Clinical trials
Spinal Surgery clinical trials
Below are recruiting spinal surgery clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05452694Recruiting
Personalized pain relief after back fusion surgery
This trial tests a personalized plan to manage pain after lumbar (lower back) fusion and decompression surgery. It may help reduce difficult pain while guiding safe use of opioids around the time of surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT06498232Enrolling by invitation
Video game exercises after scoliosis surgery
This trial compares active video game-based exercises with standard stability training in teens who had surgery for severe scoliosis. It aims to see if fun, interactive games can improve recovery just as well as traditional stability training.
IstanbulAges 10–18 - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT06020417Recruiting
Spine screw placement using O-arm navigation
This trial tests whether using a special 3D X-ray navigation system (O-arm) helps place screws more accurately in spine surgery. It may help people with various spine problems who are having spinal fusion.
Teresina, PiauíAges 18 years+ - NCT06719037Recruiting
Comparing two spine surgeries for lower back narrowing
This study compares two different surgical techniques – one using a small camera (endoscopic discectomy) and the other a traditional open approach (microdiscectomy) – to treat narrowing in the lower spine. It helps find which method may be better for relieving pain and improving function.
Jinan, ShandongAges 18–80 - NCT05110833Enrolling by invitation
Study dosing effects during monitored neck or chest spine surgery
This trial studies whether different medication dosing during monitored neck or upper chest spine surgery leads to better outcomes. You might help doctors figure out the most effective dosing approach for this type of surgery.
Minneapolis, MinnesotaAges 18 years+ - NCT03715517Recruiting
Spinal anesthesia to improve recovery after liver surgery
This trial studies whether using spinal/epidural anesthesia during liver tumor removal surgery can help people recover better and with less pain. It compares this approach to standard general anesthesia care to see if recovery is smoother.
Winnipeg, ManitobaAges 18 years+ - NCT07020390Recruiting
How anesthesia affects recovery after prostate surgery
This trial compares different anesthesia methods to see which helps patients recover better after HOLEP surgery for an enlarged prostate. Results could help choose the best anesthesia for future patients.
Melikgazi, KayseriAges 18 years+ - NCT07078201RecruitingPhase 4
Comparing two pain meds in spinal anesthesia for leg surgery
This study compares two medicines (dexmedetomidine and fentanyl) added to a spinal numbing shot for people having planned leg or knee surgery. The goal is to see which one works better to keep your blood pressure stable, and to make the numbing last while keeping you comfortable.
Port SaidAges 20–60 - NCT04631471RecruitingPhase 3
Ibudilast for spinal cord pressure from neck wear
This Phase 3 study tests ibudilast, a medicine, to see if it can improve symptoms in people whose neck arthritis has started compressing the spinal cord. You would still have your usual surgery to relieve the pressure, and then take the study medicine to see if recovery and function improve.
CambridgeAges 18–80 - NCT07467356RecruitingPhase 3
Nerve blocks for easier positioning before hip surgery
This study compares two different numbing injections (nerve blocks) to see which one helps you get into position more easily for spinal anesthesia before hip surgery. The goal is to make the procedure less painful and more comfortable.
Banhā, ElqalyoubeaAges 18 years+ - NCT07217964Enrolling by invitation
Study of natural protein for spinal fusion surgery
This trial is testing a natural protein material used during spinal fusion surgery to treat lower back pain caused by worn-out discs. It may help patients who haven't gotten better with other treatments and need surgery on up to four levels of the lower spine.
New York, New YorkAges 18 years+ - NCT06342765Recruiting
Safety of SpineVision posterior fixation systems in thoracolumbar spine
This trial checks how well the SpineVision Lumis, Plus, or Ulis spine fixation systems work and stay safe in the lower back and mid-back area. It is for people who already have one of these systems implanted.
BayonneAges 18 years+ - NCT07221682RecruitingPhase 2/Phase 3
Comparing two nerve block methods for lower leg surgery
This study compares two ways of giving a nerve block (fascia iliaca block) to help with positioning for spinal anesthesia and pain relief after lower leg surgery. The goal is to see which method works better for making patients more comfortable.
Sāhīwāl, Punjab ProvinceAges 30–60 - NCT06469073Recruiting
Nerve block for pain after heart valve surgery
This study tests a special nerve block (ultrasound-guided) to see if it can better control pain after heart valve replacement surgery. It may help you recover more comfortably if you are having your first mitral or aortic valve replacement.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07687290Recruiting
Comparing two nerve blocks for hip fracture pain before spinal anesthesia
This trial tests two types of nerve blocks to see which one works better for managing pain while positioning hip fracture patients before they receive spinal anesthesia. The goal is to find a more comfortable way to prepare for surgery.
CairoAges 18–70 - NCT06733025Recruiting
Comparing surgery and Botox for arm spasticity
This trial compares two treatments—Botox injections or surgery—for arm and hand spasticity after a stroke, brain injury, or spinal cord injury. It may help you decide which option works best for you.
MölndalAges 18 years+ - NCT05273879Recruiting
Testing whether one-level fusion is needed after lumbar decompression
This trial compares outcomes after decompression surgery for one affected area in the lower back, with and without adding spinal fusion. It may help patients avoid unnecessary extra surgery—or ensure fusion is used when it’s needed.
Moscow, MoscowAges 45–75 - NCT07002580Recruiting
Knee surgery pain relief: nerve block comparison
This study compares two types of nerve blocks (iPACK and adductor canal block) to see which provides better pain relief after arthroscopic knee surgery. It may help you have less pain and recover faster.
SakaryaAges 18–50 - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07404982RecruitingPhase 2
Speeding Recovery from Spinal Anesthesia After Joint Surgery
This trial tests a way to make the leg numbness and weakness from spinal anesthesia wear off faster after joint replacement surgery. Researchers use a small tube (catheter) placed in your spine during the procedure to reverse the muscle block sooner.
Boston, MassachusettsAges Any age - NCT06119542Recruiting
GlycOrtho: Endothelial damage in major spine surgery
This study looks at how major spine surgery affects the inner lining of blood vessels. It measures a substance called syndecan-1 in the blood to understand this damage.
Bologna, BOAges 12–75 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+
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Common questions
- Are there clinical trials for spinal surgery?
- Yes. Clin2 currently lists 132 recruiting spinal surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.