Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT04933552Recruiting
Safety study of Mayzent during pregnancy for babies
This study follows pregnant people with multiple sclerosis (MS) who took Mayzent (siponimod) to understand safety for pregnancy outcomes. It compares them with other groups to see whether there are any differences in birth results.
La Jolla, CaliforniaAges Any age - NCT06417710Recruiting
Standardized check-up for leptomeningeal metastasis
This study watches and writes down how patients with cancer that has spread to the brain or spinal cord lining (leptomeningeal metastases) are doing. It helps doctors learn more about this condition without giving any new treatments.
Houston, TexasAges 18 years+ - NCT06417502Recruiting
China pediatric rheumatic disease registry study
This study collects information from children with rheumatic and immune system diseases in China to better understand these conditions. By participating, you help researchers learn more about how to diagnose and treat these diseases.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT06418113RecruitingPhase 1
Radiation and chemo before surgery for glioblastoma
This trial tests giving radiation and chemotherapy before surgery for glioblastoma. It aims to see if this approach is safe and may help improve outcomes for patients whose tumor can be completely removed.
MadridAges 18–75 - NCT04589299RecruitingPhase 4
Subcutaneous immune globulin for newly diagnosed CIDP
This study tests whether giving immune globulin under the skin (SCIG) can help people with newly diagnosed CIDP. It may help improve muscle strength and nerve symptoms while avoiding the need for earlier IVIG/SCIG treatment.
AalborgAges 18 years+ - NCT06215274Recruiting
Leisure activities and early Alzheimer's study
This trial looks at how engaging in mentally stimulating leisure activities (like puzzles, reading, or games) may affect brain health in people with early memory concerns. Researchers want to understand the brain changes that happen with these activities.
Fuzhou, FujianAges 60 years+ - NCT06420310Recruiting
Pesticides and Parkinson's disease study
This study looks at how pesticides might be linked to Parkinson's disease by comparing farmers who have been exposed to pesticides with people who have not been exposed. It aims to help understand what causes the disease.
BurgosAges 45–55 - NCT06370104Recruiting
Online therapy for recent suicidal thoughts or behavior
This study tests a remote therapy program for people who have had suicidal thoughts or behaviors in the past month. It aims to provide timely support without needing to see a therapist in person.
Amsterdam, South HollandAges 16 years+ - NCT07852767Recruiting
Spinal anaesthesia success after previous back surgery
This study looks at how well spinal anaesthesia (a numbing injection in the back) works for people who have had lumbar spine surgery in the past. It aims to see if previous back surgery affects the success of this type of anaesthesia, which could help doctors plan better care.
IstanbulAges 18 years+ - NCT06392815Recruiting
PET scan for Lyme neuroborreliosis diagnosis
This trial tests whether a special PET scan (64Cu-DOTATATE) can help diagnose Lyme neuroborreliosis (LNB), an infection of the nervous system caused by Lyme disease. The study aims to see if this scan can detect the infection earlier or more accurately than current methods.
Copenhagen, Capital RegionAges 18–90 - NCT07851051Recruiting
Memory training and brain changes in healthy young adults
This study looks at how training your working memory (the ability to hold and use information in your mind) affects brain activity. You would undergo MRI scans and do memory exercises to help researchers understand how the brain changes with practice, which may lead to better cognitive training methods.
ParisAges 18–30 - NCT07852156Recruiting
Cooling during inpatient rehabilitation for people with multiple sclerosis
This trial tests whether cooling the body during a stay at a rehabilitation clinic helps people with multiple sclerosis (MS) feel better and recover more effectively. If you have MS and find that heat makes your symptoms worse, this study may help you manage your symptoms during rehab.
Valens, Canton of St. GallenAges 18 years+ - NCT07851363Recruiting
Spinal fluid test for tracking brain lymphoma
This study uses a simple spinal fluid test (liquid biopsy) to find and track how primary CNS lymphoma responds to treatment. The goal is to help doctors plan your care with fewer invasive procedures.
Beijing, Beijing MunicipalityAges 18–75 - NCT07851480Recruiting
Predicting nightmares in military veterans with PTSD
This study is testing whether wearable sensors can predict when a nightmare is about to happen by looking at body signals like heart rate and breathing. If it works, it could lead to earlier help for people with PTSD who suffer from frequent nightmares.
BrestAges 18–65 - NCT07852936Recruiting
Group therapy for emotional recovery after brain injury
This study tests a group-based talk therapy program designed to help people with acquired brain injury express and process emotions, aiming to improve mental health and coping after injury.
UppsalaAges 18 years+ - NCT07851636Recruiting
Fast genetic testing to guide treatment for rare brain tumors
This trial tests a new way to pick treatments for rare brain tumors that have come back. Doctors will quickly analyze your tumor's genes and test drugs in the lab to find the best option for you.
Washington D.C., District of ColumbiaAges Up to 45 years - NCT07852728RecruitingPhase 2
Oxygen therapy for first responders after head injuries
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and overall well-being in first responders who have had a traumatic brain injury and still have symptoms. If you are a first responder dealing with ongoing brain injury symptoms, this study could help you find new ways to feel better.
Boise, IdahoAges 18–75 - NCT07852403Recruiting
Sleep problems and outcomes in pulmonary arterial hypertension
This study looks at how sleep-disordered breathing (abnormal breathing during sleep) affects the long-term health of people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. By participating, you will have a sleep study and be followed over time to see how your breathing during sleep relates to your PAH outcomes.
BeijingAges 18 years+ - NCT05906992RecruitingPhase 3
Testing CT-P53 versus Ocrevus for relapsing MS
This Phase 3 study compares CT-P53 with Ocrevus in people with relapsing-remitting multiple sclerosis (MS). It aims to see how well each treatment controls MS activity and to compare safety and study drug effects.
PoznanAges 18–55 - NCT06426615Recruiting
Understanding brain signals in unresponsive states after injury
This study looks at brain activity in people who are unresponsive after a brain injury. It uses advanced brain scans to see if there are hidden signs of consciousness, which could help doctors better understand and care for these patients.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06428734Recruiting
Outcomes study for normal pressure hydrocephalus
This study follows people with idiopathic normal pressure hydrocephalus (iNPH) to track their health outcomes over time. It helps doctors understand how the condition naturally progresses without surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06371937Recruiting
Heart and blood vessel disease biobank study
This study creates a collection of skin cells (turned into stem cells in a lab) from people with various heart and blood vessel conditions. It aims to find new ways to understand and treat these diseases.
London, OntarioAges 18–80 - NCT06431711Recruiting
Eye scan study for brain small vessel disease
This study uses a special eye scan (OCTA) to check the health of tiny blood vessels in the back of the eye. It may help doctors understand small vessel disease in the brain and find easier ways to monitor it.
Hangzhou, ZhejiangAges 35 years+ - NCT05779215Recruiting
Registry for acute stroke with blocked brain arteries
This study records information about people who have a new acute ischemic stroke caused by a blockage in a larger or medium-sized brain artery. It may help doctors better understand outcomes and care for this stroke type, using data from many patients.
Beijing, Beijing MunicipalityAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.