Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,064 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,060
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Myeloma328
- Multiple Sclerosis328
- Asthma194
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases78
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland199
- Alabama178
- Florida152
- Arizona149
- Massachusetts117
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,064 total
- NCT07030881Recruiting
Spacer use in older adults with COPD or asthma on triple therapy
This trial tests whether using a spacer with your inhaler can lower the risk of serious flare-ups for people over 65 who have COPD or asthma and are already on triple therapy.
Hefei, AnhuiAges 65 years+ - NCT07031063RecruitingPhase 4
HIV treatment study for people starting therapy
This study compares two HIV medications (DTG/3TC and BIC/TAF/FTC) to see which works better and is safer for people who have never taken HIV treatment before. It may help you find a once-daily pill that controls the virus and has fewer side effects.
Mexico City, AzcapotzalcoAges 18 years+ - NCT07024563RecruitingPhase 3
Testing ravulizumab for kids with IgA nephropathy
This study tests a drug called ravulizumab for children aged 2 to under 18 with IgA nephropathy, a kidney condition. It aims to see if the drug can help protect the kidneys and reduce protein in the urine.
Palo Alto, CaliforniaAges 2–18 - NCT07032662RecruitingPhase 2
Study of imeroprubart for chronic inflammatory demyelinating polyneuropathy (CIDP)
This trial tests whether a new medicine called imeroprubart can help people with CIDP, a nerve condition causing weakness and numbness. It may provide an alternative to current treatments like steroids or immunoglobulin therapy.
Tucson, ArizonaAges 18 years+ - NCT07024706RecruitingPhase 2
Study of acalabrutinib plus venetoclax for relapsed CLL
This trial tests a combination of two targeted drugs for people with CLL or SLL whose cancer returned after first treatment with a similar type of therapy. The goal is to see if this approach works well with a fixed treatment duration.
Boston, MassachusettsAges 18–130 - NCT07032246Enrolling by invitation
AI-assisted care for multiple sclerosis
This study uses artificial intelligence to help doctors better manage MS care. It uses MRI scans and a phone app to track your condition over time.
Prague, PragueAges 18 years+ - NCT07028970Recruiting
Long-term follow-up study for equecabtagene autoleucel recipients
This registry study will follow people who have received the CAR T-cell therapy equecabtagene autoleucel to monitor their long-term health and outcomes. It is open to those who completed or withdrew from an earlier study of this treatment.
BeijingAges Any age - NCT07029737RecruitingPhase 2
Studying acalabrutinib with R-CHOP for untreated mantle cell lymphoma
This trial tests adding acalabrutinib (a targeted therapy) to standard chemotherapy (R-CHOP) for people with mantle cell lymphoma who have not had treatment before and cannot have a stem cell transplant. The goal is to see if the combination works better than R-CHOP alone.
A CoruñaAges 18–130 - NCT06961669Recruiting
CD19 CAR-T cells for B-cell cancers and multiple myeloma
This trial tests a personalized treatment where your own immune cells are modified to target and kill cancer cells that have a protein called CD19. It is for patients with certain types of B-cell lymphoma, B-cell acute leukemia, or multiple myeloma that has come back or not responded to previous treatment.
HefeiAges 3 years+ - NCT06986278Recruiting
Treadmill training plus brain stimulation for multiple sclerosis
This trial combines treadmill training with a gentle brain stimulation technique (tDCS) to see if it can help people with Multiple Sclerosis walk better. The study is for people with stable MS and mild to moderate disability.
Toledo, ToledoAges 18 years+ - NCT06994403Recruiting
Pasta and blood sugar in type 1 diabetes
This study checks how eating a special carb-enriched pasta affects blood sugar in people with type 1 diabetes and compares it to healthy volunteers. It may help find better mealtime strategies for managing diabetes.
NaplesAges 18–50 - NCT07031102Recruiting
Methacholine challenge test for children with asthma
This study measures how children's airways respond to a substance called methacholine to understand how asthma affects lung function. It compares children with and without asthma to help improve diagnosis and treatment.
HelsinkiAges 7–15 - NCT07031713RecruitingPhase 1
Testing CT1192 cells for lupus that hasn't responded to treatment
This trial tests a new treatment called CT1192, which uses your own immune cells (T-cells) that are modified to target and calm overactive immune cells causing lupus. It is designed for people with moderate to severe lupus that hasn't improved with standard therapies like steroids, immunosuppressants, or biologics.
Wuhan, HubeiAges 18–60 - NCT07025538RecruitingPhase 1
Preventing chronic graft-versus-host disease with ruxolitinib
This trial tests whether the drug ruxolitinib, given based on a blood test that predicts risk, can prevent chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It may help people who have a higher risk of developing this complication.
Duarte, CaliforniaAges 18 years+ - NCT07030894RecruitingPhase 4
Study of Nefecon and Ambrisentan for IgA Nephropathy
This trial tests two medications, Nefecon and Ambrisentan, to see if they can help people with IgA nephropathy, a kidney disease. It may be an option if you have been diagnosed with IgA nephropathy in the last 4 years and have protein in your urine.
Changchun, JilinAges 18–70 - NCT07032714RecruitingPhase 1
Mezigdomide and talquetamab for relapsed multiple myeloma
This trial tests a combination of two drugs, mezigdomide (a pill) and talquetamab (an injection), for people with multiple myeloma that has come back or not responded to at least three prior treatments. The goal is to see if this combination can help control the disease.
Boston, MassachusettsAges 18 years+ - NCT07029958RecruitingPhase 4
Transplant protocol for EBV-related T/NK lymphoproliferative disease
This trial tests a stronger transplant conditioning regimen to treat a rare immune disorder caused by the Epstein-Barr virus. It aims to improve outcomes and reduce a complication called graft-versus-host disease, where donor cells attack the patient's body.
BeijingAges birth–18 years - NCT07033858Recruiting
Short-term effects of Advograf plus Rapamiune after kidney transplant
This trial tests a combination of two medications (Advograf and Rapamiune) given shortly after kidney transplant to see how well they work and how safe they are. It may help improve long-term transplant health.
TehranAges 18 years+ - NCT07025200Recruiting
Severe asthma study using bronchoscopy to check treatment
This study tests a new way to monitor severe asthma that is driven by high levels of inflammation (T2-high). It involves a bronchoscopy (a thin tube to look inside your lungs) to see how well the treatment is working.
Vienna, State of ViennaAges 18 years+ - NCT07032103Recruiting
Lymphoma study tracking patient outcomes over time
This study follows people with Hodgkin or non-Hodgkin lymphoma who need strong treatment to try to cure their cancer. The goal is to learn more about how the disease and its treatment affect patients over time.
SeoulAges Any age - NCT07030400Recruiting
Quality of life study for adults with CLL or SLL
This study looks at how health-related quality of life changes in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) when starting a new treatment. The goal is to better understand what affects well-being during therapy.
Tampa, FloridaAges 18 years+ - NCT07029386Recruiting
Brain stimulation for thinking problems in MS and NMOSD
This trial tests a gentle brain stimulation technique (transcranial electrical stimulation) to see if it can improve thinking and memory problems in people with inflammatory brain diseases like MS or NMOSD. It may help if you feel your thinking has slowed down.
BeijingAges 18–65 - NCT07033663Recruiting
Monoclonal antibody exposure during pregnancy and baby's immune system
This study looks at how monoclonal antibody treatments given during pregnancy affect a baby's immune system development. It compares babies whose mothers received these treatments throughout pregnancy, only in early pregnancy, or not at all.
Esplugues de Llobregat, BarcelonaAges Any age - NCT07032129RecruitingPhase 1/Phase 2
Targeted cell therapy for multiple myeloma that returned or didn't respond
This trial tests a new type of treatment using your own immune cells (called CAR-T cells) that target two proteins on myeloma cells: BCMA and GPRC5D. It's for people whose myeloma has come back or stopped responding to standard treatments, and who may have few other options left.
Beijing, Beijing MunicipalityAges 21–90
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,064 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,178 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.