Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07264322Recruiting
Real-time imaging of healthy swallowing during a barium swallow test
This study uses a special X-ray test (called a barium swallow) to take real-time images of how your throat and voice box work normally while swallowing. Researchers want to learn more about healthy swallowing to help future patients.
Hangzhou, ZhejiangAges 18–75 - NCT07258979RecruitingPhase 1/Phase 2
YL201 and Toripalimab with or without Cisplatin for Nasopharyngeal Cancer
This trial tests a new drug combination for people with advanced or recurrent nasopharyngeal cancer. It aims to see if YL201 plus Toripalimab (and sometimes cisplatin) can help when standard treatments are not an option.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07252492Recruiting
Testing a new hearing device for people with hearing loss
This study tests a new hearing device called 'Audiocap' to see if it helps people with mild to moderate hearing loss hear better. It may be an option if you are getting your first hearing aid.
Lyon, FranceAges 18 years+ - NCT06890260Recruiting
Electroacupuncture plus microneedle for allergic rhinitis
This trial tests a 4-week treatment of electroacupuncture combined with microneedle knife for people with moderate to severe allergic rhinitis. It may help reduce symptoms without relying on standard allergy medications.
Hangzhou, ZhejiangAges 18–75 - NCT07250113Enrolling by invitation
WeCareToFeedDysphagia study for care partners of older adults
This trial tests a program to help care partners of older adults with Alzheimer's disease and swallowing problems. It aims to reduce stress and improve care at home.
Manhasset, New YorkAges 18 years+ - NCT07251140Recruiting
Swallowing study with a new microphone device
This study tests a new microphone device to see if it can help find swallowing problems in people who have had a stroke. If you are already scheduled for a swallowing test, you may be able to take part.
Atlanta, GeorgiaAges 40–85 - NCT05094570RecruitingPhase 4
Dupilumab for nasal polyps with staph bacteria
This trial studies whether dupilumab (an injection) can reduce staph bacteria in the nose and make the nose’s microbes more diverse in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). If you already have a plan to start dupilumab as standard care, the study may help doctors better understand why it works.
Charlottesville, VirginiaAges 18–65 - NCT07245329Recruiting
Expanded sinus surgery with throat tissue ablation for nasal polyps
This trial tests a more thorough sinus surgery combined with removing lymphoid tissue in the throat to see if it helps people with nasal polyps. Researchers want to know if this approach reduces inflammation and improves symptoms.
Wuhan, HubeiAges 18–65 - NCT07248956RecruitingPhase 2
Chemo plus immunotherapy before surgery for throat cancer
This trial tests giving chemotherapy combined with an immunotherapy drug (finotonlimab) before surgery for locally advanced hypopharyngeal cancer. It aims to shrink the tumor enough to improve surgery outcomes.
Harbin, HeilongjiangAges 18–75 - NCT07245030Recruiting
Virtual reality vs show-do for dental anxiety in kids with hearing loss
This trial tests whether virtual reality or a show-do method works better to reduce dental anxiety in children who have moderate to severe hearing loss. If your child needs a dental cleaning, this could help make the visit less stressful.
Giza, Giza GovernorateAges 6–12 - NCT05719207Recruiting
Balloon treatment for long-lasting clogged ear tube symptoms
This trial tests whether balloon dilation of the Eustachian tube can improve symptoms like ear pressure, muffled hearing, pain, ringing, and popping. It’s for people whose symptoms have lasted for months (or are triggered by pressure changes) and haven’t improved with usual non-surgical treatments.
Calgary, AlbertaAges 18 years+ - NCT06446713RecruitingPhase 1
Higher-dose proton therapy for advanced throat cancer
This trial is testing a higher, more precise dose of proton beam radiation for people with advanced throat cancer that is not connected to HPV. It aims to improve tumor control while protecting healthy tissue.
GroningenAges 18 years+ - NCT07238387Recruiting
AR glasses for testing eye movements in vertigo patients
This trial tests whether a pair of AR glasses can help doctors check eye movements (nystagmus) in people with vertigo or dizziness. You would compare the new glasses with standard testing, and it might be more comfortable and wearable.
Kaohsiung, TaiwanAges 18 years+ - NCT07236580Recruiting
Breathing exercises for teens with ear problems and smoke exposure
This study tests whether special breathing exercises can help teenagers with a blocked eustachian tube (the tube that connects the ear to the throat) whose parents smoke. It aims to improve ear and lung function.
Giza, DokkiAges 13–17 - NCT07237373Recruiting
Heat ablation for benign thyroid nodules
This trial tests a minimally invasive procedure called thermal ablation (using heat) to shrink benign thyroid nodules that cause symptoms like pressure or cosmetic issues, or overactive (hot) nodules. It offers an alternative to surgery or radioactive iodine.
BrugesAges 18 years+ - NCT07235488Recruiting
Integrative Medicine for Sudden Hearing Loss
This trial tests a combination of treatments (integrative medicine) for people who have just lost their hearing suddenly. It may help improve hearing recovery if started early.
TaichungAges 18 years+ - NCT07232680Recruiting
Immune profile study for nasopharyngeal cancer patients
This study looks at how the immune system responds to radiation therapy for nasopharyngeal cancer. It will use scans and blood tests to find markers that might predict how well treatment works.
Taoyuan City, TaiwanAges 18 years+ - NCT07228845Recruiting
Comparing 3D-printed vs. standard ear tips for hearing loss
This study tests whether a custom 3D-printed ear tip is more comfortable than a regular one for people with hearing loss. If you wear hearing aids or are considering them, this could help make the fit better.
Tucson, ArizonaAges 18–89 - NCT07225855Recruiting
Support for older adults with head and neck cancer and their caregivers
This trial tests whether a special geriatric assessment (a check-up for older adults) and extra support can help people aged 60+ with head and neck cancer feel better during chemotherapy and radiation. It also looks at how this helps their family or friend caregivers.
Duarte, CaliforniaAges 18 years+ - NCT07225023Recruiting
Physical therapy for dizziness in the ER
This trial tests whether having a physical therapist see you in the emergency room can help with dizziness. If successful, it could improve care for people with dizziness who go to the ER.
Chicago, IllinoisAges 18 years+ - NCT07226167Recruiting
Hearing aid benefit in noisy places
This study tests how well hearing aids help people hear in real-world noisy environments. If you already use hearing aids and have hearing loss in both ears that started after childhood, this trial may help understand how to improve your experience.
Madison, WisconsinAges 18 years+ - NCT07228104RecruitingPhase 3
Steroid treatment after surgery for idiopathic subglottic stenosis
This study tests whether giving steroids after a procedure to open your windpipe can reduce the chance that the narrowing comes back. If you have this condition, the trial is looking for people who are healthy enough to take part.
San Diego, CaliforniaAges 18–80 - NCT07222202Recruiting
Testing flexible hearing aids for hearing loss
This study tests flexible hearing aids for people with conductive or mixed hearing loss (where sound is blocked or not transmitted well to the inner ear). It aims to see if these devices work well and are comfortable for daily use.
Winston-Salem, North CarolinaAges 6 months–80 years - NCT07227792Recruiting
Tongue-out radiation therapy for head and neck cancer
This trial tests if sticking your tongue out during radiation therapy can reduce side effects. It is for people with certain types of head and neck cancer who are getting radiation to the main tumor.
Pittsburgh, PennsylvaniaAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.