Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,064 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,060
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Myeloma328
- Multiple Sclerosis328
- Asthma194
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases78
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland199
- Alabama178
- Florida152
- Arizona149
- Massachusetts117
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,064 total
- NCT07043946RecruitingPhase 1/Phase 2
Budoprutug for immune thrombocytopenia
This trial tests a new drug called budoprutug for people with immune thrombocytopenia (ITP), a condition where your immune system attacks your own platelets, causing low counts. The study aims to see if the drug can safely raise platelet levels and reduce bleeding risk.
PlovdivAges 18 years+ - NCT07039578RecruitingPhase 2
Study of CM336 for light-chain amyloidosis
This trial tests a new injection called CM336 for people with light-chain amyloidosis that has come back or not responded to other treatments. It aims to see if the drug is safe and effective.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06991881Recruiting
Better management for eosinophilic esophagitis
This study looks at how to improve care for people with eosinophilic esophagitis (EoE), a condition that causes inflammation in the esophagus. It may help you if you have or are being checked for EoE.
BergenAges Up to 17 years - NCT07039474Recruiting
New PET scan to monitor cancer immunotherapy response
This trial tests a special PET scan that tracks immune activity to see if it can help monitor how well immunotherapy is working in people with various cancers. It is for patients about to start immunotherapy for the first time.
BeijingAges 18–75 - NCT07034196Recruiting
Comparing RA care: primary care vs. rheumatologist
This study compares RA care from your primary care doctor (with extra training) to care from a rheumatologist. It's for people with stable RA living in northern New York who want to see if primary care can work as well as a specialist.
Potsdam, New YorkAges 18 years+ - NCT07037511Recruiting
Salbutamol in endurance athletes: a screening study
This trial tests how the asthma medication salbutamol affects endurance athletes. If you are a healthy athlete in running or cycling, your data may help improve sports safety.
Vancouver, British ColumbiaAges 18–55 - NCT07040774Recruiting
Study of type 1 interferonopathies in Europe
This study looks at people with a confirmed type 1 interferonopathy, a rare immune condition caused by a gene change. It aims to learn more about how the condition progresses over time.
InnsbruckAges Any age - NCT07037043RecruitingPhase 3
Steroid medicines for high-risk heart surgery patients
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
AmiensAges 18 years+ - NCT07038642Enrolling by invitation
Asthma Management System Test in Pharmacies
This study tests an electronic system to help manage asthma in pharmacies. It looks at how the system can improve care for people with asthma and support pharmacy staff.
Ajax, OntarioAges 16 years+ - NCT07038746RecruitingPhase 1
Inhaled epinephrine for severe allergic reactions during tests or treatment
This trial tests if inhaled epinephrine can safely treat moderate to severe allergic reactions (grade 2 or higher) that can happen during allergy skin tests, oral food or drug challenges, or allergy shots. It is for people who have had such reactions in the past or are at risk and are planning to undergo one of these procedures.
Richmond, British ColumbiaAges 12 years+ - NCT07040189Recruiting
AI nutritional plan for taste changes from chemo
This study tests an AI-created diet plan to help with taste problems caused by chemotherapy. It may help manage taste issues by suggesting recipes tailored to you.
Munich, BavariaAges 18 years+ - NCT07044427Recruiting
Fall prevention exercise for multiple myeloma patients
This trial tests if a home exercise program can help prevent falls in people with multiple myeloma. It is for patients who are currently receiving or have recently received cancer therapy and want to exercise at least three times a week.
Heidelberg, Baden WürtembergAges 18 years+ - NCT07042438RecruitingPhase 2
Fecal transplant to improve CAR T therapy for lymphoma
This study tests whether a fecal transplant (transferring healthy gut bacteria) can improve outcomes for people with certain lymphomas who have taken strong antibiotics and are about to get CAR T-cell therapy (Yescarta). The goal is to see if rebuilding gut bacteria helps the treatment work better.
Duarte, CaliforniaAges 18 years+ - NCT07037810Enrolling by invitation
Comparing two ways to match insulin to meals in type 1 diabetes
This study tests two methods for deciding how much insulin to take with meals: counting exact carbohydrates or using a simpler meal-size guide. It aims to see which approach works best for people with type 1 diabetes who already use multiple daily injections and have moderate to high blood sugar levels (HbA1c 7.5% to under 11%).
Kuwait CityAges 21 years+ - NCT07033975Recruiting
Specialized diet for multiple sclerosis
This trial is testing a specialized diet for people with multiple sclerosis (MS) who are not too severely disabled. You may be able to join if you have mild to moderate MS and do not have a diagnosed digestive disorder.
Diepenbeek, LimburgAges 30–65 - NCT07041268RecruitingPhase 2
Rituximab for recent type 1 diabetes in teens
This trial tests if repeated infusions of rituximab (a drug that calms the immune system) can help preserve insulin production in adolescents newly diagnosed with type 1 diabetes. It is for teens in Russia who started diabetes treatment within the last 4 months.
MoscowAges 12–18 - NCT07040332Recruiting
Understanding allergic bronchopulmonary aspergillosis
This study looks at why some people with asthma get a lung infection from mold called aspergillus. It will help doctors better understand the condition and how to treat it.
Jinan, ShandongAges 18 years+ - NCT07040306Recruiting
Follow-up study on drug therapy for Graves' disease
This study looks at how well medication works for people with Graves' disease in China. It may help doctors understand the best treatment options for both new cases and relapses.
Shenyang, LiaoningAges 18 years+ - NCT07043153Recruiting
Predicting lupus disease activity with blood tests
This study looks at whether two blood markers (AGR and PNI) can help track how active lupus is. You may be eligible if you have lupus and are not pregnant or have other serious health conditions.
SohagAges 18 years+ - NCT03937544RecruitingPhase 2/Phase 3
Study of your own CAR-T cells for hard-to-treat B-ALL
This trial tests a treatment made from your own immune cells (CAR-T cells) to help control relapsed or refractory B-ALL. It is designed for people whose disease has come back or not responded to prior therapy, and who have specific brain/spinal fluid and organ health requirements.
Bandar Tun Razak, Kuala LumpurAges 13–65 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT04898647Recruiting
Study of blood thickness in Waldenström’s disease
This study looks at “hyperviscosity,” meaning very thick blood, in people with Waldenström macroglobulinemia (WM). Your results may help doctors better understand who needs treatment and what tests should be used, even if thick blood is not found.
AmiensAges 18 years+ - NCT06710717RecruitingPhase 1
CD19 CAR T-cells for severe lupus
This early-phase trial tests whether a patient's own immune cells (T-cells) that are modified to target a protein called CD19 can help people with severe lupus that hasn't improved with other treatments. The goal is to reduce lupus activity and possibly achieve remission.
Bandar Tun Razak, Kuala LumpurAges 18–65 - NCT06389994Recruiting
String test to monitor esophagus health during allergy treatment
This study tests a new way to check for a condition called eosinophilic esophagitis (EoE) in children getting oral immunotherapy for food allergies. You swallow a small capsule on a string to collect cells from your esophagus—no endoscopy needed.
Philadelphia, PennsylvaniaAges 7–17
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,064 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,178 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.