Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT07678931RecruitingPhase 3
New injection for seasonal allergies in teens
This trial tests a new biologic medicine (injection) to see if it can better control seasonal allergy symptoms in teens who haven't had good relief from standard treatments like nasal sprays.
Beijing, Beijing MunicipalityAges 12–18 - NCT07673744RecruitingPhase 2
Maintenance treatment for myasthenia gravis after efgartigimod
This trial tests whether a follow-up treatment with ublituximab (given as an infusion) can help myasthenia gravis patients who first received efgartigimod. The goal is to see if it provides lasting control of MG symptoms.
Colorado Springs, ColoradoAges 18 years+ - NCT07677059RecruitingPhase 2
Long-term study of KT-621 for asthma patients from previous study
This trial is for people with asthma who already completed a previous study of the drug KT-621. It aims to see if taking KT-621 for a longer time is safe and helpful.
Miami, FloridaAges 18 years+ - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07679412Recruiting
CMV Retinitis Trial: Your Own Cells vs. Resistant Virus
This trial tests a new treatment made from your own immune cells (called LB-DTK-CMV) for a type of CMV eye infection that is not getting better with standard antiviral drugs. The goal is to see if these cells can safely control the infection and improve your vision.
SeoulAges 19 years+ - NCT07675811RecruitingPhase 3
Study of a new treatment for cat allergy related eye symptoms
This trial tests an injectable treatment that may help manage eye allergy symptoms caused by cat allergies. It aims to see if the treatment is safe and effective for adults and children, and includes a controlled cat exposure challenge.
Andover, MassachusettsAges 8 years+ - NCT07678034Recruiting
Long-term safety study of Tipmed shoulder replacement system
This study checks how safe and effective the Tipmed shoulder replacement system is over time. It is for people who already had this specific shoulder implant during surgery.
BalıkesirAges 18 years+ - NCT07672522Recruiting
Infections and the aging immune system in older adults
This study is looking at how infections and the aging immune system affect older adults. It compares people with an infection to healthy volunteers to understand how the body fights germs as we age.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT07679776Enrolling by invitation
Study on early vision changes in lupus patients
This study looks at whether people with systemic lupus erythematosus (SLE) have early signs of vision problems. Eye tests will be used to check how well you see and if there are any hidden issues in your eyes.
Hefei, AnhuiAges Any age - NCT07679321Recruiting
Anxiety & depression's effect on asthma control
This study looks at how anxiety and depression affect how well asthma medications work. It aims to help predict who might have an asthma attack, so doctors can treat you better.
Changsha, HunanAges 14 years+ - NCT07674498Recruiting
Immune health in older adults with advanced myeloma
This trial studies the immune system of adults 65 and older with multiple myeloma that has come back or not responded to treatment. It looks at how their immune fitness may affect their ability to receive newer therapies like CAR-T cells or bispecific antibodies.
Anderlecht, Brussels CapitalAges 65 years+ - NCT07674134Recruiting
A Study of a JAK Inhibitor Pill for Rheumatoid Arthritis
This trial tests taking a JAK inhibitor (a type of pill that helps calm inflammation in rheumatoid arthritis) by mouth. It aims to see how well it works and if it's safe for people with RA who need this kind of medicine.
MonacoAges 18 years+ - NCT07673354Enrolling by invitation
Spinal cord stimulation at home for hand and arm function in MS
This trial tests if gentle electrical stimulation can help improve hand and arm function in people with multiple sclerosis. You will use a small device at home with support from a caregiver.
Seattle, WashingtonAges 18–70 - NCT07678112Recruiting
Trial of a device to keep rheumatoid arthritis in remission
This trial tests a medical device to help people with rheumatoid arthritis stay in remission while on biologic therapy. The goal is to see if the device can prevent flares and maintain disease control.
A Coruña, A CoruñaAges 18 years+ - NCT07673367RecruitingPhase 2
Nemtabrutinib with CAR T for relapsed mantle cell lymphoma
This trial tests adding a targeted pill (nemtabrutinib) to standard CAR T-cell therapy for people with mantle cell lymphoma that has come back or not responded to treatment. The goal is to see if this combination works better than CAR T alone.
Nashville, TennesseeAges 18 years+ - NCT07676877RecruitingPhase 1
Low-dose radiation before CAR-T therapy for large B-cell lymphoma
This trial adds a small, whole-body dose of radiation to the standard preparation before CAR-T cell therapy (tisagenlecleucel). The goal is to improve the treatment's effectiveness for patients with relapsed or refractory large B-cell lymphoma.
Columbus, OhioAges 18 years+ - NCT05602376Recruiting
HIV messages to help men get tested and stay in care
This study tests whether special “U=U” style messages can improve how men move from HIV testing to starting treatment and continuing care. You may be asked to receive guidance and information meant to help you stay engaged in HIV treatment.
East London, Eastern CapeAges 15 years+ - NCT06656299Recruiting
Nerve block for gallbladder removal surgery
This study tests a nerve block called EOIB to see if it helps reduce pain after gallbladder removal surgery. If you are having planned gallbladder surgery, this might be a good option for you.
IstanbulAges 18–65 - NCT06665607Recruiting
Foot muscle training for people with MS
This study tests whether training the small muscles in your feet can improve your walking and balance if you have multiple sclerosis (MS). It is for people with moderate disability, so you can still walk but may have some trouble.
ValladolidAges 18–70 - NCT06608732RecruitingPhase 2
CAR-T therapy plus stem cell transplant for B-cell ALL with MRD
This trial tests a combination of a CAR-T cell therapy (Inaticabtagene Autoleucel) followed by your own stem cells being transplanted back into you. It is for teenagers and adults who have B-cell acute lymphoblastic leukemia (ALL) that is in first complete remission but still has tiny amounts of cancer cells (called MRD) that can be detected by sensitive tests.
Tianjin, Tianjin MunicipalityAges 16–70 - NCT06428188RecruitingPhase 1/Phase 2
CAR-T cells targeting BCMA/CD19 for autoimmune diseases
This trial tests a new treatment called CAR-T cells that target two proteins (BCMA and CD19) on immune cells. It is for people with certain autoimmune diseases that have not improved with standard treatments.
Beijing, Beijing MunicipalityAges 21–90 - NCT07664228Recruiting
Predicting stomach pain in children with IgA vasculitis
This study looks at a blood test done when a child is first diagnosed with IgA vasculitis (also called Henoch-Schönlein purpura) to see if it can predict stomach or intestine problems. It involves one extra blood draw at diagnosis and a follow-up visit a few weeks later.
Bursa, BursaAges 2–18 - NCT07666490RecruitingPhase 4
Triple vs double inhaler for uncontrolled asthma
This study compares a three-in-one inhaler (ICS/LABA/LAMA) to a two-in-one inhaler (ICS/LABA) for adults whose asthma is not well-controlled despite using a standard two-in-one inhaler. The goal is to see if the triple inhaler improves asthma control better.
RousseAges 18 years+ - NCT07665723RecruitingPhase 1
Study of afimkibart and other medicines in ulcerative colitis
This study looks at how afimkibart affects the way your body processes certain other medicines. It is for people with moderate to severe ulcerative colitis and helps researchers understand how to use this treatment safely.
Chula Vista, CaliforniaAges 18–60
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.