Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06264258Recruiting
Game-based diabetes education for kids
This study tests a fun video game to help children aged 6–12 with type 1 diabetes learn about managing their condition. It may improve how kids check their blood sugar and take insulin.
Pittsburgh, PennsylvaniaAges 6–12 - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+ - NCT06267781Recruiting
MS progression and immune cells after bone marrow transplant and other therapies
This study looks at how well different treatments, including bone marrow transplant, alemtuzumab, ocrelizumab, and ofatumumab, work for people with relapsing-remitting MS who have active disease. It will help doctors understand which therapy might slow disease progression best.
MilanAges 18 years+ - NCT06270888RecruitingPhase 1
Shorter radiation treatment for multiple myeloma
This trial tests a shorter course of radiation therapy for up to 5 bone lesions that have come back or not responded to treatment. It aims to see if this approach is safe and helps control the disease.
Chicago, IllinoisAges 18 years+ - NCT06270641Recruiting
Increasing physical activity for adults with MS
This study tests whether using a phone app (ExerciseRx) can help people with multiple sclerosis become more active. You may be able to join if you are not currently very active and can walk without needing a cane or walker.
Seattle, WashingtonAges 18 years+ - NCT06270667Recruiting
Exercise training for lymphoma survivors
This study tests whether a supervised exercise program can improve heart health in people who finished treatment for Hodgkin or aggressive non-Hodgkin lymphoma 2–5 years ago. The goal is to see if regular exercise helps your heart recover better after chemotherapy or chest radiation.
OsloAges 20–70 - NCT06271018Recruiting
Tocilizumab for Aortitis in Giant Cell Arteritis
This trial tests the drug tocilizumab (Actemra) to see if it helps reduce swelling in the aorta in people with giant cell arteritis (GCA) who are newly diagnosed or have had a flare. It may offer a targeted treatment for aortitis without using high-dose steroids.
ParisAges 18 years+ - NCT06271252RecruitingPhase 1
Study of OriCAR-017 for relapsed or refractory multiple myeloma
This trial tests a new type of CAR-T cell therapy called OriCAR-017 for people with multiple myeloma that has come back or not responded to treatment. It is for patients who have already tried several treatments, including ones that target BCMA, and their last treatment stopped working.
Atlanta, GeorgiaAges 18–75 - NCT06272084Recruiting
Review of plasmapheresis treatments (TPE) using multiFiltratePRO
This study looks back at the medical records of people who had plasmapheresis (TPE) treatment to learn more about how it works. If you had this treatment between 2019 and 2023, researchers may use your data.
Aschaffenburg, BavariaAges 18 years+ - NCT06272136Recruiting
Non-invasive continuous glucose monitor study for diabetes
This trial tests a new non-invasive continuous glucose monitor that you wear on your wrist like a watch, without needing finger sticks. It is designed for people with type 1 or type 2 diabetes who use insulin or certain diabetes pills.
Neuss, Nordrhein-WestfallenAges 18–65 - NCT06273072RecruitingPhase 2
Metformin for asthma in overweight adults
This trial tests whether the diabetes drug metformin can help people with asthma who are also overweight or obese. The goal is to see if it improves asthma control and reduces the need for rescue medications.
Baltimore, MarylandAges 18 years+ - NCT06273631Recruiting
Carbohydrate intake changes and blood sugar in type 1 diabetes
This trial looks at how changing the amount of carbohydrates you eat affects blood sugar control. It aims to find better ways to manage diabetes through diet.
Nanjing, JiangsuAges 18–70 - NCT06274632Recruiting
Helping Latinos with HIV stay engaged in care
This study tests a program to help Latino adults with HIV who are not yet virally suppressed stay connected to their healthcare. It aims to improve engagement in care and reduce the virus in the body.
Miami, FloridaAges 18 years+ - NCT06275412Recruiting
Family program for Black teens with type 1 diabetes
This study tests a family-based program to help Black teens with type 1 diabetes manage their condition. You and your child would work together with a coach to build skills and support.
Washington D.C., District of ColumbiaAges 10–14 - NCT06275373Recruiting
Teprotumumab for thyroid eye disease study
This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).
Bethesda, MarylandAges 18 years+ - NCT06276634Recruiting
Low-Oxygen Therapy for People With Multiple Sclerosis
This study tests whether brief, controlled low-oxygen episodes (called intermittent hypoxia) can improve motor function in people with MS. It may help strengthen walking and daily movement.
Chicago, IllinoisAges 18–75 - NCT06277427Recruiting
CAR-T cell therapy for refractory vasculitis and lupus nephritis
This trial tests a new type of cell therapy called CAR-T cells that target BCMA (a protein on certain immune cells) for people with two autoimmune diseases: ANCA-associated vasculitis and lupus nephritis. It is for patients whose disease has not responded to standard treatments or has come back after initial improvement.
Wuhan, HubeiAges 18–70 - NCT06278337Recruiting
Moesin-associated immunodeficiency study
This study looks at a rare immune system condition caused by changes in the MOESIN gene. It aims to better understand the condition and may help develop future treatments.
Bethesda, MarylandAges 4–80 - NCT06278662Recruiting
Asthma treatment study for children 4 to 18 years old
This trial tests different ways to manage asthma in children. It aims to see which treatment approach works best for your child's symptoms and lung function.
Enschede, OverijsselAges 4–18 - NCT06279026Recruiting
Testing UTAA17 for advanced multiple myeloma
This trial tests a new treatment called UTAA17 that targets a protein on myeloma cells. It may be an option for people whose multiple myeloma has not responded to several prior treatments.
Suzhou, JiangsuAges 18 years+ - NCT06279065Recruiting
Gut bacteria and giant cell arteritis study
This trial looks at how the bacteria in your gut might affect giant cell arteritis, a condition that causes inflammation in blood vessels. It aims to help doctors better understand the disease.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06279923RecruitingEarly Phase 1
CAR-T cells for autoimmune diseases
This trial tests a new CAR-T cell therapy that targets two immune proteins (CD19 and BAFF) to treat autoimmune diseases like lupus or scleroderma. It is for people who have not improved with standard treatments.
Hangzhou, ZhejiangAges 18 years+ - NCT06279676Recruiting
Improving women's health after donor stem cell transplant
This study looks at improving health after a stem cell transplant from a donor. It focuses on women's health issues after the transplant.
Montreal, QuebecAges 18 years+ - NCT06280703RecruitingPhase 1
Study of LY3938577 for type 1 diabetes
This study tests an investigational drug called LY3938577 in healthy people and people with type 1 diabetes. It looks at how the drug affects the body and whether it might help control blood sugar.
NeussAges 18–64
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.