Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06910865Recruiting
Study of inner ear fluid swelling on MRI
This trial studies how inner ear fluid swelling seen on MRI relates to symptoms like dizziness or hearing loss. It may help doctors better diagnose and treat balance disorders.
StrasbourgAges 18 years+ - NCT05710809Recruiting
Exercise and health check study for older colorectal cancer patients
This trial looks at sarcopenia (loss of muscle strength/size) and vertigo (feeling dizzy or off-balance) in older adults with colorectal cancer. It tests whether a structured, exercise-based approach can help these issues alongside cancer care.
CopenhagenAges 65 years+ - NCT04997577Recruiting
Study of speech listening with high mental effort
This study tests how well you can understand speech when the task is mentally demanding. It may help researchers understand hearing and brain processing in older adults.
College Park, MarylandAges 65–85 - NCT07219849RecruitingPhase 2
Testing a new nasal spray for seasonal allergies
This study tests a new nasal spray (ALDP001) in adults with seasonal allergies to ragweed. It aims to find the best dose and how often to use it.
Mississauga, OntarioAges 18–65 - NCT07216430RecruitingPhase 2
Safety and efficacy of a pneumococcal vaccine in young kids
This study tests a new pneumococcal vaccine (wSp) in young children who have already had 3 doses of a standard pneumococcal shot. It aims to see if the new vaccine is safe and works well to protect against serious infections.
Pittsford, New YorkAges 5 months–7 months - NCT07216937Recruiting
Comparing 3D-printed vs. regular ear tip comfort
This study compares how comfortable 3D-printed ear tips are versus regular ear tips for people with normal hearing.
Tucson, ArizonaAges 18–89 - NCT07218913RecruitingPhase 1
Testing a drug to reduce ear damage from chemo in testicular cancer
This trial tests whether adding Pedmark (sodium thiosulfate) to cisplatin chemotherapy can protect hearing in men with stage II or III testicular germ cell tumors. It aims to reduce the risk of drug-related ear damage while still treating the cancer.
Duarte, CaliforniaAges 18 years+ - NCT07212530Recruiting
EmoTIChealth: A game to boost teen health
This trial tests a serious video game designed to help teenagers learn skills for better health. It's for 12- to 16-year-olds who speak Spanish and have internet access.
Valencia, ValenciaAges 12–16 - NCT07217938RecruitingPhase 2
Testing statins for swallowing problems after radiation
This study tests whether a common cholesterol-lowering drug (pravastatin, a type of statin) can reduce swallowing problems caused by past radiation for head and neck cancer. If you have had radiation at least 2 years ago and still have trouble swallowing, this trial may help find a new way to ease those symptoms.
Melbourne, VictoriaAges 18 years+ - NCT06912243Recruiting
Animation to calm kids before ear tube surgery
This study tests if showing children an educational animation before ear tube surgery can lower their fear and anxiety. It’s a simple, short video that explains what will happen, and the goal is to help your child feel calmer.
Merkez, BartınAges 6–10 - NCT04706234Recruiting
Check swallowing and voice function in neurodegenerative diseases
This study looks at how well the throat and voice-related functions work in people with certain long-term brain or nerve conditions. It uses a specific throat exam during FEES to better understand swallowing and laryngopharyngeal (throat-area) function.
Innsbruck, TyrolAges 18 years+ - NCT05508347RecruitingPhase 2
Testing a new antibody with chemo for locally advanced throat cancer
This study tests nituzumab (a targeted antibody) added to standard induction chemotherapy versus placebo plus chemotherapy. It aims to improve tumor control and safety for people with locally advanced nasopharyngeal (throat) cancer.
Chengdu, SichuanAges 18–70 - NCT06752239RecruitingPhase 3
Optimizing radiation to protect thyroid in nasopharyngeal cancer
This trial tests a way to adjust radiation therapy to better protect the thyroid gland during treatment for nasopharyngeal carcinoma. It aims to reduce thyroid damage while still effectively treating the cancer.
Nanchang, JiangxiAges 18–70 - NCT06921161Recruiting
TongueFit therapy for swallowing problems in children
This study tests a new device called TongueFit that helps children strengthen their tongue muscles to improve swallowing. If your child has trouble swallowing due to weak tongue muscles, this therapy may help.
Jakarta, Jakarta Special Capital RegionAges 3–16 - NCT06928714Recruiting
Feeding problems in children at Amiens Hospital
This study is for children with long-term feeding difficulties that involve medical, nutritional, emotional, or skill-related problems. It aims to understand these challenges better and improve care.
AmiensAges Up to 18 years - NCT07209189RecruitingPhase 2
Chemo and immunotherapy before surgery for head and neck cancer
This trial tests a combination of chemotherapy and an immunotherapy drug called Toripalimab before surgery for certain head and neck cancers. The goal is to see if this approach can reduce the extent of treatment needed while still being effective.
Baltimore, MarylandAges 18 years+ - NCT07211711Recruiting
Splint therapy for tinnitus linked to jaw joint issues
This trial tests if a custom mouthpiece (occlusal splint) can relieve ringing in the ears (tinnitus) that started along with jaw or face pain (TMD). It aims to see if stabilizing the jaw helps reduce both the noise in your ears and the discomfort.
São Paulo, São PauloAges 18 years+ - NCT07205354Recruiting
Food preference tool for older hospital patients
This study is creating a tool to better understand what foods older patients prefer, especially those with swallowing difficulties. It could help hospitals make meals more enjoyable and safer for you.
LyonAges 70 years+ - NCT07205484Enrolling by invitationPhase 2
Early communication help for deaf or hard of hearing toddlers
This study looks at the long-term effects of early communication support for toddlers who are deaf or hard of hearing. It may help show how early intervention can improve language and social skills.
Evanston, IllinoisAges 5–8 - NCT06551857Recruiting
How cancer treatments affect hearing and thinking
This study looks at how common cancer treatments (certain chemotherapies and radiation to the head and neck) affect hearing in noisy places, thinking skills, and quality of life related to hearing. It aims to understand and possibly reduce these side effects.
Turku, Southwest FinlandAges 18–75 - NCT06493825Recruiting
Mindfulness app for kids with severe tinnitus or misophonia
This trial tests whether a virtual reality mindfulness app can help children aged 10–18 with severe tinnitus or misophonia feel better mentally. It compares the mindfulness app to a placebo (sham) version.
Aurora, ColoradoAges 10–18 - NCT06920368Recruiting
Preventing complications after nose surgery
This trial tests different methods to reduce complications after septoplasty, a surgery to fix a crooked nasal septum. It may help if you have a deviated septum that causes symptoms like trouble breathing.
TantaAges 16–60 - NCT06932328RecruitingPhase 2
Granules for acute sore throat with wind-heat pattern
This trial tests whether Qinqiao Yan Shu Granules can help adults with acute pharyngitis (sore throat) that started within 48 hours. You must have a specific pattern called wind-heat invading the exterior, and at least moderate throat pain.
Harbin, HeilongjiangAges 18–65 - NCT06846385RecruitingPhase 2/Phase 3
Testing a new shot for severe seasonal hay fever
This study tests a new injection called MG-K10 for people with moderate-to-severe seasonal hay fever that isn't well controlled by standard treatments like nasal sprays or antihistamines. The goal is to see if it can reduce your allergy symptoms over the pollen season.
Beijing, Beijing MunicipalityAges 18–75
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.