Clinical trials
Ventilation clinical trials
Below are recruiting ventilation clinical trials, each written for real people, not researchers. We’re tracking 523 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05741697Recruiting
High-flow oxygen for bronchiectasis flare-ups in intensive care
This trial tests high-flow oxygen (a special oxygen delivery through a device) for people hospitalized with a bronchiectasis flare-up who need breathing support. It may help people avoid more invasive breathing machines and improve comfort and breathing during a severe episode.
Asyut, Asyut GovernorateAges 18–80 - NCT05767671Recruiting
Breathing tube patients in ICU tested for lung inflammation treatment
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Denver, ColoradoAges 18–99 - NCT05785637Recruiting
Home sleep testing after starting noninvasive breathing support
This study checks breathing/sleep measurements done at home for people who recently started a machine that helps them breathe without an endotracheal tube. It may help the team confirm how well home monitoring works after hospital setup of this breathing support.
GarchesAges 18 years+ - NCT05866835Recruiting
Digital mouth guard safety and fit check in boxing or rugby
This study tests a digitalised way of providing or checking an intraoral (mouth) protection device for people who play contact sports like boxing, rugby, or football. It mainly checks whether the protection can be safely used for eligible participants.
BordeauxAges 16–35 - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05881031Recruiting
Home breathing support for medically complex children
This trial studies whether starting a noninvasive breathing machine (given without a tube in the airway) at home works well and is tolerated in children with medical complexity. It may help improve comfort and safety when new breathing support is prescribed.
Toronto, OntarioAges 5 years–17.9 years - NCT05920109Recruiting
Early pain block to help breathing after severe chest trauma
This study tests whether an early pain-numbing injection to the chest wall can reduce how much ventilator support (breathing machine) people need after severe blunt chest injury with multiple rib fractures. If it works, it may help patients breathe more easily and spend less time on ventilation in the ICU.
BordeauxAges 18 years+ - NCT05928052Recruiting
Spinal stimulation to help ARDS patients get off the ventilator
This study tests whether stimulating nerves in the spine can help people with severe lung injury (ARDS) breathe without a ventilator sooner. It may help shorten the time you need a breathing machine in the ICU.
Los Angeles, CaliforniaAges 18 years+ - NCT05952648Recruiting
Test for pneumonia in ICU using fast DNA testing
This study checks whether a fast “DNA test” can help diagnose hospital-acquired or ventilator-associated pneumonia in very sick patients with sepsis. If the test is accurate, it may help doctors start the right treatment sooner.
BolognaAges 18 years+ - NCT05979545RecruitingPhase 4
Early treatment with ceftazidime-avibactam for serious infections
This study tests an antibiotic called ceftazidime-avibactam for people with serious infections like bloodstream infections or pneumonia that started in the hospital or from a breathing machine. It aims to start treatment quickly after identifying the bacteria.
Kuala LumpurAges Any age - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT05990348Recruiting
Comparing two breathing support methods for weaning from ventilator
This study compares two ways of helping patients breathe on a ventilator after a failed attempt to come off the machine. It looks at how the diaphragm and rib muscles work during each method to find the best approach for weaning.
RomeAges 18 years+ - NCT06000761Recruiting
Mouth care with human milk for premature babies
This trial is testing whether giving gentle mouth care with human milk to very premature babies in the NICU can help their health. It focuses on babies born early and with low birth weight whose mothers can provide milk.
Gainesville, FloridaAges 1 hour–3 days - NCT06009731Recruiting
Diaphragm ultrasound during breathing trial
This study uses a special ultrasound technique to look at how your diaphragm (the main breathing muscle) moves while you try breathing on your own. It may help doctors better understand when patients are ready to come off the breathing machine.
AmiensAges 18 years+ - NCT06014138RecruitingPhase 2/Phase 3
Volatile sedation study for ARDS patients
This trial is comparing a new type of inhaled sedative (volatile sedation) to usual IV sedatives for people with ARDS who are on a ventilator in the ICU. It aims to see if it can help patients breathe better and recover more quickly.
London, LondonAges 17 years+ - NCT06021938Recruiting
Virtual Reality for Breathlessness in ALS
This trial tests if using immersive virtual reality can help reduce ongoing shortness of breath in people with ALS who already use a breathing mask (non-invasive ventilation). It may offer a drug-free way to feel more comfortable.
Paris, FranceAges 18 years+ - NCT06026163RecruitingPhase 2/Phase 3
Caffeine for breathing help in late preterm babies
This trial tests if giving caffeine to late preterm babies with breathing problems helps them need less breathing support. It could be an extra treatment alongside standard care.
Madinah, Medina RegionAges 1 day–3 days - NCT06030349Recruiting
Breathing support for kids with Down syndrome and sleep apnea
This trial looks at how well non-invasive breathing machines help children with Down syndrome who have obstructive sleep apnea. It tracks their health and sleep over time to see if the treatment works and improves daily life.
DublinAges 6 months–16 years - NCT06035120Recruiting
Sealing damaged lung parts in severe emphysema
This trial tests a new treatment called AeriSeal to seal off damaged parts of the lung in people with severe emphysema. It aims to help you breathe better by reducing the amount of air trapped in your lungs.
Phoenix, ArizonaAges 40–80 - NCT06045429RecruitingPhase 4
Mouth rinse for ICU patients on breathing machines
This trial tests if using a special mouthwash (3% hydrogen peroxide) can reduce bacteria in the lungs of ICU patients on breathing machines. It may help prevent infections in people who are already very sick.
PragueAges 18 years+ - NCT06073834Recruiting
Lung infection study in ICU patients
This trial tests a new way to better understand lung infections in very sick ICU patients. It looks at people with septic shock, severe trauma, or major burns to see if an infection is the cause.
LyonAges 18 years+ - NCT06101511Recruiting
Breathing tube pressure for safer abdominal surgery
This trial is testing if using less air pressure from the breathing machine during abdominal surgery can help prevent lung complications. If you are at higher risk for breathing problems after surgery, this study may help find a safer way to manage your breathing during the operation.
Amsterdam, NoordhollandAges 18–100 - NCT06110403RecruitingPhase 1/Phase 2
Study of a long-acting inhaler for COPD symptoms and lung function
This trial tests a once-daily inhaler that combines a long-acting bronchodilator with a corticosteroid to see if it improves breathing, lung function, and quality of life in people with moderate-to-severe COPD who have significant shortness of breath.
LilleAges 40–75 - NCT06114667Recruiting
Nasal high flow vs. mask for COPD flare-up
This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.
Montpellier, MontepllierAges 18–85
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Common questions
- Are there clinical trials for ventilation?
- Yes. Clin2 currently lists 523 recruiting ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.