Clinical trials
Vagus Nerve Stimulation clinical trials
Below are recruiting vagus nerve stimulation clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07711353Recruiting
Nerve stimulation plus physical therapy for frozen shoulder
This trial tests whether adding a gentle nerve stimulation device to standard physical therapy helps people with frozen shoulder (adhesive capsulitis) recover better. The stimulation is applied to the ear and is designed to be safe and non-invasive.
Istanbul, IstanbulAges 18–65 - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT07629687Recruiting
Ear Nerve Stimulation for Balance After Stroke
This trial tests a non-invasive device that stimulates a nerve in your ear to help improve balance and body control after stroke. It may help you regain stability and reduce symptoms like muscle tightness.
Islamabad, Punjab ProvinceAges 18–70 - NCT07719595Recruiting
Vagus nerve stimulation for coma after brain injury
This trial tests if a gentle electrical stimulation of the vagus nerve (a nerve in the neck) can help people regain consciousness after a severe traumatic brain injury. It is for patients who are in a coma or minimally conscious state, and the treatment is given along with standard ICU care.
Stony Brook, New YorkAges 18 years+ - NCT04534556Enrolling by invitation
Wireless nerve stimulation to improve stroke recovery
This study tests a wireless nerve stimulation device placed near the vagus nerve to help people recover after a stroke. It focuses on people with specific remaining arm/hand movement and recovery levels at least 12 months after stroke.
Dallas, TexasAges 22–79 - NCT04557618Recruiting
Ear nerve stimulation after a brain bleed
This trial studies whether stimulating a nerve near the ear (auricular VNS) can help after a spontaneous subarachnoid hemorrhage, a type of bleeding around the brain. If you qualify, you may receive the ear stimulation as an added treatment while doctors monitor your recovery.
St Louis, MissouriAges 18 years+ - NCT04415203Recruiting
Treatment for frequent extra heartbeats using a simple patch
This trial tests a non-surgery treatment (using a skin patch) for people who have frequent extra heartbeats coming from the heart’s lower chambers. It’s meant to see whether the patch reduces symptoms or abnormal heart rhythm compared with usual care.
Beijing, Beijing MunicipalityAges 18–75 - NCT04177511Recruiting
Vagus nerve ear stimulation for endometriosis pelvic pain
This trial tests whether stimulating a nerve through the ear (non-surgical, through the skin) can reduce chronic pelvic pain from endometriosis. It may help if standard care hasn’t fully controlled symptoms like painful periods or pain during sex.
Suresnes, Île-de-France RegionAges 15 years+ - NCT04100486Enrolling by invitation
Testing a noninvasive device to measure your body signals
This study uses a noninvasive bioelectronic device to record your body’s automatic (involuntary) signals. The goal is to see how well the device can analyze these signals and how your body responds in a controlled setting.
Manhasset, New YorkAges 18–60 - NCT04099992Recruiting
Mindfulness program for people with chronic kidney disease
This trial tests whether a mindfulness-based program can help people living with moderate-to-advanced kidney disease. It may improve how you feel day-to-day and how you manage symptoms, while researchers track kidney-related health and safety.
Atlanta, GeorgiaAges 40–80 - NCT07619989Recruiting
Ear nerve stimulation for weight loss after tirzepatide
This trial tests if a gentle electrical stimulation to the ear can help people who haven't lost much weight with tirzepatide (a diabetes/weight drug). It's for people who are still overweight after 12 weeks of treatment.
Nanjing, JiangsuAges 18–50 - NCT07761507Recruiting
Ear stimulation to help wake up after brain bleed surgery
This trial tests a gentle ear stimulation device that may help people regain consciousness after surgery for a brain bleed. It is done while the person is in the hospital and may improve recovery.
BeijingAges 18–75 - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT07600424Recruiting
Ear Stimulation Device for Moderate to Severe Facial Redness
This trial tests a small device worn on your ear that sends gentle electrical signals to a nerve, aiming to reduce facial redness and flushing from rosacea. The device may help calm the inflammation that causes rosacea symptoms.
Boston, MassachusettsAges 18 years+ - NCT07549243Recruiting
Ear Nerve Stimulation to Protect Kidneys During Heart Surgery
This trial tests whether gentle electrical stimulation applied to your ear can help protect your kidneys during heart surgery that uses a heart-lung machine. Kidney damage after this type of surgery is common, and researchers want to see if this non-invasive stimulation can prevent it.
Hangzhou, ZhejiangAges 18 years+ - NCT07822932Recruiting
Ear nerve stimulation for HIV-related nerve pain
This study tests a gentle ear stimulation device that may ease tingling, burning, or numbness from HIV-related nerve damage in the hands and feet. It could offer a drug-free way to manage nerve pain.
Miami, FloridaAges 50 years+ - NCT07487818RecruitingPhase 2/Phase 3
Vagus nerve stimulation with nicotine replacement for quitting smoking
This study tests whether adding a gentle nerve stimulation device to nicotine replacement therapy (like patches or gum) can help people quit smoking more effectively. It may be a new option for those who have struggled to quit before.
Rochester, MinnesotaAges 18 years+ - NCT07574580Enrolling by invitation
Vagus Nerve Stimulation for Acute Burn Injury Recovery
This trial tests a non-invasive device that stimulates the vagus nerve (a major nerve in your body) through your ear to help reduce inflammation and pain after severe burns. The goal is to see if this can speed healing and improve recovery in patients with moderate to severe burn injuries.
Istanbul, KartalAges 18–65 - NCT07486804Recruiting
Brain stimulation to help teens who self-injure
This study tests if a gentle, non-invasive brain stimulation technique (like wearing a special cap) can help teenagers who hurt themselves on purpose. It compares two types of stimulation to see which one reduces the urge to self-injure.
Hefei, AnhuiAges 12–22 - NCT07719387Enrolling by invitation
Vagus nerve stimulation to boost thinking and learning after stroke
This study tests if vagus nerve stimulation, delivered through an implanted device, can help improve thinking and learning in people who have had a stroke. You would use the device at home for six weeks.
Stony Brook, New YorkAges 22 years+ - NCT07636304Enrolling by invitationEarly Phase 1
Brain stimulation for inflammatory bowel disease remission
This study tests whether a non-invasive device that stimulates the vagus nerve (a major nerve in your neck) can affect brain function in people whose IBD is in remission. Researchers want to understand if this stimulation might help reduce inflammation or improve symptoms in the future.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT07566923Enrolling by invitation
Vagus Nerve Stimulation for Teen Burn Recovery
This study tests a non-invasive device placed on the ear that stimulates the vagus nerve (a major nerve that affects stress and healing) to help adolescents recovering from burns feel less anxious, sleep better, and experience less pain and itching. The device is worn on the outside of the ear and may help your body heal.
Istanbul, KartalAges 12–18 - NCT07566910Enrolling by invitation
Vagus Nerve Stimulation to Reduce Pain During Burn Dressing Changes
This study tests a non-invasive device that stimulates a nerve in your ear to help reduce pain and stress during burn wound dressing changes. The device is applied to the outer ear and may help your body manage pain naturally without extra medication.
Istanbul, KartalAges 18–65 - NCT07566871Enrolling by invitation
Nerve Stimulation to Help Burn Injury Recovery
This study tests whether gentle electrical stimulation of a nerve in your ear can help reduce anxiety, improve sleep, and ease pain or itching after a burn injury heals. You would wear a small device on your ear for several weeks.
Istanbul, KartalAges 18–65
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Common questions
- Are there clinical trials for vagus nerve stimulation?
- Yes. Clin2 currently lists 155 recruiting vagus nerve stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vagus nerve stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vagus nerve stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.