Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,502 recruiting studies in this area right now.
By phase
- Not applicable2,817
- Phase 2566
- Phase 1365
- Phase 3272
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Chronic Kidney Disease105
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Head and Neck Cancer45
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca31
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California349
- Alabama112
- Arizona104
- Florida96
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,502 total
- NCT05365672RecruitingPhase 2
Donor immune cell therapy during live kidney transplant
This Phase 2 trial studies a treatment using immune cells made from your living donor, given around the time of kidney transplant. It aims to improve transplant safety and outcomes by adjusting the immune response to the new kidney.
BerlinAges 18–69 - NCT07115446RecruitingPhase 1
Study of HS-20093 and HRS-5041 for advanced prostate cancer
This trial tests a combination of two experimental drugs, HS-20093 and HRS-5041, for men with advanced prostate cancer that has stopped responding to standard hormone therapy. The goal is to see if this new treatment can help control the cancer when other treatments have stopped working.
ShanghaiAges 18 years+ - NCT03310905Recruiting
Abdominal wall transplant for people needing multi-organ transplant
This study evaluates an abdominal wall transplant (replacing the front belly/tissue) done along with another organ transplant. It may help people who need a specialized transplant approach, but it’s only for certain candidates at Duke who meet strict safety and cancer, pregnancy, and anesthesia requirements.
Durham, North CarolinaAges 18–65 - NCT05792033Recruiting
Registry for early T1 bladder cancer after repeat bladder surgery
This study follows people with newly diagnosed early bladder cancer (T1) to better understand outcomes and guide follow-up care. You may be able to join if your cancer is confirmed after a second look bladder procedure and scans show no spread.
ViennaAges 18–90 - NCT06824987RecruitingPhase 2
Study of AZD2373 for APOL1-related kidney disease
This trial tests an experimental drug (AZD2373) for people with kidney disease caused by APOL1 gene changes. It aims to find the safest and most effective dose to slow kidney damage.
Alabaster, AlabamaAges 18–65 - NCT06323109Recruiting
MRI scan to study prostate and urinary symptoms
This study uses MRI scans to look at the prostate and bladder in people with or without lower urinary tract symptoms (like trouble peeing). The goal is to see if MRI can help doctors better understand these symptoms and guide treatment.
Madison, WisconsinAges 18–80 - NCT06336863Enrolling by invitation
DNA test to help kidney transplant patients switch to a single anti-rejection drug
This trial uses DNA testing and gene expression profiling to see if kidney transplant recipients can safely switch to a belatacept-only immunosuppression regimen. The goal is to simplify your anti-rejection drugs while keeping your kidney healthy.
Dallas, TexasAges 18 years+ - NCT07660068Enrolling by invitation
HoLEP and Sexual Recovery
This study looks at how HoLEP surgery affects sexual function, particularly ejaculation. It's for men who are getting HoLEP to relieve bothersome urinary symptoms.
Chicago, IllinoisAges 18–100 - NCT07169825RecruitingPhase 4
Pluvicto for prostate cancer with kidney or marrow issues
This trial studies how well a radioactive drug called Pluvicto works in men with prostate cancer who also have kidney or bone marrow problems. You'll get the treatment and have several scans to see how the drug affects your body.
Houston, TexasAges Any age - NCT06376968Recruiting
Testing a new dialysis option for low blood pressure
This study tests a new dialysis option called 'Biologic Fusion' that may help people who often have low blood pressure during dialysis. It compares this new method to standard dialysis to see if it is safer and works better.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06401980RecruitingPhase 2
Darolutamide for advanced prostate cancer that has stopped responding to hormone therapy
This trial tests the drug darolutamide for men whose prostate cancer has spread and is no longer controlled by standard hormone therapy. It may be an option if you've already had certain hormone treatments for at least 12 months but your cancer is still progressing.
AarauAges 18 years+ - NCT06393062Recruiting
Urine test after kidney stone surgery
This trial checks whether a simple test on the first urine after kidney stone surgery can help find infections early. It only includes adults having a specific type of stone removal who are infection-free before surgery.
AdıyamanAges 18 years+ - NCT06447740Recruiting
Stent vs. medication for narrowed kidney artery
This trial compares placing a tiny mesh tube (stent) to open the narrowed kidney artery versus continuing blood pressure medicines alone. It is for people whose high blood pressure is hard to control even with multiple medications and who have a blockage in the kidney artery that can be treated.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06324396RecruitingPhase 1
Improving drug dosing for single ventricle patients with liver disease
This trial studies how the drugs sildenafil and pravastatin work in people with a single ventricle heart condition who have had the Fontan surgery and may have related liver problems. The goal is to find the best doses based on liver function.
Kansas City, MissouriAges 8 years+ - NCT06369610RecruitingPhase 2
Less hormone therapy with radiation for prostate cancer
This trial tests whether some men with high-risk prostate cancer can safely receive less hormone therapy when combined with radiation. It aims to reduce side effects while still effectively treating the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT06879145RecruitingPhase 2/Phase 3
Study of SHR-A2102 and Adebrelimab for muscle-invasive bladder cancer
This trial tests a combination of two drugs, SHR-A2102 and Adebrelimab, for people with muscle-invasive bladder cancer that hasn't spread. The goal is to see if this treatment can help control the cancer.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06866938RecruitingPhase 2
Second course of PSMA-targeted radiation for prostate cancer
This study tests giving the targeted radiation drug [177Lu]Lu-PSMA again to men whose prostate cancer has started growing after an earlier course of the same treatment. It aims to see if a second round can control the cancer again.
BordeauxAges 18 years+ - NCT07641426RecruitingPhase 1/Phase 2
CID-103 Treatment for Kidney Transplant Rejection
This study tests an experimental drug called CID-103 to treat antibody-mediated rejection (ABMR), a type of immune response that damages transplanted kidneys. The drug targets immune cells that attack the transplant, and researchers hope it may help preserve kidney function and prevent transplant failure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06120387Recruiting
Radiation after kidney-sparing surgery for high-risk ureteral cancer
This trial tests whether adding radiation therapy after surgery that removes only part of the ureter or the entire kidney and ureter helps prevent cancer from coming back in patients who have high-risk features like aggressive cell type or deep tumor invasion.
BeijingAges 18 years+ - NCT07179705Recruiting
Predicting low blood pressure during dialysis in the ICU
This trial tests if a special tool can predict and prevent dangerous drops in blood pressure during dialysis in ICU patients with kidney problems. It might help make dialysis safer and more comfortable.
BangkokAges 18 years+ - NCT03004547Recruiting
MRI study of salt buildup in people with kidney problems
This study uses MRI scans to measure how much salt (sodium) builds up in soft tissues in people with kidney disease and related heart conditions. It may help researchers understand what’s happening in the body and how treatment or changes in care affect salt buildup.
London, OntarioAges 6 years+ - NCT06409910RecruitingPhase 2
Comparing shorter radiation treatments for prostate cancer
This study tests two slightly different short-course radiation schedules for men who have had their prostate removed and are now getting follow-up radiation. The goal is to see if one is more effective or has fewer side effects.
London, OntarioAges 18 years+ - NCT06210490RecruitingPhase 2
Antibody-drug combo with radiation for HER2+ UTUC after surgery
This trial tests a combination of an antibody-drug conjugate (Disitamab Vedotin) plus radiation therapy after surgery to prevent upper tract urothelial cancer from coming back. It is for patients with HER2-positive tumors and high-risk features who cannot receive cisplatin chemo.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06398977Recruiting
Dapagliflozin to protect kidney function in dialysis patients
This trial tests whether a diabetes drug called dapagliflozin can help people on peritoneal dialysis keep their remaining kidney function longer. It is for patients who started dialysis recently and still make urine.
Chengdu, SichuanAges 18–75
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,502 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,145 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.