Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06861751Recruiting
Smartphone overuse and jaw proprioception in teens
This trial looks at how heavy smartphone use affects neck posture, neck muscle endurance, and jaw awareness in teenagers aged 17-19. It aims to understand if long-term phone use is linked to these physical changes.
Al MansurahAges 17–19 - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT05938166Recruiting
Training foreign caregivers with an augmented reality system
This study tests whether an augmented reality (AR) training system can help foreign care workers learn how to provide care. It involves Indonesian caregivers training for caring for older adults in Kaohsiung, with tests based on the older adult’s ability to follow instructions.
Kaohsiung City, Sanmin DistAges 21–65 - NCT07325539RecruitingPhase 2
Radiation and immunotherapy with chemo for nose and throat cancer
This trial tests combining low-dose radiation with an immunotherapy drug (toripalimab) and chemotherapy for people whose nose and throat cancer has come back or spread. The goal is to see if this combination works better than standard treatments.
Guangzhou, GuangdongAges 18–65 - NCT07327710Enrolling by invitation
Brain-Computer Interface and Electrical Stimulation for Facial Paralysis
This trial tests a non-invasive treatment that combines a brain-computer interface with mild electrical stimulation to help people with one-sided facial paralysis regain movement. It aims to improve facial muscle function by retraining the brain and muscles together.
Changzhou, JiangsuAges 18–75 - NCT07328854RecruitingPhase 3
Lower versus standard radiation in stage II nasopharyngeal cancer
This trial compares a lower dose of radiation (40.2 Gy) to the standard dose (49.2 Gy) for patients with stage II nasopharyngeal carcinoma that has shrunk after initial chemoimmunotherapy. The goal is to see if the lower dose works just as well while potentially causing fewer side effects.
Hefei, AnhuiAges 18–75 - NCT07328841RecruitingPhase 3
Lower radiation dose study for advanced nasopharyngeal cancer
This trial compares a lower dose of radiation to the standard dose for people with advanced nasopharyngeal cancer that shrank after chemotherapy and immunotherapy. The goal is to see if a lower dose works just as well with fewer side effects.
Guangzhou, GuangdongAges 18–70 - NCT07327216RecruitingPhase 3
Comparing two inhalations for mouth sores from cancer treatment
This trial tests if an inhaled medication called Sapylin can prevent or reduce severe mouth sores caused by chemoradiation, compared to a standard steroid inhalation. It is for people with advanced nasopharyngeal cancer who have not yet started treatment.
Zhanjiang, GuangdongAges 18–75 - NCT07326358Recruiting
AI help for doctors finding problems in nose and throat exams
This study uses artificial intelligence to help doctors better see and find issues during nose and throat camera exams. If you are getting this exam and agree to participate, your images may be checked by the AI system to see if it can improve detection.
ShanghaiAges 18 years+ - NCT07332247RecruitingPhase 2
Immunotherapy plus chemo then immediate vs selective re-radiation for advanced recurrent NPC
This trial is for people with nasopharyngeal cancer that has come back in the same area. It tests whether giving additional radiation right after chemo plus immunotherapy works better than waiting to see if more radiation is needed later.
Guangzhou, GuangdongAges 18–70 - NCT07326345Recruiting
Study comparing ways to widen the upper jaw
This trial tests different methods to widen a narrow upper jaw and see how they affect the nose and face bones. It is for people 15 and older who have a crossbite (when upper teeth sit inside lower teeth).
Istanbul, FatihAges 15 years+ - NCT05922176Recruiting
Microneedle patch testing to predict allergy treatment response
This study uses a small microneedle patch to collect skin-related samples to help predict how well allergy immunotherapy may work. It includes people with house dust mite allergy and also a healthy control group, so researchers can compare biomarker results.
SeoulAges 19–60 - NCT06870435Recruiting
Screening for nasopharyngeal cancer with blood tests
This study compares three different blood tests to see which works best for spotting nasopharyngeal cancer early in people at higher risk. If you live in certain areas of China, you may be able to join.
Zhuhai, GuangdongAges 30–69 - NCT07323862Recruiting
Improving hearing in noise for people with two cochlear implants
This study tests a new way to help people with cochlear implants hear speech better in noisy places, while still being able to tell where sounds come from. It compares different sound processing strategies to find the best one for daily life.
Champaign, IllinoisAges 18 years+ - NCT07317947Recruiting
Nasal tip shaping with a cartilage graft in first-time rhinoplasty
This trial tests a surgical technique that uses your own nasal cartilage to improve the shape and position of your nasal tip. It's for people having their first rhinoplasty (nose job) for cosmetic or breathing reasons.
Kafr ash ShaykhAges 18–60 - NCT07317154RecruitingPhase 1
Dendritic cell vaccine for HPV type 6 recurrent respiratory papillomatosis
This Phase 1 trial is testing a vaccine made from your own immune cells (dendritic cells) that may help your body fight the virus causing recurrent papillomas in your voice box. It is for people whose papillomas are caused by HPV type 6, who have had at least one recurrence in the past year.
Scottsdale, ArizonaAges 18 years+ - NCT07315945Recruiting
Allergic rhinitis severity survey in ENT visits
This study is testing a questionnaire to measure how severe your allergic rhinitis (hay fever) symptoms are during your ear, nose, and throat (ENT) checkups. If you are an adult with allergic rhinitis being seen at the ENT department, you may be asked to fill out the survey to help improve care.
StrasbourgAges 18 years+ - NCT04365036RecruitingPhase 3
Check if PD-1 plus chemo-radiation helps early nasal lymphoma
This trial studies whether adding toripalimab (an immune therapy that targets PD-1) to standard chemo-radiation works better for newly diagnosed early-stage nasal natural killer/T-cell lymphoma. It’s designed to see if the combined treatment can improve outcomes while staying safe.
Guangzhou, GuangdongAges 18–75 - NCT07308015RecruitingPhase 4
Hyaluronic acid nasal rinse for dry nose
This trial tests if a sodium hyaluronate nasal spray helps people with dry nose symptoms like crusting, bleeding, and stuffiness. It may be an option if your nose feels dry and has thick mucus or scabs.
Changchun, JilinAges 18–75 - NCT07307833Enrolling by invitation
Immune therapy and its effect on balance
This study checks if certain immune therapy drugs affect your balance or inner ear function. It involves people starting treatment with one or two of these drugs for cancer.
Scottsdale, ArizonaAges 18 years+ - NCT07309978Recruiting
Comparing ultrasound and physical measurements for predicting difficult airways
This study compares two methods—ultrasound of the upper airway and standard physical measurements—to predict which patients may have a difficult airway during surgery. The goal is to find a more reliable way to prepare for safe anesthesia.
AnkaraAges 18–99 - NCT05935618Recruiting
Occupational therapy rehab for frail older adults with swallowing trouble
This trial tests an occupational therapy–based rehabilitation program to help frail older adults with swallowing problems work more safely and comfortably. You may be considered if your swallowing screen results fall in a specific range and you can participate in the therapy and consent process.
HvidovreAges 65 years+ - NCT07298499Enrolling by invitation
Hearing aids and sound therapy for tinnitus
This trial tests using hearing aids with built-in tinnitus maskers to see if they help adults who have both hearing loss and ringing in the ears. It aims to find out if these devices improve hearing and reduce tinnitus symptoms.
Broomfield, ColoradoAges 18 years+ - NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.