff has caused shoulder joint damage. The goal is to see which approach helps function and comfort better over time.
Aarhus NAges 60–85 - NCT07377292Recruiting
Core exercises for rotator cuff tears
This trial tests if core stabilization exercises help people with a partial rotator cuff tear (a small tear in the shoulder muscle) feel better and move easier. It may be an option if you haven't had recent treatments or injections for your shoulder.
KırşehirAges 40–60 - NCT07383038Recruiting
Mobilization with movement for rotator cuff injuries
This trial tests a gentle hands-on therapy technique called 'mobilization with movement' to help people with partial rotator cuff tears or tendinopathy. It aims to improve shoulder pain and movement.
KırşehirAges 18–65 - NCT07390396Recruiting
Shock wave therapy plus exercises for shoulder pain
This trial tests whether adding shock wave therapy to standard exercises helps people with chronic rotator cuff tendon pain. If you have had shoulder pain for over 3 months due to a confirmed tendon problem, this might be an option for you.
Minya, Menia GovernorateAges 30–55 - NCT07412184Recruiting
Wearable device rehab after rotator cuff surgery
This trial tests a wearable-device remote rehabilitation system for people who have had a first-time rotator cuff tear repaired. It may help you recover at home after surgery.
BeijingAges 18 years+ - NCT06435494Enrolling by invitation
Using patient reports to improve shoulder care across clinics
This study tests whether asking patients about their shoulder symptoms using a phone or computer app can help doctors and therapists work together to improve care. It is for adults with shoulder pain that started without a sudden injury.
Gentofte Municipality, HellerupAges 18–120 - NCT06139666Enrolling by invitationPhase 4
Liposomal bupivacaine nerve block for rotator cuff surgery
This study tests whether a long-lasting numbing medicine called liposomal bupivacaine (Exparel) works better than standard pain relief for people having rotator cuff surgery. It aims to lessen pain after surgery so you may need fewer pain pills.
Camden, New JerseyAges 18 years+ - NCT05566470Enrolling by invitation
Study of brain-muscle changes after major rotator cuff surgery
This study looks at how the brain and muscles work, along with mood and pain, in people after rotator cuff surgery for a major tear. It may help researchers understand recovery problems and psychological effects that can happen after surgery.
AnkaraAges 30–65 - NCT07076069RecruitingPhase 4
Rotator cuff repair pain study: fewer narcotics
This trial tests a mix of pain medicines (multimodal regimen) to see if it reduces the need for strong narcotics after arthroscopic rotator cuff repair. If you have a torn rotator cuff that hasn't healed with other treatments and you are scheduled for surgery, you may be able to join.
The Bronx, New YorkAges 18 years+ - NCT06868108Enrolling by invitation
Rotator cuff repair with flexible anchors: study of healing
This study follows people who had rotator cuff repair using a special stitching system with anchors (FSSA). It checks how well the tendon heals by looking at MRI scans taken about a year after surgery.
Charlotte, North CarolinaAges 18–70 - NCT07219654RecruitingPhase 2
Study of TPX-115 for partial rotator cuff tear
This study tests an experimental treatment called TPX-115 for people with a partial-thickness rotator cuff tear. It aims to see if the treatment can reduce pain and improve function compared to standard care.
La Mesa, CaliforniaAges 18 years+ - NCT06969625Recruiting
Shoulder Block for Pain Relief After Rotator Cuff Surgery
This study tests a special numbing injection (shoulder block) to see how well it controls pain after arthroscopic rotator cuff repair. If you are having this type of shoulder surgery and are generally healthy, this trial may help you recover with less pain.
Zagazig, Al SharqiaAges 21–65 - NCT06414005RecruitingPhase 2/Phase 3
TPX-115 injection for partial-thickness rotator cuff tear
This trial tests an injection called TPX-115 for people with a partial-thickness rotator cuff tear (a shoulder tendon injury that doesn't go all the way through). It may help reduce pain and improve movement if you've had shoulder problems for more than 3 months despite other treatments.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06766630RecruitingPhase 2/Phase 3
Silk mesh for rotator cuff tear repair
This trial tests a new silk-based surgical mesh to help repair large rotator cuff tears. It's for people who have not gotten better with other treatments and need surgery.
Hangzhou, ZhejiangAges 50–75
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Common questions
- Are there clinical trials for rotator cuff disease?
- Yes. Clin2 currently lists 83 recruiting rotator cuff disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.