Clinical trials
Type 1 diabetes clinical trials
An autoimmune condition where the body makes little or no insulin. We’re tracking 862 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05498974Recruiting
Type 1 diabetes study for people with insulin dependence
This study is looking for people with type 1 diabetes to better understand the condition and how it may be managed. You might qualify if you were diagnosed by a specialist and are insulin-dependent under certain conditions.
Lanzhou, GansuAges Any age - NCT05478707RecruitingPhase 2
Treating small blood vessel problems in type 1 diabetes
This study tests whether two different treatment strategies can improve the function of the tiny blood vessels in people with type 1 diabetes. It aims to find a way to prevent or reduce diabetes-related complications.
Orlando, FloridaAges 18–40 - NCT05414409RecruitingPhase 2
Gut microbiome study in young people with type 1 diabetes
This Phase 2 study looks at the gut microbiome (the bacteria in your intestines) in youth with type 1 diabetes, and how metformin may work differently through the gut. It may help researchers understand mechanisms and future treatment options.
Indianapolis, IndianaAges 11–18 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT03369821Recruiting
Study of immune changes in very early childhood type 1 diabetes
This study looks at immune system cells and gene activity in infants and young children to understand what causes type 1 diabetes to start so early. It may help researchers find earlier warning signs and better ways to support families right at diagnosis.
Seattle, WashingtonAges Up to 70 years - NCT05317455RecruitingEarly Phase 1
Studying brain sugar changes in adults with risky low blood sugar
This early-stage study looks at how the brain uses sugar in people with type 1 diabetes who have had severe or hard-to-notice low blood sugar. It may help researchers understand the brain effects of low blood sugar and guide safer care.
New Haven, ConnecticutAges 18–55 - NCT05139784Recruiting
Study of immune changes in people with type 1 diabetes and other diabetes
This study looks at immune (defense system) and blood-sugar changes in people with type 1 diabetes, and in some other diabetes or autoimmune hormone conditions. It includes people who will have a specific abdominal surgery so doctors can safely study lymph node tissue.
Bobigny, Île-de-France RegionAges 1 year+ - NCT05188014Recruiting
Exercise timing your menstrual cycle in type 1 diabetes
This study looks at how doing exercise at different points in your menstrual cycle affects blood sugar control in people with type 1 diabetes. It may help you and your care team understand how to plan exercise more safely and effectively around your period.
Edmonton, AlbertaAges 18–50 - NCT05153070RecruitingPhase 2
Cyclosporine then low-dose immune therapy for new type 1 diabetes
This Phase 2 study tests whether starting with cyclosporine and then giving low-dose IL-2 can better protect the body’s insulin-producing function after type 1 diabetes is diagnosed. It’s meant for people diagnosed very recently who have specific diabetes-related immune markers.
ParisAges 16–45 - NCT05188027Recruiting
Exercise types for postmenopausal women with type 1 diabetes
This study compares aerobic exercise (like brisk walking) versus resistance exercise (like strength training) to see which works better for women with type 1 diabetes after menopause. It may help you learn which exercise approach is safest and most helpful for blood sugar and health.
Edmonton, AlbertaAges 45–75 - NCT05055804Enrolling by invitation
Study links an ELG test reading to blood glucose
This study looks at whether a new ELG test reading matches your blood sugar results in people with type 1 or type 2 diabetes. You may be asked to fast and come for two short visits so researchers can compare the tests.
Springdale, ArkansasAges 25–65 - NCT04933851RecruitingPhase 2
Support for emotional distress in adults with type 1 diabetes
This study tests an emotional support program to help people with type 1 diabetes who feel significant diabetes-related distress. It may improve how you cope and support better diabetes outcomes.
San Diego, CaliforniaAges 18 years+ - NCT04963777Recruiting
Prebiotics for gut health in young people with type 1 diabetes
This trial studies whether taking prebiotics can change gut bacteria (gut microbiome) in people with type 1 diabetes. The goal is to see if these gut changes are linked to better health or diabetes-related outcomes.
Calgary, AlbertaAges 7 years+ - NCT04786262RecruitingPhase 3
A study of VX-880 and VX-017 for type 1 diabetes
This study tests two investigational drugs, VX-880 and VX-017, for people with type 1 diabetes who have trouble controlling their blood sugar and have frequent severe low blood sugar episodes. The goal is to see if these drugs can improve blood sugar control and reduce dangerous lows.
Duarte, CaliforniaAges 18–65 - NCT04477928Recruiting
Checking type 1 diabetes risk using routine child care
This study estimates the chance of developing type 1 diabetes in children by using information gathered during regular well-child visits. It may help identify children who could benefit from earlier monitoring.
Bemidji, MinnesotaAges birth–17 years - NCT03648918Recruiting
Study family genetics in type 1 diabetes
This study looks at genetic patterns in families where someone has type 1 diabetes (an autoimmune condition). It may help researchers understand why type 1 diabetes happens and who is at risk.
Milwaukee, WisconsinAges 2 years+ - NCT03585153Enrolling by invitation
Pancreas imaging study in people with type 1 diabetes
This study takes pictures of the pancreas in children and teens (and likely adults) with type 1 diabetes soon after diagnosis. The goal is to learn more about how the pancreas changes with diabetes, which may help future care.
Aurora, ColoradoAges 8 years+ - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
San Francisco, CaliforniaAges 8–35 - NCT01779115Enrolling by invitation
Diabetes registry for people with diagnosed high blood sugar
This is a research registry that collects information from people who have diabetes (high blood sugar on tests or based on diabetes treatment). It may help researchers understand diabetes patterns in a real-world healthcare system.
Tel AvivAges Any age - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT07568678RecruitingPhase 1
Testing HMS1005 in adults with type 2 diabetes
This study tests a new medicine called HMS1005 in people with type 2 diabetes. Researchers want to see how safe it is and how the body responds to different doses. You may qualify if you have type 2 diabetes that is either untreated or controlled with common diabetes medications.
Miami, FloridaAges 18–65 - NCT07394114RecruitingPhase 3
Study of a new medicine for type 2 diabetes not controlled by diet and exercise
This trial tests a new medicine called HDM1005 for people with type 2 diabetes who haven't been helped enough by diet and exercise alone, and who haven't taken any diabetes medication in the last 12 weeks. It aims to see if the medicine can help lower blood sugar levels safely.
BeijingAges 18–75 - NCT07373938Recruiting
Carotid Artery Texture and Heart Risk in Type 2 Diabetes
This study uses a neck ultrasound to look at the texture of your carotid artery (a main blood vessel in your neck) to find early signs of heart and blood vessel risk. It is for adults with type 2 diabetes who have not already had a heart attack or stroke.
Elche, AlicanteAges 40–69 - NCT07319286Enrolling by invitationPhase 1/Phase 2
GLP-1 drug for period problems in teens with type 1 diabetes
This trial tests whether a GLP-1 receptor agonist can help improve irregular periods in teenage girls with type 1 diabetes. It's for girls aged 12 to 18 who have had their period for at least 2 years, use a continuous glucose monitor, and have higher blood sugar levels (HbA1c of 7% or more).
Cairo, Cairo GovernorateAges 12–18
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Common questions
- Are there clinical trials for type 1 diabetes?
- Yes. Clin2 currently lists 862 recruiting type 1 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 1 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.