Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT04506853Recruiting
Cochlear implant study for one-sided severe hearing loss
This trial is studying whether a cochlear implant can help people who have very poor hearing in one ear but normal or mild hearing loss in the other ear. It uses hearing tests and speech understanding to see who may benefit and how well the device works.
Chicago, IllinoisAges 5 years+ - NCT04544774Recruiting
Nasal allergen test to start and track allergy shots
This study uses a nasal allergen “provocation” test to help decide how to start and monitor allergy immunotherapy (allergy shots or drops). It may help doctors better track whether the treatment is working for people with allergic rhinitis.
Leuven, Vlaam BrabantAges 18–60 - NCT04544969Recruiting
Testing blood markers to guide chemo for metastatic nasopharyngeal cancer
This study looks at special blood markers (CTCs) to see how sensitive your cancer is to chemotherapy and to better predict how well treatment may work. If you have metastatic nasopharyngeal cancer and can’t have local treatment, this may help match you to more effective chemo plans.
Guangzhou, GuangdongAges 18–70 - NCT04547673Recruiting
Test an endoscopy camera tool to help diagnose throat cancer
This study checks an “intelligent” camera used during a nose-and-throat exam to improve how nasopharyngeal cancer is diagnosed. If you are eligible, your care team will compare how well the tool identifies the condition.
Guangzhou, GuangdongAges 18 years+ - NCT04591093Recruiting
Tested deep vs shallow sound settings in cochlear implants
This study looks at how changing the “stimulation depth” (how deep the sound signals are delivered in the implant) affects hearing performance in people with cochlear implants. It may help find the best settings for improving hearing outcomes for suitable adults.
ParisAges 18 years+ - NCT04602481Recruiting
Living with primary ciliary dyskinesia study
This study invites people who have been told they may have, or who have confirmed, primary ciliary dyskinesia. It aims to better understand living with PCD and what helps people day to day.
BernAges Any age - NCT04611516Recruiting
Study of ear, nose, and throat checks in PCD patients
This study follows people with primary ciliary dyskinesia (PCD) and looks at their regular ear, nose, and throat (ENT) checkups over time. Your participation may help doctors better understand how ENT care should be followed in PCD.
BernAges Any age - NCT04620343Recruiting
Study of breathing treatment for EILO during exercise
This trial tests a treatment approach for exercise-related breathing difficulty called EILO. It aims to help people whose breathing problems show up during peak exercise and who want ongoing follow-up.
Bergen, VestlandAges 12 years+ - NCT04645511Recruiting
Balloon treatment for long-term or repeat maxillary sinusitis
This study tests whether balloon sinuplasty works better or more efficiently for people with long-lasting or repeatedly returning inflammation in the maxillary sinuses (side sinuses near your cheeks). It focuses on people who did not improve with the usual nose spray (topical steroid) or who meet specific “recurrent” episode patterns.
TampereAges 18–69 - NCT04650919Recruiting
Rehabilitation graft after larynx removal for upper airway cancer
This trial tests a special “rehabilitation graft” used after total laryngectomy (complete larynx removal) for upper airway cancer. The goal is to improve recovery and function after surgery by using a graft designed to support healing and rehabilitation.
StrasbourgAges 18 years+ - NCT04665726Recruiting
Natural history study of Usher syndrome hearing and vision changes
This study follows people with Usher syndrome over time to better understand how hearing and vision symptoms change. It may help researchers measure disease progression and support future treatments.
ParisAges Any age - NCT04671381Recruiting
More affordable adult hearing care for eligible Alabama residents
This study aims to improve access and affordability of hearing healthcare for adults who have mild to moderate hearing loss. If you live in parts of South or West Central Alabama and meet the age and health requirements, your care may be coordinated through the program being tested.
Tuscaloosa, AlabamaAges 40 years+ - NCT04678167Recruiting
Special “ring” glasses for vestibular neuritis symptoms
This trial tests whether wearing “ring” glasses helps reduce symptoms from vestibular neuritis, a condition that causes spinning vertigo and balance problems. Participants may get the glasses being tested or look-alike placebo glasses (or not wear glasses), so the study can tell if the glasses truly help.
BrestAges 18 years+ - NCT04685746Recruiting
Testing how balance and motion affect child development
This study looks at how the vestibular system (your balance and motion sensing) is involved in children’s thinking and movement. It compares typically developing children with children who have balance-related (vestibular) problems or certain neurodevelopmental conditions to understand what to expect and how development may differ.
GhentAges 6–13 - NCT04696835Recruiting
Brain-light test with pediatric hearing aids
This study uses a special non-painful sensor test on the head (functional near-infrared spectroscopy, or fNIRS) to understand how young children’s brains respond while wearing hearing aids. It may help improve how hearing aids are adjusted for babies and toddlers with hearing differences.
LilleAges 3 months–1.5 years - NCT04706234Recruiting
Check swallowing and voice function in neurodegenerative diseases
This study looks at how well the throat and voice-related functions work in people with certain long-term brain or nerve conditions. It uses a specific throat exam during FEES to better understand swallowing and laryngopharyngeal (throat-area) function.
Innsbruck, TyrolAges 18 years+ - NCT04707885Recruiting
Testing how much residual hearing helps with cochlear implants
This study looks at whether keeping some natural (residual) hearing in the implant ear can improve outcomes with a cochlear implant. If you fit their hearing and implant-device requirements, they’ll measure your hearing before and after implantation to see how well you can use that remaining hearing.
Rochester, MinnesotaAges 18–79 - NCT04708717Recruiting
Testing brain training for people with cochlear implants
This study focuses on people who already use cochlear implants and tests a way to improve how the brain processes sound timing. If you’re an adult cochlear implant user, you may be able to join and help researchers understand what works best for hearing.
Los Angeles, CaliforniaAges 18 years+ - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT04733950Recruiting
Test how much effort listening takes with cochlear implants
This study measures how your brain and eyes respond when you listen and focus on sounds. It compares people using a cochlear implant with people who have normal hearing, to understand listening effort and attention.
ParisAges 18–80 - NCT04743609Recruiting
Studying RSV illness impact in babies with ear or lung symptoms
This study looks at how RSV (a common virus that can affect breathing) leads to illness in young children who come to the doctor with ear infections and/or breathing symptoms. It may help doctors better understand the “burden” RSV causes in both home/outpatient and hospital settings.
CréteilAges 1 day–2 years - NCT04778956RecruitingPhase 3
Toripalimab plus surgery vs surgery alone for recurring throat cancer
This trial tests whether adding toripalimab (an immune therapy) to surgery helps people with recurrent nasopharyngeal cancer live longer or control the cancer better than surgery alone. You may qualify if your recurrence can be fully removed by surgery and it came back after a certain amount of time.
Guangzhou, GuangdongAges 18–70 - NCT04782284Recruiting
Swallowing therapy for people with MSA and swallowing trouble
This study tests a comprehensive swallowing rehabilitation program for people with MSA (a nervous system condition) who have trouble swallowing. If you qualify, you may get structured swallowing therapy aimed at improving how safely you swallow.
SeoulAges 19 years+ - NCT04791748Recruiting
Virtual reality balance training for kids with inner-ear problems
This study uses virtual reality tasks to understand and compare balance and movement in children with long-term inner-ear (vestibular) problems versus those without. It may help doctors learn what supports best balance and safety during daily activities.
ParisAges 7 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.