Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11 - NCT07299487Recruiting
Helping diagnose vertigo patients faster
This trial looks at how well a decision tree helps diagnose vertigo in the emergency room. It compares the diagnoses made by medical students to those made by an ear, nose, and throat (ENT) doctor to see if the tool speeds up and improves accuracy.
StrasbourgAges 18 years+ - NCT07303023RecruitingPhase 3
Personalized neck radiation to prevent cancer spread
This trial tests whether a personalized radiation plan for the neck can prevent cancer from spreading in people with nasopharyngeal carcinoma. It's for those whose cancer hasn't spread beyond the head and neck area.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07299513Recruiting
Study of airway and digestive fistulas in adults
This study looks at adults who had an abnormal connection between their airway and digestive tract, called an aerodigestive fistula, diagnosed between 2014 and 2023. It aims to understand these conditions better by reviewing patient data from the University Hospital of Strasbourg.
StrasbourgAges 18 years+ - NCT07299474Recruiting
Lavender scent for anxiety and pain during awake ENT procedures
This study tests whether smelling lavender essential oil during an awake ear, nose, or throat procedure can help reduce anxiety and pain. If you qualify, you may receive the lavender scent during your procedure and report how you feel.
Los Angeles, CaliforniaAges 18 years+ - NCT07299448Recruiting
Parkinson's and swallowing: what drives difficulty?
This study looks at why some people with Parkinson's have trouble swallowing (dysphagia) and how the brain adapts. It aims to understand the condition better, which could lead to better treatments.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07300800Recruiting
PRP injection for voice after vocal cord surgery
This trial tests if injecting platelet-rich plasma (PRP) during vocal cord surgery helps your voice heal faster and better. It is for adults with benign growths like polyps or nodules that haven't improved with voice therapy.
Banī Suwayf, EgyptAges 18–50 - NCT07304024RecruitingPhase 1/Phase 2
Testing a drug and sound therapy for age-related hearing difficulty
This trial tests whether a combination of an antihistamine (clemastine fumarate) and specially designed sounds can improve how the brain processes hearing in middle-aged adults with mild hearing loss. It might help if you have trouble understanding speech in noisy settings.
Aurora, ColoradoAges 45–65 - NCT07288827Recruiting
Study of airway sensitivity in primary ciliary dyskinesia
This study looks at how the airways in people with primary ciliary dyskinesia (PCD) react to certain triggers. It aims to understand if these airways are more sensitive, which could help improve treatment for breathing problems.
Indianapolis, IndianaAges 6 years+ - NCT07290621RecruitingPhase 2
Toripalimab with standard treatment for HPV-positive throat cancer
This study tests adding a new immunotherapy drug (toripalimab) to standard chemo for HPV-positive throat cancer. It aims to see if this combination works better than chemo alone for patients whose cancer has spread to nodes but not to other parts of the body.
Chicago, IllinoisAges 18 years+ - NCT07295548Recruiting
Can head and neck flap patients skip the ICU?
This trial compares whether patients recovering from head and neck cancer flap surgery need to stay in the intensive care unit (ICU) or can be safely cared for on a regular surgical ward. The goal is to see if a less intensive recovery is safe and equally effective.
Pavia, LombardyAges Any age - NCT07295990Recruiting
Tongue exercises for people with ALS
This trial tests whether simple tongue-strengthening exercises can help people with ALS who have mild swallowing trouble. If you have ALS and notice your tongue getting weaker, this study may help you keep your swallowing strength.
Davie, FloridaAges 18–99 - NCT07287891Recruiting
Predicting brain causes of dizziness in the ER
This study is observing patients who come to the emergency department with vertigo, dizziness, or unsteadiness. Researchers want to predict which of these symptoms are caused by a brain problem (central nervous system), helping doctors make fast and accurate decisions.
Pavia, PaviaAges 18 years+ - NCT07288580RecruitingPhase 1/Phase 2
Gene therapy for children with inherited deafness
This trial tests an injection called EHT102 for children who have severe or profound hearing loss due to mutations in the Otoferlin gene. The goal is to see if the treatment can restore or improve hearing.
Shanghai, Shanghai MunicipalityAges 1–17 - NCT07290140Recruiting
Balloon treatment for chronic sinusitis
This trial tests a balloon coated with a medicine (paclitaxel) to treat chronic sinusitis. It may help reduce inflammation and improve sinus drainage in adults with long-lasting sinus problems.
Birmingham, AlabamaAges 18 years+ - NCT07294976Recruiting
Testing maximum gain in bone-anchored hearing devices
This trial tests the maximum sound gain you can get from your bone-anchored hearing device. If you already use an Oticon Medical compatible system and have mixed hearing loss, this study will check how well your device performs.
GothenburgAges 18 years+ - NCT07281417RecruitingPhase 2
Testing adding cemiplimab to chemo before surgery for sinus cancer
This trial tests whether adding the immunotherapy drug cemiplimab to standard chemotherapy before surgery helps treat sinonasal squamous cell carcinoma. The goal is to see if this combination reduces tumors more effectively than chemotherapy alone.
Irvine, CaliforniaAges 18 years+ - NCT07286201Enrolling by invitation
Nasal packing with steroid to improve sinus surgery results
This study tests a special nose dressing that slowly releases a steroid to reduce inflammation and improve healing after sinus surgery for chronic sinusitis with or without nasal polyps.
Colorado Springs, ColoradoAges 18 years+ - NCT07282028RecruitingPhase 2/Phase 3
Spectacle hearing aid study for adults with mild to moderate hearing loss
This study tests a new hearing aid built into glasses for people who have mild to moderate hearing trouble, especially in noisy places. It aims to see if the glasses help you hear better without needing a traditional hearing aid.
Tel AvivAges 18 years+ - NCT07279441Recruiting
Cochlear Implants and Listening Effort Study
This study looks at how much mental effort it takes for people with normal hearing or a cochlear implant to listen in different situations. Researchers want to learn how hearing and thinking work together, which could help improve cochlear implant technology.
Waltham, MassachusettsAges 18–80 - NCT07287774Recruiting
Testing a new noise-reduction feature for hearing aids
This trial is testing a new computer program that helps hearing aids reduce background noise. It might make it easier for people with mild to moderate hearing loss to hear in noisy places.
West Lafayette, IndianaAges 18 years+ - NCT07283653Recruiting
Using DIGEST™ to measure swallowing problems in cancer patients
This trial is testing how well a tool called DIGEST™ works to measure swallowing difficulties (dysphagia) in cancer patients who have a special x-ray called a Modified Barium Swallow. The goal is to help doctors better understand and treat swallowing problems.
Houston, TexasAges 18 years+ - NCT07282483RecruitingPhase 2
Chinese medicine mouthwash for radiation mouth sores
This trial tests whether a traditional Chinese medicine mouthwash and oral liquid can help prevent or reduce mouth sores caused by radiation therapy for head and neck cancer. If you are getting radiation and are at risk for these painful sores, this study might offer you extra relief.
Chengdu, SichuanAges 18–65 - NCT07281508RecruitingPhase 3
Preventing hearing loss from cisplatin in head and neck cancer
This trial tests whether a gel placed in the ear can protect against hearing loss caused by high-dose cisplatin chemotherapy. It is for people with head and neck cancer who are scheduled to receive a certain amount of cisplatin.
Amsterdam, North HollandAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.