Clinical trials · Pennsylvania
Stroke clinical trials in Pennsylvania
We’re tracking 54 recruiting stroke studies with a site in Pennsylvania — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT04897334Recruiting
Brain stimulation plus rehab to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment, combined with rehabilitation, can improve thinking and other “neurocognition” problems after a recent stroke. It may help people whose thinking has been affected by stroke within the past month.
Philadelphia, PennsylvaniaAges 18–90 - NCT04286516Recruiting
Brain and robot training for arm movement after stroke
This study tests whether brain stimulation and robotic/arm training can improve arm movement in people who had a stroke. It may help strengthen movement and coordination by targeting brain pathways related to arm control.
Pittsburgh, PennsylvaniaAges 45–90 - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Allentown, PennsylvaniaAges 18–70 - NCT03317860Recruiting
Improving care for neglect after stroke
This study tests better ways to measure and treat a condition called neglect, where stroke survivors ignore one side of their world. It may help you regain more use of your arm if you have had a stroke at least 3 months ago and have some arm movement but still find it hard to pay attention to one side.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07592221Recruiting
Electrical Stimulation for Foot Drop After Stroke
This study tests a combination of two types of electrical stimulation to help improve foot drop (difficulty lifting your foot when walking) in people who've had a stroke. The goal is to help you walk more naturally and safely.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07568301Enrolling by invitation
Music and nature self-care for brain injury survivors
This study explores whether music and nature-based activities can help people who have experienced brain injuries (like stroke or traumatic brain injury) and their caregivers manage stress and improve wellbeing. You and a care partner would participate together in the program.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07401186Recruiting
Stimulation to Improve Sensory Pathways in the Brain and Spine
This study tests whether using electrical stimulation during neck surgery can help improve how the brain and spinal cord process sensory information. It may offer new ways to help people with stroke-related weakness.
Pittsburgh, PennsylvaniaAges 21–75 - NCT07331896Recruiting
Attention Training for Stroke Survivors with Spatial Neglect
This study tests a strategy-training program to help people who have had a stroke and struggle with spatial neglect (trouble paying attention to one side). The program is designed to improve attention and daily function. Participation involves coming to the University of Pittsburgh for training sessions.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Philadelphia, PennsylvaniaAges 18–80 - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07056361Recruiting
Testing brain stimulation for better movement in tremor and Parkinson's
This study tests whether stimulating specific brain areas (VOP/VIM) during deep brain stimulation surgery can improve movement and muscle control. It includes people with essential tremor or Parkinson's disease who are already scheduled for this surgery.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06968663RecruitingPhase 2
Brain stimulation with speech therapy for recent stroke aphasia
This study tests if adding a non-invasive brain stimulation technique (transcranial magnetic stimulation) to language therapy can improve speech recovery in people who had a stroke 2 to 6 weeks ago and now have aphasia (trouble speaking or understanding language).
Philadelphia, PennsylvaniaAges 18–85 - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Hershey, PennsylvaniaAges 18–70 - NCT06842745RecruitingPhase 2
Brain stimulation plus language therapy for mild aphasia
This study tests whether combining brain stimulation (TMS) with language therapy can help people with mild aphasia after a stroke. It aims to improve speaking and understanding.
Philadelphia, PennsylvaniaAges 40–85 - NCT06632587Recruiting
Early vs. late skull replacement after brain surgery
This trial compares putting the skull piece back early (around 8 weeks after the initial surgery) versus later (after 8 weeks) in people who had a hemicraniectomy for high brain pressure. The goal is to see which timing leads to better outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06368648Recruiting
Study of a new forehead sensor for brain pressure monitoring
This study tests a new sensor that measures brain pressure from outside the head. It is for people who are already in the hospital getting their brain pressure and blood pressure monitored continuously.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Pittsburgh, PennsylvaniaAges 22–85 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06092814Recruiting
Brain stimulation to boost language after stroke
This study tests whether a gentle electrical current (tACS) applied to the scalp can improve language abilities in people with aphasia after a stroke. Healthy volunteers are also needed as a comparison group.
Philadelphia, PennsylvaniaAges 18–85 - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Pittsburgh, PennsylvaniaAges 18–80 - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Hershey, PennsylvaniaAges 18 years+ - NCT05653466RecruitingPhase 2
Telehealth therapy schedule for stroke-related aphasia patients
This trial tests an approach that adjusts therapy scheduling for people with long-lasting (over 6 months) language problems after a stroke. It may help some patients by matching the therapy timing to what works best for them.
Pittsburgh, PennsylvaniaAges 18 years+
Stroke trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting stroke studies listed above.
- University of Pennsylvania · 4 studies
- University of Pittsburgh · 4 studies
- Hospital of the University of Pennsylvania · 2 studies
- VA Pittsburgh Healthcare System · 2 studies
- Duquesne University
- Language Rehab and Cognition Lab, Department of Communication Sciences and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh
- Lehigh Valley Hospital-Cedar Crest
- Penn Medicine Rehabilitation
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Pennsylvania?
- Yes. We're currently tracking 54 recruiting stroke studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.