Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,143
- Phase 21,065
- Phase 1821
- Phase 1/Phase 2445
- Phase 3424
- Phase 4238
- Phase 2/Phase 394
Top conditions
- Multiple Sclerosis341
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis141
- Type 1 Diabetes133
- Atopic Dermatitis128
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Acute Myeloid Leukemia62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals63
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland196
- Alabama175
- Florida143
- Arizona140
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06015542RecruitingPhase 2
Giving Elranatamab at Home for Relapsed Multiple Myeloma
This study tests if people with relapsed multiple myeloma can safely give themselves a medicine called elranatamab at home. It aims to make treatment more convenient while still being safe and effective.
OdenseAges 18 years+ - NCT06015880RecruitingPhase 1
Combination drug therapy for relapsed or resistant large B-cell lymphoma
This trial tests a combination of three drugs (mosunetuzumab, polatuzumab vedotin, and lenalidomide) for people with diffuse large B-cell lymphoma (a type of blood cancer) that has come back or not responded to previous treatment. The goal is to see if this combination is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT06016309Recruiting
Understanding Thinking, Energy, Mood, and Behavior in MS
This study looks at how multiple sclerosis affects thinking, energy, mood, and behavior. It uses simple tests and questionnaires to understand your unique profile, which may help tailor future care.
Groningen, Provincie GroningenAges 18–70 - NCT06018766RecruitingPhase 2
LAM-001 for lung transplant patients with BOS
This study tests whether the drug LAM-001 can help people who have developed a condition called bronchiolitis obliterans syndrome (BOS) after a double lung transplant. BOS causes a slow decline in lung function, and this trial aims to see if LAM-001 can slow or stop that decline.
San Francisco, CaliforniaAges 18 years+ - NCT06019975Recruiting
Using Brain PET Scans to Diagnose Autoimmune Encephalitis
This study uses a special brain scan (FDG-PET) to better understand autoimmune encephalitis, a condition where the immune system attacks the brain. It may help doctors improve diagnosis by comparing PET scan results with other tests you already had.
Udine, Friuli Venezia GiuliaAges Any age - NCT06021145RecruitingPhase 4
Adding empagliflozin to insulin pumps for type 1 diabetes
This study tests whether adding the diabetes pill empagliflozin (Jardiance) to your current automated insulin pump can help improve blood sugar control for adults with type 1 diabetes who are not reaching their glucose goals.
Montreal, QuebecAges 18 years+ - NCT06022939RecruitingPhase 3
Comparing chemo plus stem cell transplant to chemo alone for AL amyloidosis
This study tests whether adding a stem cell transplant to standard chemotherapy (Dara-VCD) works better than chemotherapy alone for people newly diagnosed with AL amyloidosis. It aims to find the best way to control the disease and improve outcomes.
Goodyear, ArizonaAges 18 years+ - NCT06022029RecruitingPhase 1
Study of injected ONM-501 alone or with cemiplimab for advanced cancers
This trial tests an injected study drug (ONM-501) alone or with another drug (cemiplimab) for people with advanced solid tumors or lymphomas that haven't responded to other treatments. It aims to find a safe dose and see if the combination helps shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06022549Recruiting
Mobile health for HIV patients with metabolic and bone issues
This trial tests a mobile health program designed to help people with HIV manage metabolic syndrome and bone loss. It aims to find if text messages and health tips can improve your health.
TaipeiAges 30 years+ - NCT06023056Recruiting
Hepatitis B vaccine after newborn surgery
This trial tests whether giving the hepatitis B vaccine to full-term newborns who had multiple stomach or intestine surgeries is safe and works well. It aims to protect these babies from hepatitis B infection.
Chongqing, Chongqing MunicipalityAges Any age - NCT06026488Recruiting
Study of DLBCL by genetic subtype
This study looks at how different genetic types of diffuse large B-cell lymphoma (DLBCL) respond to treatment in real-world settings. It may help doctors understand which treatments work best for your specific subtype.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06026319RecruitingPhase 1
CAR T cells targeting CD79b and CD19 for non-Hodgkin lymphoma
This trial tests a new type of CAR T-cell therapy that targets two proteins (CD79b and CD19) on lymphoma cells. It's for people with certain types of non-Hodgkin lymphoma that have come back or not responded to previous treatments.
Boston, MassachusettsAges 18 years+ - NCT06028087Recruiting
Blood Clot Prevention Study in Myeloma Patients
This study looks at how blood thinners are used in people with newly diagnosed multiple myeloma. The goal is to find better ways to prevent blood clots during treatment.
RomaAges 18 years+ - NCT06029309RecruitingPhase 1/Phase 2
Zanubrutinib and tafasitamab for mantle cell lymphoma
This trial tests two targeted drugs, zanubrutinib and tafasitamab, for people with mantle cell lymphoma. The goal is to see if this combination works better than standard treatments.
Miami, FloridaAges 18 years+ - NCT06032923RecruitingPhase 1/Phase 2
Does vitamin B3 boost help lupus symptoms?
This study tests whether a form of vitamin B3, called nicotinamide riboside, can improve immune function and reduce inflammation in women with mild to moderate lupus. It may help understand if boosting NAD+ levels offers a new way to manage the disease.
Bethesda, MarylandAges 18–120 - NCT06034275RecruitingPhase 1
Study of VIP943 for CD123-positive blood cancers
This trial tests a new drug called VIP943 for people with advanced acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), or myelodysplastic syndrome (MDS) whose cancer cells have a marker called CD123. It is for those who have tried all other treatments or cannot receive them.
Birmingham, AlabamaAges 18 years+ - NCT06034678Recruiting
Food allergy mastery program for teens and their families
This trial tests a program to help teens with food allergies learn more about managing their condition and reduce its impact on daily life. It is for kids ages 10–14 who have had a common food allergy for at least one year.
Washington D.C., District of ColumbiaAges 10–14 - NCT06034561RecruitingPhase 2
Bortezomib for relapsed or refractory acute lymphoblastic leukemia
This trial tests a chemotherapy combination that includes bortezomib for people whose acute lymphoblastic leukemia (ALL) has come back or not responded to previous treatments. It aims to offer a new option for those who haven't tried bortezomib before.
São Paulo, São PauloAges 16–60 - NCT06034938RecruitingPhase 2
Switching HIV Meds for People With M184V Mutation
This study tests switching your current HIV medicines to a once-daily pill combining doravirine, tenofovir, and lamivudine, specifically for people whose virus has a past M184V mutation but is now well controlled.
CaenAges 18 years+ - NCT06035289Recruiting
Severe asthma registry for children and adults
This registry collects information about children and adults with severe asthma that is not well controlled with standard treatments. The goal is to better understand severe asthma and improve care.
AltdorfAges 6 years+ - NCT06035328Recruiting
Comparing different maintenance doses for wheat allergy oral immunotherapy
This study tests whether taking a maintenance dose of wheat oral immunotherapy once or twice a week is more effective for children with wheat allergy. It aims to find the best schedule to keep them protected from allergic reactions.
Bangkoknoi, BangkokAges 5–18 - NCT06037018RecruitingPhase 1
Study of CC312 for B-cell blood cancers
This trial tests a new drug called CC312 for people with B-cell blood cancers that have come back or stopped responding to treatment. CC312 is designed to target CD19 on cancer cells, and the study checks if it is safe and how the body handles it.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06038019Recruiting
Food allergy threshold test and prediction study
This study looks at people with suspected or known food allergies to find out how much of a food it takes to cause a reaction. It uses an oral food challenge (eating the food under medical supervision) to predict your personal threshold.
Hamilton, OntarioAges 3 months–65 years - NCT06037967Recruiting
Studying biomarkers for allergies, asthma, and mast cell disorders
This trial collects blood and tissue samples to better understand allergies, asthma, and mast cell conditions. It aims to find markers that could improve diagnosis and treatment. Participation involves donating samples and sharing medical history.
ToulouseAges 18–100
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,742 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.