Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07195734RecruitingPhase 2
Adding chemo or immunotherapy before surgery for advanced head and neck cancer
This trial tests whether giving chemotherapy or chemotherapy plus immunotherapy before surgery can improve outcomes for people with advanced head and neck cancer that has come back or not gone away after prior treatment.
Tucson, ArizonaAges 18 years+ - NCT06912698RecruitingPhase 3
Lower vs. standard radiation for early nasopharyngeal cancer
This trial compares a lower dose of radiation to the standard dose for people with early-stage nasopharyngeal cancer. It aims to see if a lower dose is just as effective while reducing side effects.
Guangzhou, GuangdongAges 18–70 - NCT07198568Recruiting
Swallowing and Neck Muscle Activity in Sarcopenic Dysphagia
This study looks at how the muscles in your neck and throat work when you swallow, specifically in older adults who have both sarcopenia (low muscle mass) and trouble swallowing. The goal is to better understand the connection between swallowing and muscle activity, which may help develop better treatments.
Incheon, Jung-guAges 65 years+ - NCT07195383Recruiting
Safe swallowing check after breathing tube removal in ICU
This study tests a special nutrition program for patients who just had a breathing tube removed in the ICU. It aims to see if a safe swallowing check can help prevent problems and make feeding safer.
IstanbulAges 18 years+ - NCT07193485Recruiting
Buteyko breathing for seniors with chronic ear tube blockage
This study tests whether a special breathing technique (Buteyko breathing) can help seniors with long-lasting Eustachian tube dysfunction that affects only one ear. It may offer a drug-free way to relieve ear pressure or discomfort.
Dokki, Giza GovernorateAges 65–75 - NCT04875611RecruitingPhase 2
Nivolumab for nasopharyngeal cancer after platinum chemotherapy
This trial studies nivolumab (an immune therapy) for nasopharyngeal cancer that grew or returned after platinum chemotherapy. It aims to shrink tumors or slow cancer growth after standard treatment hasn’t worked.
BialystokAges 18 years+ - NCT06670261Recruiting
Testing a new way to diagnose breathing problems
This study uses computer modeling to understand nasal breathing. It compares people without nasal symptoms and those with chronic nasal blockage from a deviated septum, to see if modeling can help diagnose the cause.
BordeauxAges 18–69 - NCT06942117Recruiting
Caffeine's effect on understanding speech in noise
This trial tests whether drinking caffeine helps young adults hear speech better in noisy places. If you have normal hearing, don't smoke, and don't have certain health issues, you might be able to join.
Istanbul, IstanbulAges 18–30 - NCT06944171Recruiting
How brain-related challenges affect daily life in children with cerebral palsy
This study looks at how impairments like muscle stiffness or weakness affect daily activities and participation in children (ages 6–12) with cerebral palsy. It could help families better understand their child's needs.
AnkaraAges 6–12 - NCT07183826Recruiting
Online mindfulness therapy for chronic tinnitus
This trial tests an online mindfulness program (iMBCT) to help people with chronic tinnitus manage their symptoms. If you have had tinnitus for at least 3 months and it bothers you, you may be able to join from home.
WarsawAges 18 years+ - NCT07184684RecruitingPhase 2/Phase 3
Nasal bacteria transplant for chronic sinusitis
This trial tests if transplanting healthy nasal bacteria from a donor can help people with chronic sinusitis. It aims to restore a healthy microbiome in the nose to reduce symptoms like congestion and discharge.
HelsingborgAges 18 years+ - NCT07185061Recruiting
Sound treatment for chronic tinnitus
This study tests whether a special sound-based treatment can help people with chronic tinnitus (ringing in the ears). If your tinnitus has lasted more than six months and you don't have other ear or brain problems, you may be able to join.
Nanjing, JiangsuAges 18 years+ - NCT07188584RecruitingPhase 3
Smaller radiation vs. standard after chemo-immunotherapy for advanced nasopharyngeal cancer
This trial tests whether a smaller radiation treatment area is as effective as the usual larger one for people whose metastatic nasopharyngeal cancer has responded well to first-line chemotherapy plus immunotherapy. It aims to reduce side effects while keeping the cancer under control.
ZhuhaiAges 18–70 - NCT07192757Recruiting
Trial to help you hear speech in noisy places
This study tests a new way to help people with age-related hearing loss understand conversations in noisy environments. It might improve your ability to hear clearly when there is background noise.
Gainesville, FloridaAges 55–80 - NCT07187583RecruitingPhase 4
Reducing biologic doses for chronic sinusitis with polyps
This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.
AalborgAges 18 years+ - NCT07184892Recruiting
Swallowing therapy after stroke
This study tests if watching swallowing movements (action observation therapy) helps people recover swallowing function after a first-time stroke. It uses a brain imaging technique called fNIRS to see how the brain responds.
Jinan, ShandongAges 18–80 - NCT06947161RecruitingEarly Phase 1
Throat pack with gum spray for sore throat after surgery
This study tests whether putting a throat pack soaked in a special gum spray (Gengigel) during surgery can help prevent sore throat afterward. It is for adults having planned surgery who are in good health.
Kuala LumpurAges 18–60 - NCT06939582RecruitingPhase 1/Phase 2
Hydroxychloroquine for radiation mouth sores
This trial tests if hydroxychloroquine tablets can prevent or reduce mouth sores caused by radiation therapy for head and neck cancer. If you are about to start radiation for head and neck cancer and have not had radiation before, this study might help manage painful mouth sores.
Chengdu, SichuanAges 18–80 - NCT07176533Recruiting
Nerve block for pain after tonsil surgery in kids
This study tests a nerve block (a numbing injection near the cheekbone) to reduce pain after tonsil surgery in children with sleep apnea. It might help them have less pain and recover more comfortably.
London, OntarioAges 3–9 - NCT07183670Enrolling by invitation
Testing a Voice Valve to Remove Breathing Tubes in Prolonged Consciousness Disorders
This study tests a new way to help people with long-lasting disorders of consciousness get their tracheostomy tube removed using a voice valve. If you qualify, this might help improve recovery and communication.
Beijing, Beijing MunicipalityAges 18–80 - NCT07176013Enrolling by invitation
Virtual reality meditation for voice therapy
This trial tests whether using virtual reality meditation can help people with voice disorders who also feel anxious. If you have a voice problem and anxiety, you might find this treatment helpful.
New York, New YorkAges 18 years+ - NCT07176936Recruiting
Can ear stimulation improve hearing in noise?
This study tests whether a gentle, noninvasive ear stimulation device can help people hear speech better in noisy places. It is for people who have had a traumatic brain injury or those with normal hearing.
Gainesville, FloridaAges 25–55 - NCT07178301RecruitingPhase 2
Lower radiation dose for HPV-related throat cancer
This trial tests whether a lower dose of radiation to the neck is safe and effective for people with HPV-related oropharyngeal cancer. It may reduce side effects while still treating the cancer.
Chicago, IllinoisAges 18 years+ - NCT07175779Recruiting
Comparing video calls vs. in-person visits for kids' surgery checkups
This trial tests whether a video call before surgery works as well as an in-person hospital visit for checking breathing risks in children getting their tonsils or adenoids removed. It may help families avoid extra trips to the hospital.
Bellinzona, Canton TicinoAges Up to 16 years
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.