Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 264 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT06374342Recruiting
Bone substitutes study after surgery follow-up
This study follows patients who receive a Teknimed bone substitute during surgery for bone defects. It collects data on how well these bone fillers work in real-world use.
Mainvilliers, Eure et LoirAges 18 years+ - NCT06383949Recruiting
Real-world study of Synergy Disc implant
This study follows people who receive a Synergy Disc implant to treat neck pain or nerve problems. It collects real-world information on how well the disc works and how safe it is over time.
DublinAges 21 years+ - NCT06453798Recruiting
Neck exercises with nerve gliding for pinched nerve in neck
This study tests whether a combination of neck exercises and nerve gliding (gentle movements to help the nerve move freely) can reduce arm pain and other symptoms from a pinched nerve in the neck. If you have this condition and haven't had recent treatment or surgery, you may be eligible.
Qinzhou, GuangxiAges 18–65 - NCT06485206Recruiting
Hybrid disc replacement and fusion for two-level neck disease
This study tests a combination of a disc replacement (Mobi-C) and a spinal fusion (ACDF) for people with degenerative disc disease at two levels in the neck. The goal is to see if this approach is safe and effective for relieving pain and nerve symptoms.
Sacramento, CaliforniaAges 22–69 - NCT06490887Recruiting
Spine unit modeling with high-throughput analysis (SUIT)
This study looks at cells from people with degenerated discs or from donated fat or placenta tissue. It aims to understand how these cells work and might help develop new treatments for back pain.
Milan, MIAges 18–60 - NCT06511765RecruitingPhase 3
Nerve block for acute lower back pain: a pilot study
This study tests whether a single injection of a numbing medicine (ropivacaine) into the muscles of the lower back can quickly relieve sudden, severe back pain that has lasted less than a week. The goal is to see if this nerve block can help when standard pain pills aren't working.
Saint-HerblainAges 18 years+ - NCT06528288Recruiting
Numbing injection for pain relief after back fusion surgery
This study tests whether a special numbing injection (called an erector spinae plane block) given near the spine during surgery can reduce pain after lumbar fusion. If you qualify, you might have less pain and need fewer painkillers after your operation.
Worcester, MassachusettsAges 18 years+ - NCT06536478Recruiting
Exercise for posture and flexibility in Parkinson's disease
This study tests whether a special exercise program can improve your posture, flexibility, and spine health. It is designed for people with mild to moderate Parkinson's disease who are stable on their medications.
HsinchuAges 30–85 - NCT06540885RecruitingPhase 4
Comparing two nausea drugs for scoliosis spine surgery
This trial compares two medications, palonosetron and granisetron, to see which is better at preventing nausea and vomiting after spine surgery for scoliosis. These drugs may help you feel less sick after your operation.
Pantai Valley, Kuala LumpurAges 10 years+ - NCT06570577Recruiting
Nerve block for pain after cervical spine surgery
This trial tests whether a nerve block can reduce the need for opioid pain medication after back-of-neck spine surgery. It may help patients have better pain control with fewer side effects.
Stony Brook, New YorkAges 18–75 - NCT06612853Recruiting
Sleep Quality Scale Validation for Spine Patients
This study tests a single question about sleep quality to see if it works well for people with spine problems. You will fill out a simple questionnaire and may help improve how sleep is measured in future spine care.
Zurich, Canton of ZurichAges 14 years+ - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06652061Recruiting
AI model to predict bone density from X-ray
This trial is testing an artificial intelligence (AI) model that uses X-ray images to predict bone density. If you have X-rays and a bone density scan, the AI may help doctors screen for osteoporosis without extra tests.
DhakaAges 18 years+ - NCT06659055Recruiting
Bone density comparison: EOS X-ray vs standard DXA scan
This study checks if a new low-dose X-ray system (EOSedge) gives the same bone density measurements as the standard DXA scan. It is for adults getting spine or whole-body X-rays as part of their care, or healthy volunteers willing to have research scans.
Phoenix, ArizonaAges 20 years+ - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT03506334Enrolling by invitation
Tether surgery to treat pediatric spine curvature
This study looks at a surgical method (an “anterior vertebral body tether”) to help straighten the spine in growing children with certain types of scoliosis. It aims to see how well the tether system works over the next 2 years, compared with expected progress without the surgery.
Rochester, MinnesotaAges 10–16 - NCT06745791Recruiting
Testing a new spine MRI technique (BoneMRI)
This study is testing a new MRI technique called BoneMRI that may show bones more clearly than standard MRI. If you already need both a CT and an MRI of your spine, your scans could be used to compare this new method with the regular ones.
GhentAges 12 years+ - NCT06766240Recruiting
MRI for low back pain in middle-aged women
This trial is studying how well MRI can evaluate low back pain in women between 40 and 60 years old. It may help doctors better understand the cause of your pain.
SohagAges 40–60 - NCT06776003Recruiting
Mobility after vertebroplasty vs sham for spine fractures from osteoporosis
This trial compares a procedure called vertebroplasty (injecting bone cement into the broken bone) with a sham (fake) procedure to see how it affects your ability to move and be active. It's for people with recent painful spinal fractures caused by weak bones (osteoporosis).
KoldingAges 50 years+ - NCT06785350Recruiting
Smallest effective steroid dose for spine surgery pain
This study tests whether a very small amount of a steroid (betamethasone) placed around the surgical cut can help control pain after spine surgery. It aims to find the lowest dose that still works well, so patients may need fewer painkillers and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–65 - NCT06830811Recruiting
Bone Density Measurement Using a Full-Spine X-ray
This study uses a special low-dose X-ray system (EOSedge) to measure bone mineral density while you have a routine full-spine or whole-body X-ray. It aims to see if EOS can give doctors bone health information without needing a separate DXA scan.
Fishers, IndianaAges 20 years+ - NCT06839300Recruiting
Blood biomarkers in spinal cord injury study
This study is looking for people with a spinal cord injury from a blunt force (not a penetrating injury like a gunshot or stab wound) to see if certain substances in the blood (called biomarkers) can help doctors understand the injury better and predict recovery. It involves an initial blood sample within 24 hours of the injury and follow-up assessments.
Milwaukee, WisconsinAges 19 years+
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 264 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.