Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05856539Recruiting
Numbing nerve block during minimally invasive low back surgery
This trial tests whether an “ESP block” (a numbing injection near the spine) can help control pain during minimally invasive low back fusion surgery. If you’re having this surgery, the goal is to improve comfort and reduce pain medicine needs.
New York, New YorkAges 18–80 - NCT06119542Recruiting
GlycOrtho: Endothelial damage in major spine surgery
This study looks at how major spine surgery affects the inner lining of blood vessels. It measures a substance called syndecan-1 in the blood to understand this damage.
Bologna, BOAges 12–75 - NCT06100172Recruiting
Ear Stimulation After Back Surgery
This study tests whether a gentle electrical stimulation placed on the ear (tAuricular Neurostimulation) can help reduce pain and improve recovery after lumbar spine surgery. It is for people who are already scheduled for a lumbar fusion or laminectomy and want to see if this non-invasive approach can ease their post-surgery discomfort.
Dallas, TexasAges 18–85 - NCT06075966Enrolling by invitation
A new surgery for lumbar disc disease without fusion
This trial tests a surgical technique that treats a damaged disc in your lower back without permanently fusing the bones together. It may be an option if you have had at least 3 months of other treatments like physical therapy or medication and they have not helped enough.
Jinan, ShandongAges 18–85 - NCT04115254Recruiting
MRI-guided focused radiation for certain tumors
This study tests a type of high-precision radiation guided by MRI pictures to treat certain cancers. It may help doctors deliver radiation more accurately while avoiding nearby healthy tissue, but you must be able to safely complete an MRI scan and meet tumor-size and health requirements.
Boston, MassachusettsAges 18 years+ - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT06024785Recruiting
Vertebropexy trial for lumbar spine surgery
This trial compares a new surgical technique called vertebropexy to standard fusion surgery for people with lower back problems like spinal canal narrowing or slipped vertebrae. The goal is to see if vertebropexy works as well or better with less recovery time.
Zurich, Canton of ZurichAges 18 years+ - NCT06020508Recruiting
Light device to help place epidural needles
This trial tests a new device that uses light to help doctors place an epidural needle more accurately in your lower back. It may make the procedure safer and more comfortable.
New York, New YorkAges 18–99 - NCT05981222Enrolling by invitation
Osteo Match vs. PEEK cages for spinal fusion in osteoporosis
This study compares two types of cages used in spinal fusion surgery for people with osteoporosis. It aims to see if one type leads to better bone healing and stability.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05944354Enrolling by invitation
Wearable system to study spine health for military readiness
This study tests whether a wearable setup can measure spine health during training and daily movement. It may help improve how military members with or without neck or low back pain are monitored and supported.
Luke Air Force Base, ArizonaAges 18–64 - NCT05880212Recruiting
STOPS low back and leg pain approach for Bangladesh
This trial tests a specific physiotherapy program (“STOPS approach”) for people with long-lasting low back pain or leg pain from the back. It aims to see if the structured treatment, delivered by trained physiotherapists, improves pain and function over about 10 weeks.
Dhaka, UttaraAges 18–65 - NCT05895968Recruiting
Barbed Suture for Obese Patients Having Neck Surgery
This trial tests a special type of stitch (called barb suture) used during back-of-neck surgery. It is for people who are obese and need surgery for cervical spinal problems, to see if it helps recovery.
Xi'an, Shannxi ProvinceAges 28–85 - NCT05866419Recruiting
Study of a port and catheter system for spinal muscular atrophy
This study tests a new device called the ThecaFlex DRx System, which is a small port and catheter placed under the skin to deliver Spinraza directly into spinal fluid—instead of needing repeated spinal taps. The device aims to make receiving medication easier and safer for people with SMA.
Phoenix, ArizonaAges 3 years+ - NCT05776771Recruiting
Spine movement study for people with back or neck pain
This study measures how your spine and back/neck move using motion testing and equipment. It may help researchers better understand differences between people with spine pain and people without.
Columbus, OhioAges 18 years+ - NCT05746325Recruiting
Tumor-pulse device for spinal cancer fluid spread
This trial tests whether Tumor Treating Fields (a non-surgical device that delivers treatment signals to cancer cells through the scalp/skin) can help people whose breast or lung cancer has spread into the fluid around the spine and brain. It focuses on people who have cancer cells found in spinal fluid and can safely use the device most of the day.
Jacksonville, FloridaAges 18 years+ - NCT05709782RecruitingPhase 2
MR-guided targeted radiation for limited-spine spinal metastasis
This Phase 2 study tests an MRI-guided radiation machine (an MR LINAC) to deliver very focused treatment to spine tumors. It may help by improving accuracy while treating up to a small number of spine levels affected by cancer.
Houston, TexasAges 18 years+ - NCT05534321RecruitingPhase 1/Phase 2
Preventive radiation for high-risk spinal bone metastases
This trial tests whether preventive (before serious problems happen) radiation to the spine can help people with high-risk, mostly symptom-free bone metastases. It may reduce the chance of pain escalation or dangerous complications from cancer in the spine.
Miami, FloridaAges 18 years+ - NCT05419518RecruitingPhase 2
Higher-dose radiation to ease pain from metastatic tumors
This Phase 2 study tests whether a stronger (higher-dose) radiation plan can better reduce pain from tumors that have spread to bone or other areas. It’s meant to help people live more comfortably by targeting painful spots while avoiding certain high-risk situations.
Hamilton, New JerseyAges 18 years+ - NCT05329129Recruiting
Spine surgery registry to track recovery with bone graft
This study follows people who are having spinal fusion surgery using an OssDsign bone graft. It collects health and scan information over time to better understand recovery and outcomes after surgery.
Fresno, CaliforniaAges 21 years+ - NCT05317026Recruiting
Test adding cement injection to SBRT for spine pain
This study tests whether adding a vertebroplasty procedure (a cement injection to stabilize a spine bone) to standard SBRT radiation can reduce pain from spinal metastases. It may help people with painful, possibly unstable spine lesions by improving early pain relief.
Montreal, QuebecAges 18 years+ - NCT05299736Enrolling by invitation
Study of the effects of boat rides on onboard crew
This study looks at how being on high-speed boats affects people who serve as crew or passengers for work. It’s for volunteers who are onboard in a professional role.
GothenburgAges 17–70 - NCT05281757Recruiting
Follow-up safety check for Ennovate complex in adults
This study collects safety and imaging (radiology) follow-up information from people who used the Ennovate® Complex for a specific medical reason. It helps confirm the device works well and is safe in real-world use.
BrnoAges Any age - NCT05305430Recruiting
Synergy cervical disc data study after neck surgery
This study collects real-world information about people who get the Synergy cervical disc implant after neck surgery for nerve or spinal cord pressure. It may help doctors understand how well the implant works in everyday care and what outcomes to expect.
Windsor, VictoriaAges 21 years+ - NCT05071144Recruiting
Registry for children getting robotic spine surgery
This trial registry collects information about kids and teens with spine deformities who are scheduled for robotic or navigation-assisted surgery (sometimes using custom rods). It may help doctors improve these advanced techniques over time.
Los Angeles, CaliforniaAges birth–21 years
Hear when a new Spine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 253 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.