Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT07326345Recruiting
Study comparing ways to widen the upper jaw
This trial tests different methods to widen a narrow upper jaw and see how they affect the nose and face bones. It is for people 15 and older who have a crossbite (when upper teeth sit inside lower teeth).
Istanbul, FatihAges 15 years+ - NCT07299513Recruiting
Study of airway and digestive fistulas in adults
This study looks at adults who had an abnormal connection between their airway and digestive tract, called an aerodigestive fistula, diagnosed between 2014 and 2023. It aims to understand these conditions better by reviewing patient data from the University Hospital of Strasbourg.
StrasbourgAges 18 years+ - NCT07350681Recruiting
Jaw surgery's effect on foot pressure and posture
This study looks at how jaw surgery (orthognathic surgery) affects your foot pressure and body posture. You might join if you are already planning this surgery as part of your orthodontic treatment.
Istanbul, FatihAges 18 years+ - NCT07287891Recruiting
Predicting brain causes of dizziness in the ER
This study is observing patients who come to the emergency department with vertigo, dizziness, or unsteadiness. Researchers want to predict which of these symptoms are caused by a brain problem (central nervous system), helping doctors make fast and accurate decisions.
Pavia, PaviaAges 18 years+ - NCT07340411RecruitingPhase 2
Herbal nose rinse after sinus surgery
This trial is testing whether rinsing the nose with a Chinese herbal medicine after surgery helps people with chronic sinusitis recover better. It compares the herbal rinse to usual care, with the goal of reducing symptoms and the need for more treatments.
TaichungAges 18–90 - NCT07264322Recruiting
Real-time imaging of healthy swallowing during a barium swallow test
This study uses a special X-ray test (called a barium swallow) to take real-time images of how your throat and voice box work normally while swallowing. Researchers want to learn more about healthy swallowing to help future patients.
Hangzhou, ZhejiangAges 18–75 - NCT07236580Recruiting
Breathing exercises for teens with ear problems and smoke exposure
This study tests whether special breathing exercises can help teenagers with a blocked eustachian tube (the tube that connects the ear to the throat) whose parents smoke. It aims to improve ear and lung function.
Giza, DokkiAges 13–17 - NCT07267455Recruiting
Personalized brain stimulation for chronic tinnitus
This study tests a noninvasive brain stimulation technique called personalized transcranial magnetic stimulation (TMS) to see if it can reduce the loudness or annoyance of chronic tinnitus. Participation involves daily sessions for 5 days at the hospital.
Guangzhou, GuangdongAges 18–80 - NCT07177495Recruiting
Bone graft mix for sinus lift in upper jaw
This trial tests a bone graft made of your own bone mixed with cow bone (Deproteinized Bovine Bone) to rebuild the upper jaw in the sinus area. It compares this mixed bone graft to using only cow bone for a sinus lift, helping you get implants when there is not enough bone height.
Cairo, Giza GovernorateAges 30 years+ - NCT07035873Recruiting
Remote check-ups for teens with cochlear implants
This trial tests if teens with Advanced Bionics cochlear implants can do programming and hearing tests from home instead of going to the clinic. It could make follow-up care easier and more convenient.
Columbus, OhioAges 13–20 - NCT07064096Recruiting
Mental imagery plus balance rehab for dizziness in young adults
This study tests whether adding mental imagery (picturing movements in your mind) to standard balance exercises can help young adults with a one-sided inner ear balance problem feel less dizzy and improve their balance.
Gujar Khān, Punjab ProvinceAges 20–40 - NCT06254911RecruitingPhase 2
Immunotherapy before surgery for HPV-related throat cancer
This trial tests whether giving the drug atezolizumab before surgery can help shrink HPV-related throat cancer and improve outcomes. Atezolizumab helps your immune system fight cancer cells.
Atlanta, GeorgiaAges 18 years+ - NCT07156227RecruitingPhase 1
Testing camonsertib with radiation for returning head and neck cancer
This study tests whether adding the drug camonsertib to radiation therapy can help people whose head and neck cancer has come back in a spot that was already treated with radiation. Camonsertib is an experimental drug that may help radiation work better.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05788536RecruitingPhase 1/Phase 2
Gene therapy study for OTOF-related hearing loss
This trial tests a one-time gene therapy delivered into the ear to improve hearing in people with certain OTOF gene changes. It studies safety and how well the treatment can work, especially in children and infants, as doctors monitor hearing tests for up to 48 weeks.
Los Angeles, CaliforniaAges Any age - NCT07245030Recruiting
Virtual reality vs show-do for dental anxiety in kids with hearing loss
This trial tests whether virtual reality or a show-do method works better to reduce dental anxiety in children who have moderate to severe hearing loss. If your child needs a dental cleaning, this could help make the visit less stressful.
Giza, Giza GovernorateAges 6–12 - NCT06982105RecruitingPhase 4
Comparing two antibiotics for children with MRSA bone or head infections
This study compares two oral antibiotics, TMP-SMX and clindamycin, to see which works better for children with MRSA infections in bones, joints, or head/neck areas. It aims to find the best treatment after initial IV therapy.
Indianapolis, IndianaAges 2 months–18 years - NCT04743141RecruitingPhase 3
Long-term migraine medicine study for kids with migraine attacks
This Phase 3 study checks the long-term safety of rimegepant, a migraine treatment, in children and teens. You might join if your child has had migraine for at least 6 months and still gets a certain number of moderate-to-severe migraine attacks.
Scottsdale, ArizonaAges 6–17 - NCT04198766RecruitingPhase 1/Phase 2
New OX40 immunotherapy for advanced solid tumors
This trial tests a new immunotherapy drug (INBRX-106) alone or with Keytruda (pembrolizumab) for adults with advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug can help the immune system fight cancer.
Duarte, CaliforniaAges 18 years+ - NCT07734298Recruiting
Ultrasound vs. scope for swallowing problems after ICU breathing tube
This study compares two ways to check swallowing after a breathing tube is removed in the ICU: one uses an ultrasound machine, the other uses a small camera through the nose. If you qualify, you may help doctors find the best method to spot swallowing issues early.
Querétaro City, QuerétaroAges 18 years+ - NCT06638944RecruitingPhase 2
Wearable device training for swallowing after stroke or Parkinson's
This study tests a wearable device that gives feedback on swallowing exercises. It may improve swallowing safety after a stroke or for people with Parkinson's disease.
Champaign, IllinoisAges 50–90 - NCT07731321Enrolling by invitation
Are Earplug Instructions Better One Way Or Another?
This study compares different ways of teaching people how to use earplugs. It will look at which method works best to protect hearing in a noisy workplace.
Chiang MaiAges 20–60 - NCT06543823Recruiting
New bandage for throat surgery pain relief
This trial tests a special wound dressing (SUPRATHEL 250) placed inside the throat after tonsil removal. It aims to see if it helps throat wounds heal faster with less pain.
Stuttgart, Baden-WurttembergAges 18 years+ - NCT06608017RecruitingPhase 2/Phase 3
Yupingfeng powder for allergic rhinitis
This trial tests whether Yupingfeng powder, a traditional Chinese herbal remedy, can help relieve allergic rhinitis symptoms like sneezing and a runny nose. It may be an option if your allergic rhinitis is linked to a deficiency in lung and spleen energy (a concept in Chinese medicine).
ShatinAges 18 years+ - NCT07726147RecruitingPhase 1
Testing a new allergy shot for Japanese cedar pollen
This trial tests a new allergy shot (ITI-9001) for people with Japanese cedar pollen allergy. It aims to see if the shot is safe and can reduce allergy symptoms. The study is for people who have not tried immunotherapy before.
Tokyo, Shinjuku-kuAges 1.5 years–65 years
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.