Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07408531Recruiting
AI-enhanced lung cancer screening study
This trial uses artificial intelligence to better predict your lung cancer risk from your low-dose CT scan. You will watch a short video, answer a survey, and optionally give a blood sample to help improve future screening.
Chicago, IllinoisAges 50–80 - NCT06421506Recruiting
Giving surfactant through a thin tube in late preterm babies
This trial tests a less invasive way to give surfactant (a lung treatment) to babies born a few weeks early who need breathing help. It aims to see if this method works as well as standard care.
LondonAges 8 months–9 months - NCT07594067RecruitingPhase 1
TCR T cells for KRAS-mutated cancers
This trial tests a new type of immune cell therapy (TCR T cells) designed to target a specific KRAS mutation (G12V) in certain advanced cancers. It may be an option for people with pancreatic, bile duct, colorectal, or lung cancer who have already tried standard treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07286149RecruitingPhase 1/Phase 2
Study of MK-1084 plus other treatments for lung cancer
This trial tests a new drug (MK-1084) combined with other treatments for people with a specific type of advanced lung cancer (non-small cell, non-squamous) that has a KRAS G12C mutation. It is for those whose cancer has worsened after prior immunotherapy and chemotherapy.
Clermont, FloridaAges 18 years+ - NCT04870762RecruitingTeam says not enrollingPhase 2
3D-printed tongue stents during head and neck radiation
This Phase 2 study tests whether customized 3D-printed stents can be used safely during head and neck radiotherapy. If you’re having radiation (with or without chemotherapy), the stent may help make treatment easier and more precise, potentially improving the experience and outcomes.
Phoenix, ArizonaAges 18 years+ - NCT07045103Recruiting
New imaging tool for faster lung cancer detection during bronchoscopy
This trial is testing a new imaging technology that uses artificial intelligence to help doctors quickly identify lung cancer during a standard bronchoscopy procedure. If you are scheduled for a lung biopsy to check for cancer, this study may help improve detection speed and accuracy.
San Diego, CaliforniaAges 22 years+ - NCT07066813Recruiting
Lung cancer with air pockets: staging and treatment
This study looks at lung cancers that have air-filled spaces inside them. It explores how the stage of the cancer affects treatment outcomes. If you have this type of lung cancer and have had surgery, this trial may help doctors learn more about your condition.
Changsha, HunanAges Any age - NCT07037758RecruitingPhase 1
Study of tarlatamab and AB248 for extensive stage small cell lung cancer
This trial tests a new combination of two drugs, tarlatamab and AB248, for people with extensive stage small cell lung cancer that has worsened after at least one prior treatment. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Gilbert, ArizonaAges 18–90 - NCT07075068Recruiting
How smoking affects leg movement and coordination
This study tests how cigarette addiction changes the speed and coordination of your legs. If you are a smoker or a non-smoker, researchers will compare your movement to see if smoking makes a difference.
Istanbul, ÜsküdarAges 18–25 - NCT07044154Recruiting
Sun Tai Chi for heart, lung, and mental health in college students
This trial tests whether a gentle Sun-style Tai Chi program can improve your heart and lung fitness as well as your mental well-being if you have mild to moderate stress, anxiety, or depression. It's for university students who are not already very active and who are not taking mental health medicines.
Talca, Maule RegionAges 18–29 - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT07043920Recruiting
Smoking and physical activity in young adults
This study looks at how smoking affects physical activity levels in healthy young adults who are studying health sciences. It may help you understand if smoking changes your daily movement.
IstanbulAges 18–30 - NCT07019636Recruiting
Direct extubation vs. extubation after a breathing trial
This study compares two ways of removing the breathing tube (extubation) in patients who are ready to breathe on their own: taking the tube out right away, or doing a trial of breathing without the machine first. It is for people who are at low risk of needing the tube put back in.
ParisAges 18–65 - NCT06925282Recruiting
Breathing help during airway surgery
This study looks at what factors make some patients need extra breathing support during airway surgery when using a special oxygen delivery method called THRIVE. The goal is to better understand who might need additional help to keep their oxygen levels safe.
SeoulAges 18 years+ - NCT06944418Recruiting
Eosinophil function in eosinophilic lung disease
This study looks at how a type of white blood cell (eosinophil) works differently in people with eosinophilic lung diseases. It may help doctors understand these conditions better and find new treatments.
Beijing, Beijing MunicipalityAges 18–90 - NCT06992583RecruitingPhase 1
CAR-T cell therapy for advanced CEA-positive lung cancer
This trial tests a new type of immune therapy called CAR-T cells that are designed to attack lung cancer cells with a specific marker called CEA. It may be an option for people with advanced lung cancer who have already tried other treatments.
Nanjing, JiangsuAges 18 years+ - NCT06943235RecruitingPhase 2
Probiotics, radiation, chemo, and immunotherapy for limited-stage small cell lung cancer
This trial tests if adding probiotics (good bacteria) to standard chemoradiation and an immunotherapy drug (adebrelimab) can help treat limited-stage small cell lung cancer. It may improve how well the treatment works and reduce side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06969443Recruiting
Studying rehab practices in the intensive care unit
This study watches how patients in the intensive care unit are helped to move and strengthen their muscles (rehabilitation) during their stay. It does not give any new treatment or medicine, but simply documents what usual care looks like for people who need a breathing tube for more than two days.
ParisAges 18 years+ - NCT06838442Recruiting
Exercise and airway clearance education for NTM lung disease
This trial studies whether a program of exercise and airway clearance education helps people with nontuberculous mycobacterial (NTM) lung disease. It aims to improve breathing and quality of life.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06989385Recruiting
Studying breathing support failure in respiratory failure
This study looks at why some patients with acute respiratory failure do not improve with non-invasive breathing support like high-flow nasal oxygen (HFNO) or non-invasive ventilation (NIV). It aims to find patterns that might predict when these treatments are not enough.
ModenaAges 18 years+ - NCT06932276Recruiting
Smoke-free homes study for families with kids
This study tests a program to help families make their homes smoke-free, especially when there are children and smokers living together. It aims to reduce secondhand smoke exposure for kids.
Barcelona, CataloniaAges 18 years+ - NCT06975553Enrolling by invitation
Using a carbon dioxide monitor to guide safe breathing-tube removal
This study tests a special carbon dioxide monitor to help decide when it's safe to remove your breathing tube after abdominal surgery. If you are having a planned abdominal procedure lasting 1–4 hours, you may be able to join.
Beijing, Beijing MunicipalityAges 18–80 - NCT06840782RecruitingPhase 3
Immunotherapy plus local treatments for early spread lung cancer
This trial tests whether adding local treatments like radiation or surgery to standard immunotherapy can help people with lung cancer that has spread to a few spots. It aims to see if this combination improves control of the disease.
Creil, Hauts-de-FranceAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.