Clinical trials
Spinal Cord Diseases clinical trials
Below are recruiting spinal cord diseases clinical trials, each written for real people, not researchers. We’re tracking 257 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02769416Enrolling by invitation
Testing new treatments for spinal cord and brain injuries
This study looks for ways to test treatments for people with spinal cord injuries and/or brain injuries. It may help researchers better understand which treatment approaches work and for whom.
Houston, TexasAges 18 years+ - NCT06999434RecruitingPhase 1
Testing a new PET scan for nerve coating damage
This study uses a special PET scan tracer to look at the protective coating of nerves in the brain. It aims to help doctors see and measure damage to this coating, which can happen in diseases like multiple sclerosis. The trial is open to healthy volunteers to test this new imaging method.
New Haven, ConnecticutAges 18–90 - NCT03624374Recruiting
Study of LBSL in people with DARS2 mutations
This trial is a natural history study, meaning it tracks how LBSL (a genetic condition) affects the brain, brainstem, and spinal cord over time. It may help researchers better understand disease patterns and provide information that could support future treatments.
Baltimore, MarylandAges Any age - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT07745712Recruiting
Testing a robotic exoskeleton for children with walking difficulties
This trial tests a robotic exoskeleton called ABLE Kids to help children with walking difficulties due to neurological or muscle conditions. It checks if the device is safe and works well. Children who meet certain size and health requirements may be eligible to participate.
Girona, GironaAges Up to 17 years - NCT07603752Recruiting
Brain implant to restore arm movement in spinal cord injury
This trial tests a wireless implant placed on the brain's surface to help people with cervical (neck-level) spinal cord injuries regain some arm and hand movement. The device reads brain signals and sends them to muscles, potentially bypassing the damaged spinal cord.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06976229RecruitingPhase 1
Stem cell therapy for recent spinal cord injury
This phase 1 trial tests a new treatment made from stem cells (XS228) for people who had a spinal cord injury 14 to 60 days ago. Doctors want to see if it's safe and if it might help with recovery.
Guangzhou, GuangdongAges 18–65 - NCT06706284RecruitingPhase 4
GLP-1 agonist for diabetes after spinal cord injury
This trial tests whether a GLP-1 agonist (a type of diabetes medicine that also helps with weight loss) is safe and effective for people with spinal cord injury and type 2 diabetes who are not on other glucose-lowering drugs.
San Antonio, TexasAges 18–70 - NCT06691165RecruitingPhase 1/Phase 2
Low oxygen therapy for blood pressure in spinal cord injury
This trial tests whether breathing low oxygen (hypoxia) can help stabilize blood pressure in people with spinal cord injuries. It's looking for participants with chronic cervical injuries to see if this therapy improves 24-hour blood pressure control.
Kelowna, British ColumbiaAges 19–65 - NCT06559618RecruitingPhase 1
Phage therapy for bladder bacteria in spinal cord injury
This trial tests whether a special virus (bacteriophage) that attacks E. coli bacteria can help control bacteria in the bladder without causing an infection. It's for people with spinal cord injury who use a catheter and have E. coli in their urine but no active infection.
St Louis, MissouriAges 18 years+ - NCT05426681RecruitingPhase 1
Glyburide to protect the spinal cord after injury
This Phase 1 trial tests whether glyburide, a drug used for blood sugar, can help protect nerve tissue after an acute spinal cord injury. It’s mainly focused on safety and early signs that the treatment might be beneficial for people with certain levels of spinal cord damage.
Lexington, KentuckyAges 18–80 - NCT05443906Recruiting
Home exercise program for people with neurodegenerative conditions
This trial studies whether a home exercise program is safe and helpful for people with certain neurodegenerative conditions, including X-linked adrenoleukodystrophy and DARS2-related disease, as well as some other similar diagnoses. You would be asked to do exercises at home and be assessed on your walking and strength/safety.
Baltimore, MarylandAges 5–75 - NCT06443151Recruiting
Blood Vessel Health After Spinal Cord Injury
This study looks at how blood vessel health is affected in people with long-term spinal cord injury (over 1 year). It tests whether blood vessel function plays a role in heart and circulatory risk.
Englewood, ColoradoAges 18–89 - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+ - NCT05968664Recruiting
Test whether new spinal cord stimulation settings improve chronic pain
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
Houston, TexasAges 22 years+ - NCT07213986Recruiting
Vibrant capsule for bowel problems after spinal cord injury
This trial tests a vibrating capsule to help people with spinal cord injury have more regular bowel movements. It might be an option if you have had a spinal cord injury for at least one year and follow a steady bowel program.
Houston, TexasAges 21 years+ - NCT06585033Recruiting
Spinal cord stimulation for pain after back surgery
This trial tests how much of the pain relief from spinal cord stimulation is due to the placebo effect. It is for people with ongoing leg pain after back surgery who have already tried other treatments without success.
ArnhemAges 18–70 - NCT06455137Recruiting
Spinal cord stimulation for spinal cord injury recovery
This trial tests whether electrical stimulation of the spinal cord can improve movement and muscle control in people with spinal cord injury. If you've had a spinal cord injury for more than a year and are between 20-70 years old, this might help improve leg function and walking.
Hualien CityAges 20–70 - NCT06172621Recruiting
Spinal cord stimulation study for ALS hand weakness
This study tests whether combining brain and spinal cord stimulation can improve hand function in people with ALS who have partial weakness but still some movement in their fingers. The goal is to see if this non-invasive approach can strengthen nerve connections.
The Bronx, New YorkAges 18–80 - NCT05305118Recruiting
Blood pressure–focused study after fresh spinal cord injury
This study looks at a treatment approach for people with a new spinal cord injury who have unstable blood pressure. It may help the team understand how to manage blood pressure problems during early recovery.
New York, New YorkAges 18–89 - NCT06351111Enrolling by invitation
Vagus nerve stimulation for spinal cord injury follow-on study
This study tests whether vagus nerve stimulation can help people with spinal cord injury improve arm, leg, bladder, or sensory function. You must have completed an earlier phase of this research to join.
Dallas, TexasAges 18–64 - NCT05921175Recruiting
Stimulation and robotic walking training for incomplete spinal injuries
This trial tests whether gentle electrical stimulation of the spinal area plus robotic gait training can improve walking function in people with a traumatic spinal cord injury who are not walking independently. It’s meant for people with incomplete injuries where some nerve signals still work, and who can safely use the robotic exoskeleton.
Singapore, SingaporeAges 21–65 - NCT05157282Recruiting
Spinal cord stimulation to improve hand function after tetraplegia
This trial tests whether a special device that stimulates the spinal cord can help people with long-lasting neck spinal cord injuries recover useful hand movement and grip strength. It may help your nervous system communicate better so daily hand tasks become easier.
Chicago, IllinoisAges 18–70 - NCT07427121Recruiting
Exercise study for healthy non-smokers on a breathing machine
This study looks at how physical therapy and exercise affect people who are on a breathing machine (mechanical ventilation). It may help researchers find better ways to help patients recover while on a ventilator.
Gainesville, FloridaAges 25–80
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Common questions
- Are there clinical trials for spinal cord diseases?
- Yes. Clin2 currently lists 257 recruiting spinal cord diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal cord diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal cord diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.