Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT07665450RecruitingPhase 3
Ramantamig plus daratumumab for untreated multiple myeloma without stem cell transplant
This trial tests a new combination of two drugs, ramantamig and daratumumab, against other standard treatments for people newly diagnosed with multiple myeloma who are not planning to have a stem cell transplant. The goal is to see if this combination works better at controlling the cancer.
NantesAges 18 years+ - NCT07671001RecruitingPhase 3
Study of depemokimab for children (6-11) with asthma
This trial tests if a new medicine, depemokimab, can help children aged 6 to 11 whose asthma is not well controlled with their current inhalers and who have a type of inflammation called eosinophilic asthma. It may reduce asthma attacks and improve symptoms.
Mobile, AlabamaAges 6–11 - NCT06675422RecruitingPhase 1/Phase 2
JY231 injection for active lupus
This trial tests an investigational drug called JY231 for people with active systemic lupus erythematosus (SLE) that is not well controlled with standard treatments. The goal is to see if JY231 can reduce lupus activity and improve symptoms.
Kunming, YunnanAges 14–75 - NCT07663422RecruitingPhase 2
Treating immunotherapy-related liver inflammation with mycophenolate and prednisone
This trial tests a combination of two drugs, mycophenolate mofetil and prednisone, to treat moderate to severe liver inflammation caused by immunotherapy. The goal is to see if this treatment can help control the inflammation without needing long-term high-dose steroids.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07665307Recruiting
Delayed side effects after CAR-T for multiple myeloma
This study looks at late side effects that may happen after CAR-T therapy (cilta-cel) for multiple myeloma. It aims to better understand these delayed toxicities so doctors can manage them more effectively.
San Francisco, CaliforniaAges 18 years+ - NCT07671378RecruitingPhase 2
Study of zanubrutinib plus sonrotoclax for high-risk CLL/SLL
This trial tests a combination of two targeted drugs (zanubrutinib and sonrotoclax) as a first treatment for people with high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL). It aims to see if this approach works better than standard care by using a test called MRD to guide treatment duration.
Nanjing, JiangsuAges 18–75 - NCT07670572Recruiting
Think-find-solve activities for type 1 diabetes in children
This study tests fun puzzle-like activities called Think-Find-Solve to help children with type 1 diabetes learn to manage their own insulin. It aims to make diabetes care easier and more independent for kids, with support from a parent.
IstanbulAges 8–12 - NCT07666711Recruiting
Kidney biomarker study for lupus patients
This study aims to find better ways to detect kidney problems in people with lupus by testing blood and urine samples. If you have lupus, you may help researchers improve how kidney disease is diagnosed and monitored.
Oslo, OsloAges 18 years+ - NCT07667504Recruiting
Dietary approaches for weight management in type 1 diabetes
This study tests two different diet approaches to help people with type 1 diabetes who are overweight or obese manage their weight. It aims to find out which eating plan works better for blood sugar control and weight loss.
Málaga, MálagaAges 18–65 - NCT07666789Recruiting
Second Islet Transplant for type 1 diabetes
This study looks at how well a second islet transplant works in people with type 1 diabetes whose first transplant stopped producing insulin or caused dangerous low blood sugar. It aims to see if getting another transplant can help control blood sugar again.
MontpellierAges 18 years+ - NCT07663669Recruiting
Photopheresis for antibody-mediated rejection in kidney transplant
This study looks at how well extracorporeal photopheresis (a treatment that filters and treats your blood with light) works for kidney transplant patients who have antibody-mediated rejection (when your immune system attacks the new kidney). It may help doctors understand if this treatment can stop the rejection.
BesançonAges 18 years+ - NCT07668596Recruiting
Broccoli sprout supplement and exercise in healthy adults
This trial studies how a natural compound from broccoli sprouts (sulforaphane) and exercise, alone or together, affect your body's immune and metabolic health. It's for healthy, active adults aged 19–35.
Kelowna, British ColumbiaAges 19–35 - NCT07664709Recruiting
Eye problems in granulomatosis with polyangiitis study
This study looks at eye problems in people who have a disease called granulomatosis with polyangiitis (GPA), which is a type of blood vessel inflammation that can also affect the eyes. They want to understand what eye issues happen in this disease.
WarsawAges 18 years+ - NCT06676410RecruitingPhase 2
Testing Codivir plus standard HIV treatment in new patients
This trial tests a new investigational drug called Codivir added to standard HIV treatment for people who have never taken HIV medications before. It aims to see if adding Codivir helps control the virus better and is safe.
São PauloAges 18 years+ - NCT04763447RecruitingPhase 4
Short omalizumab treatment for severe allergic asthma
This trial tests whether stopping omalizumab for a short time (or using it differently) can be safe for adults with severe allergic asthma who are doing well. It may help some people avoid long-term injections, but only if asthma remains well controlled.
Paris, Île-de-France RegionAges 18 years+ - NCT06480604Recruiting
Probiotic for yeast infection prevention
This trial tests if taking a multi-strain probiotic daily can prevent repeat yeast infections in women who have had at least three infections in the past year.
Vadodara, GujaratAges 18–50 - NCT06463119Recruiting
Vaccine response registry for immune-weakened patients
This study creates a registry to track how people with weakened immune systems respond to vaccines. It helps doctors better understand which vaccines work best for patients like you.
GenevaAges Any age - NCT07661537RecruitingPhase 1
Study of SHR-3079 for B-cell Non-Hodgkin Lymphoma
This trial tests a new drug called SHR-3079 for people with B-cell non-Hodgkin lymphoma whose cancer did not get better or came back after at least one standard treatment. The goal is to see if the drug can help shrink tumors or slow the disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07663409Recruiting
Studying markers in sinusitis patients having surgery
This study looks at tissue and blood samples from people with chronic sinusitis to find markers that could predict how the disease behaves. It may help doctors choose better treatments in the future.
AlexandroupoliAges 18 years+ - NCT07660835RecruitingPhase 2
A study of nemolizumab for babies with eczema
This trial tests a medicine called nemolizumab for babies aged 6 to 23 months with moderate to severe eczema. The goal is to see if it reduces itching and improves skin symptoms.
San Antonio, TexasAges 6 months–1.9 years - NCT07661056RecruitingPhase 3
Investigational drug for treating graves' disease overactive thyroid
This study tests a new medicine, BHV-1300, to see if it can safely and effectively reduce the overactive thyroid caused by Graves' disease, an autoimmune condition. It may offer a new option for people who haven't had certain prior treatments.
Tucson, ArizonaAges 18–70 - NCT07660731RecruitingPhase 1
Safety study of an experimental asthma medicine
This study tests an experimental medicine (PF-08103402) to see how well it is tolerated and how it acts in the body, in healthy adults and in people with mild-to-moderate asthma. Participation may help researchers learn if this treatment could help manage asthma symptoms.
New Haven, ConnecticutAges 18–65 - NCT07655076RecruitingEarly Phase 1
Smart insulin delivery study for type 1 diabetes
This study tests a system that measures blood sugar and automatically adjusts insulin delivery. It is for adults with type 1 diabetes who use insulin injections or a pump.
Toronto, OntarioAges 18 years+ - NCT07660939RecruitingPhase 1
GPRC5D PET/CT scan for plasma cell disorders
This study uses a special PET/CT scan to look for a protein called GPRC5D in people with plasma cell disorders (like multiple myeloma). The scan might help doctors see where the disease is in the body. Healthy volunteers can also join to help compare results.
Beijing, Beijing MunicipalityAges 18–80
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.