Clinical trials · Massachusetts
Stroke clinical trials in Massachusetts
We’re tracking 46 recruiting stroke studies with a site in Massachusetts — including Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07172464Recruiting
Study of a new device to close a hole in the heart after a stroke
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
Boston, MassachusettsAges 18–65 - NCT07349030Recruiting
Fall risk intervention for stroke patients in rehab
This trial tests a program to help stroke patients in inpatient rehab reduce their risk of falling. It uses a stepping and obstacle test to identify who is at risk and then provides an intervention to improve balance and mobility.
Boston, MassachusettsAges 45–85 - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Boston, MassachusettsAges 18 years+ - NCT02896348Recruiting
Home therapy training for hand function after stroke
This trial tests a physio-and-neuro “platform” to help retrain hand movement at home in people who are at least 6 months out from a stroke. It may help improve hand function and confidence doing daily tasks using an at-home retraining program.
Boston, MassachusettsAges 21–80 - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Boston, MassachusettsAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Boston, MassachusettsAges 22–85 - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Springfield, MassachusettsAges 18 years+ - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Springfield, MassachusettsAges 18 years+ - NCT04851886Recruiting
Vision tool to guide robot therapy for stroke arm posture
This trial tests a vision-based system that detects your arm and posture during robot-assisted upper-arm therapy after a prior stroke. It may help the robot guide treatment more safely and accurately based on your movements and positioning.
Charlestown, MassachusettsAges 18–80 - NCT04187131Recruiting
AR brain tests and rehab for stroke neglect
This trial tests an augmented reality (AR) system to find and treat “neglect” after an acute stroke. If you qualify, it may help assess attention problems and guide rehabilitation exercises.
Boston, MassachusettsAges 18 years+ - NCT05085210Recruiting
Brain stimulation to improve parts of lost vision
This study tests whether a noninvasive brain stimulation treatment (tRNS) plus visual training can improve visual field problems after a stroke. It may help some people regain better visual perception in the area they lost.
Boston, MassachusettsAges 18–80 - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Burlington, MassachusettsAges 18 years+ - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
Boston, MassachusettsAges 60 years+ - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Boston, MassachusettsAges 18 years+ - NCT06511934Recruiting
BrainGate2 tablet trial for tetraplegia
This trial tests a brain-computer interface (BrainGate2) system for people with tetraplegia (paralysis of all four limbs). It aims to see if the system can help you control a tablet computer using only your brain signals. This is for people who were already in the BrainGate2 study.
Boston, MassachusettsAges 18–80 - NCT06982339Recruiting
Beat the Heat Boston study
This study provides free air conditioning units to older adults in certain Boston neighborhoods who don't have AC. It aims to see if cooling homes can help with heat-related health risks for people with certain chronic conditions.
Boston, MassachusettsAges 55–95 - NCT07091851Recruiting
Blood pressure support group for stroke survivors
This study tests whether a group-based program can help people with high blood pressure and a recent mild to moderate stroke better manage their blood pressure. You'll work with a team and use online tools to keep your blood pressure in a healthy range.
Boston, MassachusettsAges 35 years+ - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Boston, MassachusettsAges 18–80 - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Boston, MassachusettsAges 22–75 - NCT06451757RecruitingPhase 3
A trial of sonlicromanol for mitochondrial disease
This trial tests a new medicine, sonlicromanol, for people with a specific type of mitochondrial disease (caused by the m.3243A>G mutation) who also have chronic fatigue and muscle weakness. The goal is to see if it helps improve symptoms and daily function.
Boston, MassachusettsAges 18 years+ - NCT07519876Recruiting
Blood Clots in the Lungs and Heart Shunts Study
This study looks at whether people with blood clots in their lungs have hidden holes in their hearts that let blood bypass normal circulation. Researchers will use imaging tests to understand this connection and see if it affects how patients do.
Boston, MassachusettsAges 18 years+ - NCT05997914Enrolling by invitation
Storytelling to reduce stroke risk in African Americans with atrial fibrillation
This study tests whether a storytelling program can help African American patients with atrial fibrillation start taking blood thinners as recommended by their doctor. The goal is to reduce stroke risk and improve health outcomes.
Worcester, MassachusettsAges 18 years+
Stroke trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting stroke studies listed above.
- Massachusetts General Hospital · 8 studies
- Boston Medical Center · 4 studies
- Tufts Medical Center · 4 studies
- Spaulding Rehabilitation Hospital · 3 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Brigham and Women's Hospital · 2 studies
- Lahey Hospital and Medical Center · 2 studies
- UMass Memorial Medical Center · 2 studies
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Massachusetts?
- Yes. We're currently tracking 46 recruiting stroke studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.