Clinical trials
Rotator Cuff Tears clinical trials
Below are recruiting rotator cuff tears clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05855759Recruiting
New graft to help repair large rotator cuff tears
This trial studies a special “acellular” (cell-free) skin-derived graft combined with healing-stimulating materials to improve healing and function after surgery for large rotator cuff tears. It may help people with serious tendon damage in the shoulder, but only if their tear type and health situation fit the study rules.
Bologna, BOAges 18–65 - NCT05603728Recruiting
Follow-up study for Exactech shoulder implants after surgery
This study follows people who get (or already had) a shoulder replacement to see how the implant is doing over time. It may help improve future care by tracking long-term performance and safety.
Laguna Woods, CaliforniaAges 21 years+ - NCT05590494Recruiting
New treatment for partial rotator cuff shoulder tears
This trial tests a new approach for people with a partial (not full) tear of the rotator cuff, found on MRI. It may help improve shoulder function if your tear matches the study’s specific size and location rules.
Onalaska, WisconsinAges 25–75 - NCT05439850RecruitingPhase 4
Bioinductive patch for severe torn shoulder tendons
This trial studies a special patch placed during minimally invasive shoulder surgery to help heal full-thickness rotator cuff tears. It may help people whose tears are large or massive and who already tried non-surgical treatment without enough improvement.
Detroit, MichiganAges 18 years+ - NCT05400798Enrolling by invitation
Study of injected regenerative cells for rotator cuff tears safety
This study checks the long-term safety of an injection made from your own fat cells for people with a chronic rotator cuff tear. It is mainly focused on monitoring side effects and outcomes over time.
Phoenix, ArizonaAges 30–75 - NCT04944836RecruitingPhase 2
Testosterone supplement with rotator cuff repair
This study tests whether taking a sex hormone (testosterone) around the time of rotator cuff surgery improves healing after repair. It may help some men recover better, but it only fits people with specific tear features and health conditions.
Salt Lake City, UtahAges 40–80 - NCT04975581RecruitingPhase 4
Repairing a rotator cuff tear with a dermal patch
This trial studies whether repairing a rotator cuff tear using a patch made from human donor skin improves healing and shoulder function. It is for people with certain types of degenerative tears that can be fully repaired by surgery.
LeicesterAges 50–75 - NCT04831164Recruiting
Study of shoulder rotator cuff tears and genetics
This study looks at how genes and risk factors relate to rotator cuff tears by comparing people with and without these tears. It may help researchers understand why tears happen and who is most at risk.
Iowa City, IowaAges 40–85 - NCT03752034Recruiting
Muscle fragments after rotator cuff surgery to improve shoulder function
This study looks at whether using “muscle fiber fragments” during/after rotator cuff repair can help your shoulder work better. It targets people with a small tear in one shoulder who can follow the post-surgery follow-up plan.
Winston-Salem, North CarolinaAges 40–80 - NCT03617562Recruiting
Compare two surgeries for large rotator cuff tears
This trial compares two different operations to treat large, hard-to-repair rotator cuff tears. If your tear is too damaged to be repaired in the usual way, the study tests whether one surgical approach may work better than a partial repair.
Toronto, OntarioAges 18–65 - NCT01193647Enrolling by invitation
Study genetics that may raise rotator cuff injury risk
This study looks at genetic (inherited) factors that may make some people more likely to develop rotator cuff tears. You may be able to join if you’ve had a shoulder MRI for pain or you’re a close family member of someone with a documented tear.
Salt Lake City, UtahAges 18 years+ - NCT07377292Recruiting
Core exercises for rotator cuff tears
This trial tests if core stabilization exercises help people with a partial rotator cuff tear (a small tear in the shoulder muscle) feel better and move easier. It may be an option if you haven't had recent treatments or injections for your shoulder.
KırşehirAges 40–60 - NCT06237647Recruiting
Comparing injections for partial rotator cuff tears
This study compares three types of injections—steroids, PRP (platelet-rich plasma), and PRP combined with hyaluronic acid—to see which works best for partial rotator cuff tears. If you have shoulder pain from a partial tear, this trial may help find the most effective treatment for you.
Kaohsiung City, SanminAges 20–85 - NCT06794294RecruitingPhase 1/Phase 2
Stem cell therapy for chronic shoulder pain from partial rotator cuff tear
This trial tests whether a single injection of stem cells from donated umbilical cord tissue can help people with a partial rotator cuff tear that hasn't healed with standard treatments like physical therapy or injections. If you have had shoulder pain for at least 3 months and a partial tear confirmed by MRI or ultrasound, you may be eligible.
Seoul, KoreaAges 19 years+ - NCT06517680Recruiting
Tight Control for Shoulder Tendon Pain
This study tests whether a strict, well-monitored treatment plan works better for recent-onset rotator cuff tendinopathy (pain from the tendons around your shoulder). It aims to see if controlling treatment closely can help you recover faster.
AngersAges 18–65 - NCT06095050Recruiting
Embolization for chronic shoulder pain
This trial tests a procedure called embolization to treat long-lasting shoulder pain that hasn't improved with other treatments like physical therapy or injections. The goal is to see if blocking certain blood vessels can reduce pain and improve function.
Boston, MassachusettsAges 21–80 - NCT05095909Recruiting
Frozen compression at intervals vs regular icing after shoulder surgery
This trial tests whether using a special device that gives cold in pulses (intermittent cryo-compression) helps the shoulder feel better after arthroscopic rotator cuff repair compared with traditional icing. It may help with pain and recovery during the early healing period after surgery.
Plymouth, MinnesotaAges 18–70 - NCT07820592Enrolling by invitation
Pre-surgery exercises to speed recovery after rotator cuff repair
This study tests whether doing exercises before your shoulder surgery helps you recover faster and better after rotator cuff repair. If you are scheduled for arthroscopic shoulder surgery, this program might help you regain strength and movement more quickly.
TemucoAges 50 years+ - NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT06971497Recruiting
ActivBraid implant for rotator cuff repair study
This study tests a special implant (ActivBraid) to help repair a torn rotator cuff. If you have a moderate-sized tear and haven't had prior shoulder surgery, you may be able to join.
Cleveland, OhioAges 18–75 - NCT06002009Recruiting
Rotator cuff tear study: nerve function and tear size
This study looks at how the size and type of a rotator cuff tear affects the nerve that controls shoulder movement. It may help doctors understand why some tears lead to more pain or weakness.
Stoke-on-TrentAges 18 years+ - NCT07851233Enrolling by invitation
Patient education on sling use after shoulder surgery
This study looks at how different ways of teaching patients about sling use after shoulder surgery may affect their recovery. If you join, you may receive extra education materials to help you use your sling correctly.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05807854Recruiting
Surgery options for large, repairable shoulder tendon tears
This trial compares two different ways to repair a large, repairable rotator cuff (shoulder tendon) tear. It may help you understand which surgical approach leads to better recovery after non-surgical treatments have already failed.
Portland, OregonAges 60–80 - NCT05959733Recruiting
Repairing large shoulder tears with BioBrace support
This study compares two surgical approaches for fixing large, two-tendon rotator cuff tears in the shoulder, using a product called BioBrace®. It may help you understand which approach leads to better recovery and shoulder function.
Halifax, Nova ScotiaAges 18 years+
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Common questions
- Are there clinical trials for rotator cuff tears?
- Yes. Clin2 currently lists 102 recruiting rotator cuff tears studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff tears trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff tears trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.