Clinical trials
Spina Bifida clinical trials
Below are recruiting spina bifida clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07615686Recruiting
Spinal Cord Stimulation to Help Children with Spina Bifida Walk
This trial tests a treatment called transcutaneous spinal cord stimulation (tSCS)—gentle electrical pulses applied to the skin over the spine—to help children with spina bifida walk better and manage bladder control. The study includes children ages 4–17 who can walk short distances with help or devices.
Pittsburgh, PennsylvaniaAges 4–17 - NCT05163899Recruiting
Surgery to release an occult tethered cord
This trial studies whether a specific back surgery (cutting/releasing part of the filum terminale) helps people with an “occult” tethered cord syndrome when symptoms have not improved with medicine. It may help by reducing traction on the spinal cord to improve bladder/bowel, skin, or nerve-related symptoms.
New York, New YorkAges 2–80 - NCT07178873Recruiting
Online support program for adults with spina bifida
This study tests an online support program for adults with spina bifida to help with emotional and social well-being. It is done from home through video calls.
Bilbao, BizkaiaAges 18–75 - NCT07390318Recruiting
Bowel continence study for people with spina bifida
This study looks at how bowel management enema programs work for people with spina bifida (a type of spinal cord condition). It aims to improve continence and quality of life.
Birmingham, AlabamaAges 5 years+ - NCT07642466Recruiting
Bladder Health and Life Quality in Spina Bifida
This study asks adults and teens with spina bifida about how their bladder care affects their daily life and well-being. Your answers will help doctors better understand what matters most to patients.
London, OntarioAges 13 years+ - NCT06042140Recruiting
Umbilical cord patch for spina bifida repair before birth
This study tests whether a patch made from donated umbilical cord can help repair spina bifida in the womb using a minimally invasive fetoscopic approach. If successful, it may reduce the need for more invasive open fetal surgery.
Houston, TexasAges 18 years+ - NCT06918119Recruiting
Spinal cord stimulation for children with spina bifida
This study tests whether a special type of electrical stimulation applied to the skin over the lower spine can help improve function in children and teenagers with spina bifida. It aims to see if this treatment can make daily activities easier.
Rochester, MinnesotaAges 5–18 - NCT06025734Recruiting
Nerve stimulation for bladder control in spina bifida
This study tests whether stimulating a nerve in the leg (the tibial nerve) with a small device can help children with spina bifida who leak urine even when using a catheter. The treatment is non-invasive, like a tiny electrical patch near the ankle, and aims to improve bladder control.
Dallas, TexasAges 8–18 - NCT06041334Recruiting
Spina Bifida blood vessel study
This trial studies blood vessels in people with spina bifida using safe, non-invasive methods. It aims to better understand how the condition affects the body over time.
Rennes, CHU de RennesAges 6 years+ - NCT07136688Recruiting
Tibial nerve stimulation for kids with spina bifida and bladder issues
This trial tests if a simple, non-surgical nerve stimulation can help children with spina bifida who have bladder control problems. It may reduce the need for strong medications or catheter use.
Houston, TexasAges 4–17 - NCT03856034Recruiting
Open vs minimally invasive surgery for spina bifida baby
This study compares two ways to correct spina bifida while the baby is still in the womb: an open operation (laparotomy) versus a minimally invasive endoscopic approach (percutaneous endoscopic). The goal is to see which approach leads to better outcomes for the baby and pregnancy.
Los Angeles, CaliforniaAges 18 years+ - NCT05726591Recruiting
Robotic exoskeleton study to improve walking in children
This study looks at how safely using a pediatric robotic exoskeleton over the long term can improve how children walk. It’s for children ages 3–17 who have certain movement or spine-related conditions and who can meet walking and joint-movement requirements.
Bethesda, MarylandAges 3–17 - NCT05849285Recruiting
Testing a program to support adults with lifelong care needs
This study tests a “Transitional and Lifelong Care” program for adults who had a disability since childhood, and includes their main caregiver or support person. It aims to see how this type of care support may improve experiences and support over time.
London, OntarioAges 21 years+ - NCT06723951Recruiting
Quality of life questionnaire for spina bifida patients
This study tests a new questionnaire QUALAS to see how well it measures quality of life in Dutch people with and without spina bifida. If you have spina bifida or are a healthy volunteer, you may help validate this tool.
GroningenAges 8 years+ - NCT06828653Recruiting
Comparing 3D-printed vs standard ankle braces for walking
This study compares custom-made ankle-foot braces made with a digital 3D printing method versus the traditional plaster cast method. It aims to find out which type is more comfortable and effective for people with conditions like cerebral palsy, stroke, or spinal cord injury who need a brace to help them walk better.
Mississauga, OntarioAges 8 years+ - NCT06929572Recruiting
Umbilical cord patch for closing spine birth defects after birth
This trial tests using a patch made from a newborn's own umbilical cord to help close an open spine defect (myelomeningocele or myeloschisis) shortly after birth. The goal is to protect the spinal cord and improve healing.
Houston, TexasAges Up to 1 day - NCT06946563Recruiting
Fetoscopic surgery for spina bifida before birth
This trial tests a special fetal surgery (fetoscopic repair) to fix spina bifida before birth. It might help reduce spine and brain damage in babies with this condition.
Portland, OregonAges 18 years+ - NCT07027020RecruitingPhase 3
Bladder oxybutynin for children with spina bifida
This trial tests a liquid form of the medication oxybutynin placed directly into the bladder (via catheter) for children with spina bifida who have bladder overactivity. It may be an option if oral medications haven't worked well or caused side effects.
BesançonAges 6–17 - NCT07290556Recruiting
New standing wheelchair for kids and teens
This study tests a new kind of manual wheelchair for kids and teens that lets you stand up while moving around. It’s for people who already use a manual wheelchair and are part of a standing program.
Saint Paul, MinnesotaAges 8–17 - NCT02592291Recruiting
Using a phone app to help manage long-term health needs
This study tests a mobile phone system that helps people with long-term, complex health conditions manage daily life and get support. If you can use a smartphone and pass the study checks, you may be able to try the self-management tools.
Pittsburgh, PennsylvaniaAges 12 years+
Hear when a new Spina Bifida trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Spina Bifida trials by city
Studies with a site in or near these metro areas.
Spina Bifida trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for spina bifida?
- Yes. Clin2 currently lists 20 recruiting spina bifida studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spina bifida trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spina bifida trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.