Clinical trials
Sepsis and Septic Shock clinical trials
Below are recruiting sepsis and septic shock clinical trials, each written for real people, not researchers. We’re tracking 92 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06446947Recruiting
Blood markers for poor outcomes after sepsis in cancer surgery
This study looks at blood markers (epigenetics) to better understand why some people have a harder time recovering from a severe infection after major cancer surgery. The goal is to find early signs of poor outcomes in men aged 45–75 with post-surgery sepsis.
Marseille, Bouches du RhôneAges 45–75 - NCT06481410Recruiting
Methylene blue for severe septic shock
This trial is testing whether a medication called methylene blue can help people with severe septic shock who are already on strong blood pressure support (norepinephrine). The goal is to see if it improves survival and reduces the need for other treatments.
Hangzhou, ZhejiangAges Any age - NCT06545838Recruiting
Testing renin levels to predict septic shock severity
This trial checks if a blood test measuring renin (a kidney hormone) can help predict how severe septic shock will be and how well patients recover. It looks for early clues in ICU patients with sepsis.
MoscowAges 18 years+ - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT06572995Recruiting
Fluid monitoring during septic shock recovery
This study is for adults in the intensive care unit with septic shock (a severe infection that drops blood pressure). It looks at how well your body holds fluid and whether treatment can be safely reduced.
BrestAges 18–99 - NCT06670963RecruitingPhase 4
Epoetin alfa and iron for anemia in sepsis
This trial tests whether a combination of epoetin alfa (a medicine that boosts red blood cell production) and iron derisomaltose (an iron supplement) can safely treat anemia in people with sepsis or septic shock. It may help improve your energy and recovery.
KatowiceAges 18 years+ - NCT06709573RecruitingPhase 4
Early vs. late vasopressin for septic shock
This study compares giving vasopressin earlier vs. later to patients with septic shock who are already on norepinephrine. The goal is to see if adding vasopressin sooner helps improve blood pressure recovery.
Cleveland, OhioAges 18 years+ - NCT06786364Recruiting
Measuring blood flow waves in sepsis patients
This study uses a special light sensor to measure blood flow waves in patients with septic shock. The goal is to see if these waves can help doctors understand how severe the shock is.
Mexico City, CuauhtemocAges 18 years+ - NCT06809868Recruiting
Study of genetic elements in sepsis and aging
This trial looks at how certain genetic elements may affect the immune system in older adults with sepsis. It aims to understand why older patients may respond differently to severe infections.
San Francisco, CaliforniaAges 18 years+ - NCT06832436Recruiting
Atrial strain study in septic shock patients
This study looks at how well the upper chambers of the heart (atria) work during septic shock using a special heart ultrasound. It may help doctors understand how the heart is affected by severe infections.
SalouëlAges 18 years+ - NCT06898723RecruitingPhase 4
Shenfu injection to prevent heart problems in sepsis
This trial tests whether Shenfu injection can help prevent heart muscle damage in people with septic shock. If you have septic shock, you may be able to join this study to see if this treatment helps protect your heart.
Wuhu, AnhuiAges 18 years+ - NCT06990295Recruiting
Ultrasound spleen stimulation for sepsis shock
This trial tests if using focused ultrasound to stimulate the spleen can reduce inflammation in septic shock. It may help patients in the ICU who need strong blood pressure support.
Wuhu, AnhuiAges 18 years+ - NCT07096284Recruiting
Study of a blood oxygen ratio in septic shock
This trial tests a new way to measure oxygen levels in the blood of patients with septic shock. It may help doctors better understand how well the body is using oxygen.
Marrakesh, MarrakeshAges 18 years+ - NCT07179276Recruiting
Testing CO₂ gap to guide septic shock treatment
This trial checks if measuring the carbon dioxide gap (a sign of how well blood is flowing to organs) can help doctors improve treatment for people in septic shock. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AngersAges 18 years+ - NCT07203833Recruiting
Vasorin test for shock diagnosis and outlook
This study looks at a protein called vasorin in the blood to see if it can help diagnose and predict outcomes in people with severe shock in the ICU. It compares patients with septic shock (caused by infection) to those with shock from other causes.
AmiensAges 18 years+ - NCT07425587Recruiting
Symphony IL-6 test for sepsis in the emergency room
This trial checks if a new blood test (Symphony IL-6) can help doctors quickly identify sepsis in patients coming to the emergency room. It may speed up diagnosis and treatment for serious infections.
Gainesville, FloridaAges 22 years+ - NCT02936232Recruiting
Registry for severe sepsis and septic shock
This registry collects medical information from adults who have suspected or proven serious infection causing body organ problems. It helps researchers better understand what happens in severe sepsis and septic shock and may guide future care.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07451886RecruitingPhase 2
Fludrocortisone for septic shock
This study tests whether adding a steroid called fludrocortisone to standard care helps people with septic shock (a dangerous drop in blood pressure from infection) get better faster. If you are in the ICU, on a breathing machine, and need strong medication for your blood pressure, you may be eligible.
Hong KongAges 18 years+ - NCT07539883Recruiting
Septic Shock Treatment With Special Kidney-Filter Devices
This study looks back at how a special kidney filter called oXiris helped patients in the ICU who had septic shock (a life-threatening blood infection) and kidney failure. Researchers want to understand if this filter improved survival and recovery compared to standard treatment.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07582926Recruiting
Cortisol Levels and Outcomes in Critically Ill Infection Patients
This study examines how the body's stress hormone (cortisol) relates to survival in patients with severe blood infections in the ICU. Understanding this relationship may help doctors better predict and manage outcomes in critically ill patients.
AnkaraAges 18 years+ - NCT07597122Recruiting
Blood markers study in septic shock patients
This research study measures special blood markers (microRNAs) in patients with septic shock or critical illness to understand how the body responds to severe infection. Results may help doctors better diagnose and treat sepsis in the future.
BernAges 18 years+ - NCT07616817Enrolling by invitation
Expert Panel Study on Ultrasound Assessment of Septic Shock
This study gathers expert opinions from critical care doctors and specialists around the world who use bedside ultrasound (a portable imaging tool) to diagnose and categorize septic shock (a life-threatening infection condition). The goal is to develop standardized approaches to identifying different types of septic shock using ultrasound.
Albany, New YorkAges Any age - NCT06904001Enrolling by invitation
Early warning model for sepsis in critically ill patients
This trial is building a tool to predict sepsis, a life-threatening response to infection, in intensive care patients. It may help doctors act faster to prevent complications.
Wenzhou, ZhejiangAges 18–99 - NCT06808100Enrolling by invitation
Can a blood test predict organ failure in septic shock?
This trial is studying a blood marker called GDF-15 to see if it can predict which patients with septic shock might develop multiple organ failure. If you have septic shock and do not have certain other serious health conditions, you may be able to join.
AnkaraAges 18 years+
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Common questions
- Are there clinical trials for sepsis and septic shock?
- Yes. Clin2 currently lists 92 recruiting sepsis and septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis and septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis and septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.