Clinical trials
Vagus Nerve Stimulation clinical trials
Below are recruiting vagus nerve stimulation clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07219108Recruiting
Ear stimulation to help recovery in the neuro ICU
This study tests a gentle device that stimulates a nerve in the ear to see if it helps patients in the neuroscience intensive care unit recover from serious brain or spinal cord conditions. It might reduce complications and improve recovery.
St Louis, MissouriAges 18 years+ - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT06303960RecruitingEarly Phase 1
Brain stimulation for chronic stroke arm recovery
This early-phase trial tests whether brain stimulation (deep brain stimulation in the cerebellum or vagus nerve stimulation) can help improve arm and hand movement in people who had a stroke 1 to 3 years ago.
Jinan, ShandongAges 30–75 - NCT06938243RecruitingPhase 1
Vagus Nerve Stimulation for Early Stroke Arm Recovery
This trial tests whether a device called a vagus nerve stimulator (VNS), placed under the skin, is safe and helps improve arm function when started 3 months after a stroke. It is for people with moderate to severe arm weakness who can still move their arm a little.
Jinan, ShandongAges 30–75 - NCT07198100Recruiting
Ear stimulation, motivation, and insulin sensitivity in depression
This study explores how a gentle electrical stimulation of the ear might affect mood, motivation, and insulin sensitivity in people with and without depression. It aims to see if this non-invasive technique could offer new ways to help with depression.
BonnAges 18–60 - NCT06421077Recruiting
Ear nerve stimulation to prevent confusion after surgery in older adults
This trial tests if a gentle electrical stimulation on the ear can help prevent postoperative delirium (sudden confusion) in older patients after surgery. It focuses on people 65 and older who will have longer operations.
BeijingAges 65 years+ - NCT07118956Recruiting
Ear stimulation for apathy in Parkinson's
This trial tests whether a gentle electrical stimulation on your ear (taVNS) can help improve low motivation (apathy) in people with Parkinson's. It also uses MRI scans to see how the treatment affects the brain.
Hefei, AnhuiAges 40–90 - NCT07123987Recruiting
Ear nerve stimulation for post-shingles pain
This study tests a gentle, non-invasive device that stimulates a nerve in your ear to see if it can reduce lingering pain after shingles. It may be a good option if you have had persistent nerve pain for at least 3 months.
Cairo, Giza GovernorateAges 35–65 - NCT07081568Recruiting
Vagus nerve stimulation for stroke recovery
This trial tests a device that uses gentle stimulation on your ear to help your brain recover movement and feeling after a stroke. It is for people who had their first ischemic stroke within the last two weeks.
Nanchang, JiangxiAges 18–80 - NCT07055373Recruiting
Nerve stimulation for chronic whiplash pain
This trial tests if a gentle nerve stimulation device on the ear can reduce neck pain and disability in people with long-term whiplash symptoms. It aims to find a safe, non-drug option for pain relief.
Calgary, AlbertaAges 18–65 - NCT07017686Recruiting
Reboot Study: Nerve stimulation for rheumatoid arthritis
This study tests a device that sends mild electrical pulses to the vagus nerve in the abdomen to treat rheumatoid arthritis. It is for people whose arthritis has not improved after trying multiple medications.
Fitzroy, VictoriaAges 18–75 - NCT07022171Recruiting
Ear stimulation for depression
This study tests if a gentle electrical device worn on the ear can help improve depression symptoms. It uses a non-invasive method to stimulate the vagus nerve, which may affect mood.
MunichAges 18–65 - NCT07007884Recruiting
Ear stimulation to improve heart function after spinal cord injury
This trial uses mild electrical stimulation through the ear to see if it can improve how the heart works in people who have had a spinal cord injury. It is designed for individuals with neck-level injuries who also experience episodes of sudden high blood pressure (autonomic dysreflexia).
AnkaraAges 18–60 - NCT06957912Recruiting
Ear nerve stimulation for recovery after major surgery
This trial tests if stimulating a nerve in your ear (vagus nerve) before and after noncardiac surgery can improve your recovery. It's for adults aged 18 to 84 having planned or time-sensitive surgery lasting at least 2 hours.
Beijing, Beijing MunicipalityAges 18–85 - NCT07000175Recruiting
Heart rate measurement on arm vs. chest during nerve stimulation
This study compares two ways of measuring heart rate variability (a sign of how well your nervous system is working) during a gentle nerve stimulation therapy. It looks for healthy volunteers to see if a simple arm measurement works as well as a chest measurement.
Trabzon, OrtahisarAges 18–45 - NCT06987565RecruitingPhase 2
Nerve stimulation device for lupus pain
This trial tests whether a non-invasive nerve stimulation device worn on the ear can help reduce pain and inflammation in people with lupus. It may be an option if you have moderate to severe muscle or joint pain and are not on certain medications that were recently started.
Manhasset, New YorkAges 18 years+ - NCT06923007Recruiting
Vagus nerve stimulation for Alzheimer's disease
This trial tests if a nerve stimulation device can help people with mild to moderate Alzheimer's. It is for patients aged 50 to 80 who are on a stable medication.
BeijingAges 50–80 - NCT06954844Enrolling by invitation
Study of ear stimulation for weight-related health in young adults
This study tests whether a gentle electrical stimulation of the ear (tVNS) can affect how the body handles weight. It aims to understand the brain and body changes related to obesity. Participants will receive the stimulation and undergo brain scans.
BonnAges 18–40 - NCT06930716Recruiting
Vagus nerve stimulation with physical therapy for consciousness disorders
This trial tests whether a mild electrical stimulation of the vagus nerve (a nerve in the neck) can help people with long-term disorders of consciousness move better during physical therapy. It may be an option if you are still in a coma, vegetative, or minimally conscious state and have been stable for more than 6 weeks.
New York, New YorkAges 22 years+ - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT06817161RecruitingPhase 3
Nerve stimulation for quality of life during ovarian cancer treatment
This trial tests if a gentle nerve stimulation device on the ear can improve quality of life for people with ovarian cancer who are starting their first chemotherapy. It may help manage symptoms like fatigue or feeling sick.
CaenAges 18 years+ - NCT06793800Recruiting
Ear nerve stimulation to improve breathing after stroke
This study tests whether a gentle nerve stimulation device placed on your ear can improve your breathing after a stroke. It's for people who had a first stroke 1 to 3 years ago and are otherwise generally healthy (no heart, lung, or ear problems).
IstanbulAges 40–80 - NCT06799390Recruiting
Ear stimulation after brain bleed
This study tests whether gentle electrical stimulation through the ear (called auricular VNS) can help people recover after a bleed in the upper part of the brain. It aims to reduce inflammation and improve outcomes when started within 48 hours.
St Louis, MissouriAges 18 years+ - NCT04415203Recruiting
Treatment for frequent extra heartbeats using a simple patch
This trial tests a non-surgery treatment (using a skin patch) for people who have frequent extra heartbeats coming from the heart’s lower chambers. It’s meant to see whether the patch reduces symptoms or abnormal heart rhythm compared with usual care.
Beijing, Beijing MunicipalityAges 18–75
Hear when a new Vagus Nerve Stimulation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for vagus nerve stimulation?
- Yes. Clin2 currently lists 155 recruiting vagus nerve stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vagus nerve stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vagus nerve stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.