Thyroid Surgery clinical trials

Nerve blocks for thyroid surgery to reduce stress response

This study tests whether a special numbing technique (nerve block) given during thyroid removal surgery can reduce your body's stress response and help you recover better. Researchers will measure how well this approach works compared to standard care.

Sore throat after neck surgery study

This study tests if a special spray can help prevent or reduce sore throat after thyroid or parathyroid surgery. It may help you feel more comfortable after your operation.

NTP safety in thyroid surgery: preventing complications

This trial is testing if a technology called NTP (a type of low-temperature plasma) can help prevent complications and improve cancer control when they remove all or part of the thyroid gland. It's for adults having thyroid surgery.

Web and video support during thyroid surgery planning

This study tests a pre-surgery video support program and a secure website to help people prepare for thyroid surgery. It may improve understanding and follow-through by collecting your answers before the operation.

RET inhibitor before surgery for advanced thyroid cancer with RET changes

This trial tests a targeted drug (a RET inhibitor) taken before surgery to help shrink thyroid cancer that has a specific genetic change (RET alteration). It may make surgery easier or more successful.

Imaging removed tissue during cancer surgery

This study tests a high-resolution PET-CT scanner that takes pictures of tissue removed during surgery to help doctors see if all the cancer has been removed. You might qualify if you are having surgery for a range of cancers including breast, prostate, thyroid, skin, gastrointestinal, or brain tumors.

Nerve monitoring during thyroid surgery to protect your voice

This study tests a device that monitors a nerve near your voice box during thyroid surgery. The goal is to help protect your voice by giving the surgeon live feedback on the nerve's location and function.

Pain relief study: nalbuphine added to numbing medicine for thyroid surgery

This study tests if adding nalbuphine to the numbing medicine (bupivacaine) given as a nerve block before thyroid surgery provides better pain relief. It is for adults having planned thyroid surgery.

Dye test to check parathyroid blood flow during thyroid surgery

This trial tests a dye called indocyanine green (ICG) to see how well it shows blood flow to the tiny parathyroid glands during thyroid surgery. This may help doctors know right away if the glands are healthy, which could lower the chance of complications.

Preventing low parathyroid after thyroid surgery

This study aims to find ways to detect and prevent low parathyroid function after thyroid surgery. If you are having your whole thyroid removed, joining could help researchers learn how to improve recovery.

Robotic vs. open surgery for thyroid cancer that has spread

This study compares a robotic surgery method using small incisions under the armpit with standard open surgery for papillary thyroid cancer that has spread to lymph nodes on one side of the neck. It aims to see which approach is better for removing cancer and recovery.

PET scan guided surgery for medullary thyroid cancer

This trial uses a special PET scan to help guide surgery for medullary thyroid cancer (MTC). The goal is to see if this scan can make surgery more precise.

Pain after robotic, endoscopic or open neck surgery for thyroid cancer

This trial compares pain levels after three different surgical methods for removing cancerous lymph nodes in the neck. It may help patients with thyroid cancer that has spread to neck lymph nodes understand which approach causes less discomfort.

Shortwave Infrared Surgical Imaging Device Study

New scar-free thyroid surgery vs. standard surgery for thyroid cancer

This trial compares a new, scar-free surgery (done through a small cut near the collarbone) to the standard open surgery for people with a common type of thyroid cancer. It may be a good option if your cancer is small and hasn't spread.

FAPI-guided surgery for newly diagnosed medullary thyroid cancer

This trial tests whether a special imaging agent (FAPI) can help surgeons remove medullary thyroid cancer more precisely during your first surgery. It is for people who have not yet been treated and are scheduled for surgery within 30 days.

Comparing microwave ablation vs. surgery for low-risk thyroid cancer

This study compares a less invasive procedure (microwave ablation) with traditional surgery for treating a small, low-risk papillary thyroid cancer. If you have a single, small tumor with certain low-risk gene changes, you might be able to avoid surgery and have a quicker recovery.

Better predicting easy thyroid removal through mouth or under chin

This study compares two approaches for thyroid removal surgery—one through the mouth and one under the chin—to find which is easier to perform. It is for people with thyroid nodules or early thyroid cancer that hasn't spread.

Predicting difficult thyroid surgery for less scarring

This trial looks at a tool doctors can use to predict if a certain type of thyroid surgery (through the mouth or under the chin) will be challenging. It helps people who want less visible scarring after their thyroid cancer surgery.

Assessing skills for robotic thyroid surgery

This trial is for people having robotic thyroid surgery (removing all or part of the thyroid with a robot). It aims to create a scoring system to measure how well surgeons perform the procedure. You may be eligible if you have a small thyroid cancer or a benign nodule and want the best cosmetic result.

Pre-surgery treatment for advanced thyroid cancer

This study tests whether giving treatment before surgery (neoadjuvant therapy) helps people with locally advanced thyroid cancer. It aims to shrink the tumor so surgery can be more successful.