Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT03925389Recruiting
Analyzing results after external septorhinoplasty for breathing issues
This trial looks at how well an external septorhinoplasty (surgery to improve the nasal passage) works for people with long-term nasal blockage. It mainly involves filling out questionnaires so the researchers can analyze outcomes over time.
AntwerpAges 18 years+ - NCT03979235Recruiting
Rehab effectiveness programs for people after stroke
This trial is testing rehabilitation programs by studying how well they work for people with movement problems after a stroke. You may be able to join if you can complete the rehab assessment and follow testing instructions.
BeijingAges 18–80 - NCT03988764Recruiting
Checking monogenic diabetes wrongly labeled as type 1
This trial looks at people who were diagnosed with diabetes before age 25 as either type 1 or “not sure which type.” It may help confirm whether the cause is genetic (monogenic) rather than type 1, which can change treatment choices.
Montreal, QuebecAges 1 day–25 years - NCT03996824Recruiting
Gene therapy study for certain vestibular schwannoma surgeries
This trial tests delivering gene therapy into the inner-ear hearing balance nerve cells during surgery for vestibular schwannoma. It may help by improving how the inner ear functions after tumor removal, but you must meet several specific surgery and safety requirements.
Le Kremlin-Bicêtre, Île-de-France RegionAges 18 years+ - NCT04340024Recruiting
Testing blood markers linked to how well radiation works
This study looks for “biomarkers,” or measurable signs (often from blood or samples), that may show which cancers respond better to radiation therapy. It may help doctors choose radiation treatment more precisely, especially for people who had significant side effects before.
SingaporeAges 21–99 - NCT07702149Recruiting
Diet for Behcet's disease patients with ringing in the ears
This trial tests whether a special diet can help ringing in the ears (tinnitus) in people with Behcet's disease who also have obesity. The goal is to see if dietary changes reduce tinnitus symptoms.
Giza, DokkiAges 40–55 - NCT07178301RecruitingPhase 2
Lower radiation dose for HPV-related throat cancer
This trial tests whether a lower dose of radiation to the neck is safe and effective for people with HPV-related oropharyngeal cancer. It may reduce side effects while still treating the cancer.
Chicago, IllinoisAges 18 years+ - NCT07703800Recruiting
Testing a better sound fitting for single-sided deaf cochlear implant users
This study tests if a cochlear implant fitting based on your ear's anatomy helps you hear speech in noisy places and enjoy music more. It is for people who are deaf in one ear and use a MED-EL cochlear implant.
AntwerpAges 18 years+ - NCT07401732Recruiting
Dysphagia in rheumatoid arthritis study
This study looks at swallowing problems (dysphagia) in people with rheumatoid arthritis to understand how common they are and what might cause them. It uses a flexible scope through the nose to examine swallowing function.
Tanta, ElgharbiaAges 18 years+ - NCT05215197Recruiting
Platelet-rich fibrin placed during cochlear implant surgery
This trial studies whether applying a special healing material during cochlear implant surgery improves outcomes for people with nerve-based hearing loss. You might be eligible if you need a cochlear implant using a specific electrode and do not have certain inner-ear conditions.
DenizliAges Any age - NCT05451004RecruitingPhase 3
SPECT-CT test to target neck radiation on one side
This study tests whether using a special scan (SPECT-CT) can guide radiation treatment to only the safer/needed side of the neck in people with a one-sided oropharyngeal cancer. It aims to keep cancer control while potentially reducing side effects from unnecessary radiation.
Corona, CaliforniaAges 18 years+ - NCT04019548RecruitingPhase 3
Test swallowing and quality of life during chemo-radiation for throat cancer
This study looks at how well people swallow and how their quality of life changes during standard chemo-radiation for newly diagnosed throat (oropharyngeal) cancer. The goal is to better understand swallowing side effects so care can improve.
BrusselsAges 18 years+ - NCT04057209Recruiting
Voice outcomes after laser surgery vs radiation for early vocal cord cancer
This trial compares two treatments—CO2 laser surgery through the mouth versus one-vocal-cord irradiation—for early-stage larynx (voice box) cancer. It aims to see which option better preserves voice quality after treatment.
ParisAges 18 years+ - NCT04066348RecruitingPhase 2
TNF medication trial for blast-related tinnitus
This Phase 2 study tests whether a TNF-α medicine can reduce tinnitus symptoms after blast or loud noise exposure, sometimes with traumatic brain injury. You may be a candidate if your tinnitus is at least moderately severe and stable over time, and if you meet other health and medication rules.
Celebration, FloridaAges 18 years+ - NCT04070937Recruiting
Imaging findings and balance function in bilateral vestibulopathy
This study compares CT/MRI imaging results (radiological lesions) with balance system function tests in people with bilateral vestibulopathy. The goal is to see whether changes seen on scans match how well your inner-ear/balance nerves are working, which could improve understanding and future treatment decisions.
Hasselt, LimburgAges 18–90 - NCT04083417RecruitingPhase 4
Sore throat study comparing antibiotics versus no antibiotics
This trial looks at whether phenoxymethylpenicillin (an antibiotic) helps people with a certain type of sore throat more than not using antibiotics. You may qualify if your symptoms match a likely bacterial cause and a rapid test for strep is negative.
JönköpingAges 15 years+ - NCT04085900Recruiting
Screening test for nasopharyngeal cancer blood markers
This study screens people in certain cities to see whether signs in the blood related to a virus (EBV) can help find nasopharyngeal cancer earlier. It may help identify higher-risk people so they can be checked sooner.
Zhongshan, GuangdongAges 30–69 - NCT04136886RecruitingPhase 3
Chemo trial for return of advanced nasopharyngeal cancer
This Phase 3 study tests a chemotherapy plan for people whose nasopharyngeal cancer has come back locally (T3/T4). It aims to see if treatment given after return of cancer can help control the disease without spreading to distant organs.
Guangzhou, GuangdongAges 18–70 - NCT04142697Recruiting
Study of how you feel motion with sight and balance
This study looks at how people with normal health—and people with balance (vestibular) loss—perceive motion using their eyes and inner ear. You may help researchers understand how vision and balance systems work together.
Rochester, New YorkAges 18–80 - NCT04151082RecruitingPhase 1/Phase 2
Steroid therapy for late nerve damage after throat cancer radiation
This trial tests whether high-dose steroids (prednisone or methylprednisolone) can improve symptoms of nerve damage that may occur years after radiation treatment for oropharyngeal cancer. It includes a registry for tracking similar nerve issues in head and neck cancer survivors.
Houston, TexasAges 18 years+ - NCT04152551RecruitingPhase 4
Bisphosphonate use and hearing loss in type 1 osteogenesis imperfecta
This study looks at whether bisphosphonate treatment affects hearing loss in people with type 1 osteogenesis imperfecta. If you qualify, it may help researchers understand if treatment can protect hearing over time.
New York, New YorkAges 6–100 - NCT04190953Recruiting
Braces and expanders in kids to improve airflow space
This study looks at how jaw and palate treatments affect airflow through the upper airway in children with a specific bite and jaw shape. It may help researchers understand which treatments improve space for breathing and related pressure changes.
Edmonton, AlbertaAges 8–14 - NCT04192656RecruitingPhase 4
PAP treatment for sudden hearing loss with sleep apnea
This trial tests whether using PAP (a breathing device for sleep apnea) can improve sudden hearing loss that happens alongside obstructive sleep apnea. It may help by reducing stress on the body during sleep and supporting hearing recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT04192773RecruitingEarly Phase 1
Brain-scan study of IV lidocaine for tinnitus
This early study uses an MRI/brain scan to see how IV lidocaine affects brain activity in people with tinnitus, and also compares it with people without tinnitus or with different hearing patterns. It may help researchers understand whether lidocaine could change tinnitus signals in the brain.
Boston, MassachusettsAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.