Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT02869542Recruiting
Lymphoma registry to support future research
This trial is a lymphoma database (a way to collect and store health information). It helps researchers study people with Hodgkin or non-Hodgkin lymphoma to better understand outcomes and possibly improve future care.
Marseille, Bouches-du RhôneAges 18–95 - NCT03120481Recruiting
Check how respiratory health changes in people without lung problems
This trial enrolls adults who recently had a chest X-ray as part of routine health screening and did not show major abnormal findings, and who do not have significant breathing symptoms. It may help researchers understand changes in respiratory health over time and improve how respiratory disease risk is monitored.
Seoul, SeoulAges 19–90 - NCT01670695Recruiting
Study people with IgG4-related disease in China
This is a study that follows people diagnosed with IgG4-related disease to better understand the condition. It may help researchers confirm diagnoses and learn how the disease affects different organs over time.
Beijing, Beijing MunicipalityAges 18–75 - NCT02947945RecruitingPhase 2
Reslizumab for EGPA in adults
This trial tests reslizumab, a medicine that targets a specific immune signal, to improve symptoms in people with eosinophilic granulomatosis with polyangiitis (EGPA). It may help lower disease activity and reduce inflammation-related problems.
Denver, ColoradoAges 18 years+ - NCT03199066Recruiting
Study of non-Hodgkin lymphoma patients in the Czech Republic
This is an observational study that collects real-world information from people diagnosed with non-Hodgkin lymphoma. It does not test a new drug, but it may help doctors understand patient outcomes and care patterns.
PragueAges 18 years+ - NCT03313271Recruiting
Lymphoma patient registry for people with lymphoma
This is a registry study that collects health information from adults diagnosed with Hodgkin or non-Hodgkin lymphoma. It may help researchers learn about lymphoma care and outcomes by understanding real-world patient experiences.
Beijing, Beijing MunicipalityAges 18 years+ - NCT02149004Recruiting
HIV research study for people living with HIV
This study focuses on HIV in a research “platform” run by a university. It may help researchers learn more about HIV and improve care over time.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT03494296Recruiting
Low-dose decitabine plus COP for relapsed lymphoma
This trial studies whether a low-dose chemotherapy medicine (decitabine) combined with a COP chemotherapy regimen can help adults whose diffuse large B-cell lymphoma (DLBCL) has come back or did not respond to treatment. It may be an option if you have measurable disease and can meet key safety and health requirements.
Harbin, HeilongjiangAges 18 years+ - NCT03463564RecruitingPhase 4
Insulin pump versus insulin shots for type 1 diabetes control
This study compares an insulin pump to insulin shots to see which better improves blood sugar control and reduces swings in people with type 1 diabetes. You may be included if your diabetes is not well controlled despite education and you’ve had low blood sugar episodes.
NaplesAges 18–30 - NCT03562169RecruitingPhase 3
Ixazomib with your own stem cell transplant for relapsed myeloma
This trial studies whether adding ixazomib (an oral drug) to a transplant using your own stem cells can control relapsed multiple myeloma better. It may help by strengthening anti-myeloma treatment after the transplant, aiming to delay disease progression.
AberdeenAges 18 years+ - NCT03132311RecruitingPhase 4
Yellow fever vaccine study for certain people with HIV
This trial checks whether a yellow fever vaccine is safe and works well in adults with HIV who have relatively healthy immune function. It may help doctors understand the best way to protect people with HIV who have never had this vaccine.
Rio de JaneiroAges 18–59 - NCT03647072RecruitingPhase 3
Test drug to reduce stomach side effects during lymphoma chemotherapy
This Phase 3 trial studies whether a proton pump inhibitor (a stomach acid blocker) works better than histamine-blocking medicines when added to chemotherapy for DLBCL lymphoma. The goal is to improve how well chemotherapy is tolerated or how the treatment works.
CairoAges 18 years+ - NCT03681964Recruiting
Check tests for suspected Sjögren’s syndrome
This study follows people who have signs that might mean Sjögren’s syndrome and looks at how well a standardized work-up identifies the condition. It may help doctors confirm the diagnosis earlier and more consistently.
BrestAges 18 years+ - NCT04025450RecruitingPhase 1/Phase 2
Tested stronger combo for high-risk myeloma patients
This early-phase study compares two drug combinations—chidamide plus VRD versus VRD alone—to see which works better for primary high-risk multiple myeloma. The goal is to improve response while closely monitoring side effects and heart/lung safety.
Suzhou, JiangsuAges 18–80 - NCT03770702RecruitingPhase 3
Testing blood pressure pills and statins for rheumatoid arthritis
This trial studies whether taking a cholesterol-lowering medicine (a statin) and a blood pressure medicine (an ARB) can better control rheumatoid arthritis activity. It may help people whose rheumatoid symptoms are not fully controlled with standard care.
TantaAges 18–65 - NCT03770923RecruitingPhase 3
Testing medicines for rheumatoid arthritis activity
This trial studies whether certain medicines can improve how active rheumatoid arthritis is. If you have rheumatoid arthritis and do not have significant liver or kidney problems, you may be able to join.
TantaAges 18 years+ - NCT03818334RecruitingPhase 2/Phase 3
Cyclophosphamide after transplant for blood cancer without sibling donor
This trial studies giving cyclophosphamide after a stem cell transplant when there is no matched sibling donor, but a well-matched unrelated donor is available. It aims to improve outcomes for people with blood cancers undergoing this transplant.
São Paulo, São PauloAges 1–75 - NCT03473912Recruiting
Rheumatoid disease biobank study for adults
This study asks adults with a rheumatoid condition to join a biobank, which is a safe place to store health information and biological samples for future research. It may help researchers better understand rheumatoid conditions and develop better treatments.
Kfar SabaAges 18–120 - NCT03196414RecruitingPhase 1/Phase 2
CAR T cell therapy for relapsed myeloma with multiple targets
This trial tests an immune therapy made from T cells to attack multiple markers on multiple myeloma cells (including CD138 and BCMA). It may help people whose myeloma has come back or resisted treatment, when there are no curative options left.
Suzhou, JiangsuAges 18–75 - NCT03913962Recruiting
Exercise study for children with chronic or autoimmune conditions
This study looks at how physical activity affects muscle, metabolism (how your body uses energy), and body composition in children with certain chronic or autoimmune conditions. It may help doctors understand what types of exercise and monitoring are most beneficial and safe.
Clermont-FerrandAges 6–18 - NCT03966443Recruiting
Fluciclovine PET/CT scan for people with multiple myeloma
This trial studies how a special PET/CT scan (using fluciclovine) may help doctors evaluate multiple myeloma. You might be eligible if you’re a candidate for stem cell transplant (ASCT).
OsloAges 18 years+ - NCT03980002RecruitingPhase 2
New treatment for CLL using alternating two drug types
This trial studies an approach for people with newly diagnosed CLL/SLL (chronic lymphocytic leukemia or related disease) who need treatment. It tests whether alternating two types of chemotherapy with ibrutinib (a targeted pill) can control the disease better and safely.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT04209244Recruiting
Fish oil for cholesterol and side effects in ALL patients
This trial studies whether fish oil can improve cholesterol levels and reduce side effects in children and young adults with acute lymphoblastic leukemia (ALL) who are in lower-risk groups. If you fit the risk category, you may be asked to add fish oil as part of the study to see if it helps your lab results and well-being.
AalborgAges 1–45
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.