Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07335887RecruitingPhase 2
Sonrotoclax and dexamethasone with or without daratumumab for AL amyloidosis with t(11;14)
This trial tests a new drug combination for people with a specific type of AL amyloidosis (light chain amyloidosis) that has a genetic marker called t(11;14). The treatment includes Sonrotoclax (a targeted therapy) plus steroids, and possibly another drug called daratumumab, to see if it can help control the disease.
BeijingAges 18 years+ - NCT06060782RecruitingPhase 1
Chemo combo for high-risk blood cancer transplant patients
This trial tests a combination of drugs (thiotepa, cyclophosphamide, clarithromycin, and cytarabine) before a stem cell transplant. It is for people with certain types of blood cancer who have responded well to earlier treatment.
Zhuhai, GuangdongAges 18–65 - NCT06499480Recruiting
Italian registry of allergy shots and drops
This trial collects information from people of all ages who have allergic rhinitis, conjunctivitis, or asthma and are prescribed allergy immunotherapy (shots or drops). The goal is to understand how these treatments work in real life.
Rozzano, MilanoAges 1 year+ - NCT06862843Recruiting
Family eating habits and chronic inflammation study
This study looks at how eating habits and family health history relate to chronic inflammatory conditions like Crohn's disease, ulcerative colitis, and juvenile idiopathic arthritis. It aims to understand these links by studying families with a child or adult affected by these conditions, as well as healthy families.
Florence, ItalyAges Any age - NCT06737224Recruiting
Fasting and exercise effects on immune health
This study looks at how a 48-hour fast, alone or combined with exercise, affects your immune system and blood sugar control. It may help explain how short-term fasting can improve health in active young adults.
Kelowna, British ColumbiaAges 19–35 - NCT07328503RecruitingPhase 2
CD22 CAR T-cells to prevent relapse after CD19 CAR T-cell therapy
This trial tests if giving a second type of CAR T-cell therapy that targets CD22 can help keep B-cell acute lymphoblastic leukemia (ALL) in remission for people who are already in remission after CD19 CAR T-cell treatment. It aims to reduce the risk of the cancer coming back.
Bethesda, MarylandAges 3–65 - NCT06865274Recruiting
A look at gene changes in MS, NMOSD, and MOGAD
This study looks at a specific gene change in people with MS, NMOSD, or MOGAD to see how common it is. By joining, you help researchers learn more about these conditions and possible future treatments.
Roma, RomaAges 18 years+ - NCT07328581RecruitingPhase 2
CAR-T cell therapy for refractory lupus with or without kidney involvement
This trial tests a new treatment called ICG318 CAR-T, which uses your own immune cells to target and calm the overactive immune system in lupus. It may help people whose lupus has not improved with standard treatments, including those with lupus nephritis (kidney inflammation).
Chicago, IllinoisAges 16–70 - NCT07326995RecruitingPhase 2
Inhaled PA9159 for Adults with Moderate Asthma
This trial tests a new inhaled medicine called PA9159 for adults with moderate asthma. It compares the medicine to a placebo to see if it safely improves breathing and controls asthma symptoms.
Nanchang, JiangxiAges 18–75 - NCT07331272RecruitingPhase 1
CAR T-cells for lupus and myositis
This trial tests a new treatment using your own immune cells (CAR T-cells) targeted at a marker called CD19. It is for people whose lupus or myositis has not been controlled by other treatments.
Bengbu, AnhuiAges 18–70 - NCT07325292RecruitingPhase 3
Frexalimab injection vs IV for multiple sclerosis
This study tests if a new injection (frexalimab) works as well as the IV version for people with relapsing or certain types of secondary progressive multiple sclerosis. It could offer a more convenient way to receive this treatment at home.
Cullman, AlabamaAges 18–60 - NCT07333118RecruitingEarly Phase 1
Testing GT801 for severe autoimmune diseases
This trial tests a new treatment called GT801, a type of CAR-T cell therapy, for people with moderate to severe autoimmune diseases that have not responded to standard treatments. It aims to see if GT801 can safely and effectively control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07330934RecruitingPhase 2
Study of IBI356 for moderate to severe eczema
This study tests a new medication called IBI356 for people with moderate to severe eczema that hasn't improved with standard creams. The goal is to see if this medicine can safely reduce the redness, itching, and rash.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07330245Recruiting
Study of anifrolumab for lupus patients needing treatment
This study looks at how well anifrolumab works for people with systemic lupus erythematosus (SLE) who are starting it for the first time. It aims to see if patients can achieve a low disease activity state (LLDAS5) after treatment.
Monserrato, CAAges Any age - NCT07331467RecruitingPhase 1
Ultra-fast CAR-T cell therapy for lupus
This trial tests a new CAR-T cell treatment for people with lupus who still have moderate to severe symptoms despite trying standard medications. It aims to quickly stop the immune system from attacking the body.
Nanjing, JiangsuAges 18 years+ - NCT07332481RecruitingPhase 3
Testing enpatoran for lupus affecting the skin
This trial tests if a drug called enpatoran can help people with lupus that causes skin rashes, like discoid lupus or subacute cutaneous lupus. It may be for those with or without systemic lupus.
Los Angeles, CaliforniaAges 18–75 - NCT07330778RecruitingPhase 1
Study of CDX-622 for mild to moderate asthma
This trial is testing an investigational drug called CDX-622 for people with mild to moderate asthma. The study aims to see if it can help control asthma symptoms and improve lung function.
San Francisco, CaliforniaAges 18 years+ - NCT07326813RecruitingPhase 3
Testing D-2570 for moderate to severe plaque psoriasis
This trial tests if a new oral medication called D-2570 can safely and effectively treat moderate to severe plaque psoriasis. It may be an option if your psoriasis covers a large area and has been stable for at least 6 months.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07328035Recruiting
Asthma remission in adults with severe asthma
This study looks at whether adults with severe asthma in Thailand can reach a state where their asthma symptoms go away (remission). You may join if you have severe asthma and can do the required breathing tests.
Pathum ThaniAges 18 years+ - NCT07326930Recruiting
Nerve changes in children with leukemia during chemotherapy
This study tracks how chemotherapy affects nerves in children aged 8 to 17 with acute lymphoblastic leukemia. It aims to understand who may experience nerve problems, helping doctors better manage symptoms.
Zhengzhou, HenanAges 8–17 - NCT07328178Recruiting
Understanding IgE proteins in allergies and immune conditions
This study looks at IgE, a protein involved in allergic reactions, to better understand its role in different immune-related diseases. It aims to find out how different forms of IgE relate to health and disease, which may help improve diagnosis or treatment.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07333378Recruiting
Keeping vernix on newborns to prevent eczema
This study tests whether leaving the white, waxy coating (vernix caseosa) on a newborn’s skin after birth can help prevent the development of eczema (atopic dermatitis) in early childhood. It compares standard bathing practices with preserving this natural skin barrier.
Las Condes, RMAges birth+ - NCT07333222Recruiting
Testing a suit to help movement after stroke or MS
This study tests whether wearing a special suit (Mollii) that sends gentle electrical pulses to the body can help improve movement, balance, and daily life for people who have had a stroke or have multiple sclerosis. The suit is meant to calm overactive muscles and help you move better.
Kaposvár, Somogy CountyAges 18–99
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.