Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06345560RecruitingPhase 1/Phase 2
Birth control pill study before and after weight-loss surgery
This study looks at how a progestin-only birth control pill works in obese women before and after bariatric surgery. It may help find the best way to prevent pregnancy during this time.
BangkokAges 18–45 - NCT06340685RecruitingPhase 1
Triheptanoin for children with PDC deficiency
This trial tests an oil called triheptanoin for children with a rare genetic condition (PDCD) that affects how their bodies use energy. The study aims to see if triheptanoin can help improve their health.
Pittsburgh, PennsylvaniaAges 1–17 - NCT06344143Recruiting
Detecting mild hormone overproduction from adrenal tumors
This study looks for a mild form of hormone overproduction (called autonomous cortisol secretion) in people who have a benign growth on their adrenal gland. You will undergo a blood test to measure how well your body suppresses cortisol after taking a single dose of dexamethasone.
Cleveland, OhioAges 18 years+ - NCT06345547Recruiting
Muscle mass ultrasound study in cirrhosis patients
This study uses ultrasound to measure muscle mass in people with cirrhosis. It aims to understand muscle changes and their link to health outcomes.
Edegem, AntwerpenAges 18 years+ - NCT06353646Recruiting
XH001 plus immunotherapy and chemotherapy after pancreatic cancer surgery
This trial studies a new treatment called XH001 combined with standard immunotherapy and chemotherapy for people whose pancreatic cancer has been surgically removed. The goal is to see if this combination helps prevent the cancer from coming back.
Beijing, Beijing MunicipalityAges 18–75 - NCT06338397Recruiting
Social and emotional thinking in Alzheimer's
This study looks at how Alzheimer's disease and similar conditions affect social and emotional thinking. Researchers will use brain scans and questionnaires to understand these changes better.
LilleAges 40–85 - NCT06345586Recruiting
Birth control pill study for women having weight-loss surgery
This study tests how a birth control pill with only drospirenone (a type of progestin) affects cervical mucus in women who are about to have weight-loss surgery. It will help understand if this pill is a good option for preventing pregnancy after surgery.
BangkokAges 18–45 - NCT06340217Recruiting
Washed Microbiota Transplant for Diabetic Stomach Paralysis
This trial tests a new treatment called washed microbiota transplantation for diabetic gastroparesis, a condition where the stomach empties slowly due to diabetes. If you have had diabetes for over a year and struggle with bloating or feeling full quickly, this study may explore whether transplanting healthy gut bacteria can help relieve your symptoms.
Nanjing, JiangsuAges 18–100 - NCT06358261Enrolling by invitation
Diabetes prevention study using a patient activation tool
This trial tests a tool that helps people with prediabetes take steps to prevent diabetes. If you are a patient at a specific Johns Hopkins clinic and use MyChart, you may be able to join.
Lutherville, MarylandAges 25–75 - NCT06343870RecruitingPhase 3
Hormone implants for menopause after cervical cancer or early menopause
This trial tests hormone implants (estradiol and testosterone) to treat menopause symptoms in women who have had their ovaries and uterus removed due to cervical cancer, or who have early menopause. The implants are placed under the skin and may help with hot flashes, mood, and sexual health.
São Paulo, São PauloAges 18–60 - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT06344507Recruiting
Registry of Pancreas and Bile Duct Endoscopy Procedures
This study collects pictures and information from people who have a routine endoscopic ultrasound to look at the pancreas and bile ducts. It aims to learn more about these conditions and improve future care.
MilanAges 18 years+ - NCT06356272Recruiting
Oropharynx cancer biomarker study
This study looks at certain markers (called p16 and HPV) in tumor samples to better understand oropharynx cancer. It may help doctors learn more about the disease and guide future treatments.
Rochester, MinnesotaAges 18 years+ - NCT06338553RecruitingEarly Phase 1
GLP-1 drug for early type 1 diabetes
This study tests whether a GLP-1 receptor agonist (a type of medicine that helps control blood sugar and appetite) can improve metabolic health in people with early type 1 diabetes. It may be an option if you have already taken teplizumab to delay the disease or were recently diagnosed with type 1 diabetes.
Nashville, TennesseeAges 12–50 - NCT06341179Recruiting
Does more sleep help children learn and manage weight?
This study tests whether helping children sleep longer each night can help them learn better and manage their weight. It is for children ages 6–12 who are above a healthy weight and sleep 9 hours or less per night.
CopenhagenAges 6–12 - NCT06355154Recruiting
Moderate carbohydrate diet for pregnant women with diabetes
This study tests whether eating a moderate amount of carbohydrates (carbs) can help control blood sugar and improve pregnancy outcomes in women with diabetes who use insulin. If you are pregnant with one baby and use insulin for diabetes, this trial may help you find a balanced diet approach.
JerusalemAges 18–45 - NCT06340945Recruiting
Treating benign thyroid nodules with heat
This study uses heat (thermal ablation) guided by ultrasound to shrink benign thyroid nodules that are causing symptoms or cosmetic concerns. It's an option if you can't have surgery or prefer not to.
BeijingAges 18 years+ - NCT04994665Recruiting
Test of fixing the stomach to reduce reflux after sleeve surgery
This study checks whether a surgical “fix” (omentumpexy) can reduce acid reflux after sleeve gastrectomy. It’s mainly for adults having sleeve surgery who have a higher-risk body weight and related health problems.
BayonneAges 18 years+ - NCT06325722Recruiting
Low fat vs. low carb diet order and body fat change
This study compares how the order of low fat versus low carb diets affects body fat changes. It may help you understand which diet sequence works best for weight loss.
Bethesda, MarylandAges 18–50 - NCT06322030Recruiting
Weight loss and exercise for stroke survivors
This study tests whether a weight loss and exercise program can help veterans who had a stroke at least 6 months ago and have some leg weakness. It aims to improve mobility and overall health.
Charleston, South CarolinaAges 40–80 - NCT06330064RecruitingPhase 1/Phase 2
Study of a new drug for advanced solid tumors
This study tests a new drug called Ifinatamab Deruxtecan (I-DXd) for people with several types of advanced cancer that has grown despite standard treatments. The drug is designed to target and attack cancer cells directly, potentially shrinking tumors or slowing their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT06328608RecruitingPhase 2/Phase 3
PRX-102 for children with Fabry disease
This study tests a new enzyme replacement therapy called PRX-102 for children with Fabry disease. It aims to see if the drug is safe and helps manage symptoms like pain and eye or skin changes.
Phoenix, ArizonaAges 2–17 - NCT06332807RecruitingPhase 1/Phase 2
Gene therapy trial for classic PKU
This trial tests a one-time gene therapy called NGGT002 for adults with classic PKU who cannot take or do not respond well to current treatments. The goal is to see if it can safely lower blood phenylalanine levels.
Orange, CaliforniaAges 18–55 - NCT06324604RecruitingPhase 1
Safety study of MTX-101 in healthy adults
This trial tests a new drug called MTX-101 in healthy volunteers to see if it is safe and how the body processes it. It helps determine the right dose before testing in patients with certain conditions.
Heidelberg, VictoriaAges 18–65
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.