Clinical trials
Vagus Nerve Stimulation clinical trials
Below are recruiting vagus nerve stimulation clinical trials, each written for real people, not researchers. We’re tracking 158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06817161RecruitingPhase 3
Nerve stimulation for quality of life during ovarian cancer treatment
This trial tests if a gentle nerve stimulation device on the ear can improve quality of life for people with ovarian cancer who are starting their first chemotherapy. It may help manage symptoms like fatigue or feeling sick.
CaenAges 18 years+ - NCT06827301Recruiting
Vagus nerve stimulation for swallowing problems after stroke
This trial tests a non-invasive device that stimulates a nerve in the ear to help improve swallowing after a recent stroke. It may be an option if you have moderate swallowing difficulties diagnosed within the first week after your stroke.
Roma, RMAges 18 years+ - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT06912334Recruiting
Vagus nerve stimulation for fibromyalgia pain relief
This trial tests a device that uses gentle electrical pulses on the ear to stimulate the vagus nerve, which may help reduce fibromyalgia pain and sensitivity. You will not know if you are receiving the real stimulation or a placebo to ensure unbiased results.
Athens, GreeceAges 18–79 - NCT06923007Recruiting
Vagus nerve stimulation for Alzheimer's disease
This trial tests if a nerve stimulation device can help people with mild to moderate Alzheimer's. It is for patients aged 50 to 80 who are on a stable medication.
BeijingAges 50–80 - NCT06930716Recruiting
Vagus nerve stimulation with physical therapy for consciousness disorders
This trial tests whether a mild electrical stimulation of the vagus nerve (a nerve in the neck) can help people with long-term disorders of consciousness move better during physical therapy. It may be an option if you are still in a coma, vegetative, or minimally conscious state and have been stable for more than 6 weeks.
New York, New YorkAges 22 years+ - NCT06938243RecruitingPhase 1
Vagus Nerve Stimulation for Early Stroke Arm Recovery
This trial tests whether a device called a vagus nerve stimulator (VNS), placed under the skin, is safe and helps improve arm function when started 3 months after a stroke. It is for people with moderate to severe arm weakness who can still move their arm a little.
Jinan, ShandongAges 30–75 - NCT06957912Recruiting
Ear nerve stimulation for recovery after major surgery
This trial tests if stimulating a nerve in your ear (vagus nerve) before and after noncardiac surgery can improve your recovery. It's for adults aged 18 to 84 having planned or time-sensitive surgery lasting at least 2 hours.
Beijing, Beijing MunicipalityAges 18–85 - NCT07000175Recruiting
Heart rate measurement on arm vs. chest during nerve stimulation
This study compares two ways of measuring heart rate variability (a sign of how well your nervous system is working) during a gentle nerve stimulation therapy. It looks for healthy volunteers to see if a simple arm measurement works as well as a chest measurement.
Trabzon, OrtahisarAges 18–45 - NCT07007884Recruiting
Ear stimulation to improve heart function after spinal cord injury
This trial uses mild electrical stimulation through the ear to see if it can improve how the heart works in people who have had a spinal cord injury. It is designed for individuals with neck-level injuries who also experience episodes of sudden high blood pressure (autonomic dysreflexia).
AnkaraAges 18–60 - NCT07017686Recruiting
Reboot Study: Nerve stimulation for rheumatoid arthritis
This study tests a device that sends mild electrical pulses to the vagus nerve in the abdomen to treat rheumatoid arthritis. It is for people whose arthritis has not improved after trying multiple medications.
Fitzroy, VictoriaAges 18–75 - NCT07022171Recruiting
Ear stimulation for depression
This study tests if a gentle electrical device worn on the ear can help improve depression symptoms. It uses a non-invasive method to stimulate the vagus nerve, which may affect mood.
MunichAges 18–65 - NCT07055373Recruiting
Nerve stimulation for chronic whiplash pain
This trial tests if a gentle nerve stimulation device on the ear can reduce neck pain and disability in people with long-term whiplash symptoms. It aims to find a safe, non-drug option for pain relief.
Calgary, AlbertaAges 18–65 - NCT07081568Recruiting
Vagus nerve stimulation for stroke recovery
This trial tests a device that uses gentle stimulation on your ear to help your brain recover movement and feeling after a stroke. It is for people who had their first ischemic stroke within the last two weeks.
Nanchang, JiangxiAges 18–80 - NCT07118956Recruiting
Ear stimulation for apathy in Parkinson's
This trial tests whether a gentle electrical stimulation on your ear (taVNS) can help improve low motivation (apathy) in people with Parkinson's. It also uses MRI scans to see how the treatment affects the brain.
Hefei, AnhuiAges 40–90 - NCT07123987Recruiting
Ear nerve stimulation for post-shingles pain
This study tests a gentle, non-invasive device that stimulates a nerve in your ear to see if it can reduce lingering pain after shingles. It may be a good option if you have had persistent nerve pain for at least 3 months.
Cairo, Giza GovernorateAges 35–65 - NCT07198100Recruiting
Ear stimulation, motivation, and insulin sensitivity in depression
This study explores how a gentle electrical stimulation of the ear might affect mood, motivation, and insulin sensitivity in people with and without depression. It aims to see if this non-invasive technique could offer new ways to help with depression.
BonnAges 18–60 - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT07219108Recruiting
Vagus nerve stimulation for recovery in the NeuroICU
This trial tests whether a gentle electrical pulse on the ear can help patients recover from severe brain or spinal cord conditions in the NeuroICU. It may improve healing by activating the vagus nerve.
St Louis, MissouriAges 18 years+ - NCT07682090Recruiting
Nerve stimulation for fibromyalgia pain
This study tests a gentle nerve stimulation device worn near your ear to see if it can reduce fibromyalgia pain and improve how your body handles stress. It is a non-invasive treatment option that you receive while continuing your regular medications.
Rome, LazioAges 18–70 - NCT07681336Recruiting
Ear nerve stimulation for chronic low back pain
This trial tests if stimulating the vagus nerve through the ear can reduce chronic low back pain in people who haven't gotten enough relief from painkillers. It aims to see if this non-invasive treatment can help manage pain without medication.
Ghent, Oost-VlaanderenAges 30–60 - NCT07253870Recruiting
Nerve stimulation for subacute stroke recovery
This study compares two types of nerve stimulation (one on the ear, one on the neck) to see which helps upper limb movement better in people who had a stroke 3–6 months ago. It may help improve arm and hand function.
Lahore, Punjab ProvinceAges 45–70 - NCT07283913Recruiting
Non-invasive ear nerve stimulation for healthy volunteers
This study tests whether a non-invasive device that stimulates a nerve in the ear can affect health. It is for healthy adults who are not taking medications (except birth control) and can avoid eating and exercise for 12 hours before two of the visits.
Nottingham, NottinghamshireAges 18 years+ - NCT07284732Recruiting
Ear nerve stimulation for consciousness disorders
This trial tests whether a gentle electrical stimulation on the ear can help people with disorders of consciousness, like a vegetative or minimally conscious state. It aims to see if this noninvasive treatment can improve brain function and awareness.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for vagus nerve stimulation?
- Yes. Clin2 currently lists 158 recruiting vagus nerve stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vagus nerve stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vagus nerve stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.