Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03513731Recruiting
Regenerative fat cell injection for facet joint arthritis pain
This trial tests whether injecting regenerative cells made from your body’s fat can reduce pain from facet joint osteoarthritis in the low back. It focuses on people whose pain has lasted months and did not improve with standard care, after a positive diagnostic injection test.
Deerfield Beach, FloridaAges 18–75 - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06626503RecruitingPhase 3
Pain medicine study for children having spine surgery
This study tests a pain medicine (methadone) for children and teens having spine fusion surgery for scoliosis. It aims to see if it helps control pain safely.
Indianapolis, IndianaAges 10–18 - NCT06570577Recruiting
Nerve block for pain after cervical spine surgery
This trial tests whether a nerve block can reduce the need for opioid pain medication after back-of-neck spine surgery. It may help patients have better pain control with fewer side effects.
Stony Brook, New YorkAges 18–75 - NCT06552507Recruiting
Duraplasty for severe neck spinal cord injury
This trial tests a surgery called duraplasty (widening the protective covering of the spinal cord) for people with severe neck spinal cord injuries. It aims to see if this extra procedure helps improve recovery compared to standard surgery alone.
Taoyuan, TaiwanAges 18 years+ - NCT06528288Recruiting
Numbing injection for pain relief after back fusion surgery
This study tests whether a special numbing injection (called an erector spinae plane block) given near the spine during surgery can reduce pain after lumbar fusion. If you qualify, you might have less pain and need fewer painkillers after your operation.
Worcester, MassachusettsAges 18 years+ - NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT06511765RecruitingPhase 3
Nerve block for acute lower back pain: a pilot study
This study tests whether a single injection of a numbing medicine (ropivacaine) into the muscles of the lower back can quickly relieve sudden, severe back pain that has lasted less than a week. The goal is to see if this nerve block can help when standard pain pills aren't working.
Saint-HerblainAges 18 years+ - NCT06498232Enrolling by invitation
Video game exercises after scoliosis surgery
This trial compares active video game-based exercises with standard stability training in teens who had surgery for severe scoliosis. It aims to see if fun, interactive games can improve recovery just as well as traditional stability training.
IstanbulAges 10–18 - NCT06374342Recruiting
Bone substitutes study after surgery follow-up
This study follows patients who receive a Teknimed bone substitute during surgery for bone defects. It collects data on how well these bone fillers work in real-world use.
Mainvilliers, Eure et LoirAges 18 years+ - NCT06492057Enrolling by invitation
EMS muscle training for astronauts in space
This trial tests if a special muscle stimulation device called EMS can help astronauts stay fit during spaceflight. It may prevent muscle loss in zero gravity.
Mitte, State of BerlinAges 40–60 - NCT06367582Recruiting
Study of Teknimed spine cements outcomes
This study is checking how well certain spine cements (used to stabilize broken vertebrae) work in real life. If you are 18 or older and have had or will have a TEKNIMED cement procedure, you may be able to join.
Strasbourg, Bas-RhinAges 18 years+ - NCT06463262Recruiting
Personalized markers for chordoma before surgery and radiation
This trial tests whether analyzing blood and tumor samples before and after radiation and surgery can help find personalized markers for chordoma. It is for patients with chordoma of the skull base, spine, or sacrum who will receive radiation before surgery.
Baltimore, MarylandAges 18 years+ - NCT06475365Enrolling by invitation
Salt water gargling after neck surgery to help swallowing
This study tests whether gargling with salt water after multi-level neck fusion surgery can improve swallowing recovery. If you are having this surgery, the trial aims to find a simple, low-cost way to protect your swallowing function.
Los Angeles, CaliforniaAges 18–80 - NCT06407427Recruiting
Mobile app for recovery after hip, knee, or spine surgery
This study tests whether a mobile app can help with physical therapy after common bone or joint surgeries. You may qualify if you recently had a hip fracture, hip or knee replacement, or spine surgery without paralysis. The app guides your exercises at home.
New Haven, ConnecticutAges 18 years+ - NCT06391242RecruitingPhase 3
Comparing radiation treatments for painful bone metastases
This trial compares two types of radiation therapy—standard palliative radiation and a more targeted high-dose treatment (SBRT)—to see which better relieves pain from bone metastases that have spread outside the spine. It is for people with solid tumors who have a painful bone spot and are expected to live at least 6 months.
Calgary, AlbertaAges 18 years+ - NCT06383949Recruiting
Real-world study of Synergy Disc implant
This study follows people who receive a Synergy Disc implant to treat neck pain or nerve problems. It collects real-world information on how well the disc works and how safe it is over time.
DublinAges 21 years+ - NCT06368245Recruiting
Study on extra rods for long spinal fusion surgery
This study looks at whether adding extra rods during a long spinal fusion surgery helps the fusion last longer. It is for adults aged 45 and older who had this type of surgery between 2014 and 2020.
Redwood City, CaliforniaAges 45 years+ - NCT06355791Recruiting
Study of the Minuteman device for spine fusion
This study looks at how well the Minuteman device works for people with chronic low back pain and leg symptoms caused by aging spine conditions. It tests if the device helps patients move better after surgery.
Newnan, GeorgiaAges 18 years+ - NCT06293157Recruiting
Carbon fiber screws for spinal cancer treatment
This trial tests if carbon fiber screws are better for stabilizing the spine when cancer has spread there. It may help patients who are getting special radiation therapy (SBRT) for spinal tumors.
BydgoszczAges 18 years+ - NCT05657548Recruiting
Posture study in sitting for children with cerebral palsy
This study measures the way a child’s pelvis and spine sit and hold posture while seated. It is meant to improve understanding of posture needs in children with cerebral palsy and help guide care.
NîmesAges 4–17 - NCT04628663Recruiting
Dexmedetomidine and eye pressure during spine surgeries
This study looks at whether a specific anesthesia-related medicine (dexmedetomidine) affects eye pressure during planned spine operations done with the patient lying face-down under general anesthesia. It may help doctors choose safer anesthesia to reduce risks related to eye pressure changes.
Athens, AtticaAges 18–90 - NCT06240221Enrolling by invitation
Tracking real-world use of the Saber-C cervical fusion device
This registry tracks how the Saber-C implant works in real-life neck surgeries. It gathers information to help doctors understand outcomes for people like you.
Paducah, KentuckyAges 18 years+ - NCT06202443Recruiting
Physical therapy timing after neck surgery
This study looks at whether starting physical therapy soon after ACDF neck surgery helps people recover better. It compares early physical therapy to standard care.
Honolulu, HawaiiAges 18–75
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 253 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.